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ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1, ABCB1)

Short Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008].
More information related to gene ABCB1.

Products related to ABCB1 Gene:

28 results :

Human ABCB1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5738055
Datasheet
Catalog No. ABIN5738055
Type:
ORF
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Synonyms:
ABCB1, Abcb1a, abcb1.L, Abcb1b, Abcb1
Insert length:
3843 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human ABCB1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5114152
Datasheet
Catalog No. ABIN5114152
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Synonyms:
ABCB1, Abcb1a, abcb1.L, Abcb1b, Abcb1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ABCB1
Format:
Viral Particles
Storage:
-80 °C
Human ABCB1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5229492
Datasheet
Catalog No. ABIN5229492
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Synonyms:
ABCB1, Abcb1a, abcb1.L, Abcb1b, Abcb1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ABCB1
Format:
Viral Particles
Storage:
-80 °C
Human ABCB1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5114151
Datasheet
Catalog No. ABIN5114151
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Synonyms:
ABCB1, Abcb1a, abcb1.L, Abcb1b, Abcb1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of ABCB1
Format:
Viral Particles
Storage:
-80 °C
Human ABCB1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4486702
Datasheet
Catalog No. ABIN4486702
Type:
cDNA
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Synonyms:
ABCB1, Abcb1a, abcb1.L, Abcb1b, Abcb1
Insert length:
3843 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human ABCB1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4825909
Datasheet
Catalog No. ABIN4825909
Type:
cDNA
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Synonyms:
ABCB1, Abcb1a, abcb1.L, Abcb1b, Abcb1
Insert length:
3843 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human ABCB1 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4630173
Datasheet
Catalog No. ABIN4630173
Type:
cDNA
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Synonyms:
ABCB1, Abcb1a, abcb1.L, Abcb1b, Abcb1
Insert length:
3843 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human ABCB1 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4696780
Datasheet
Catalog No. ABIN4696780
Type:
cDNA
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Synonyms:
ABCB1, Abcb1a, abcb1.L, Abcb1b, Abcb1
Insert length:
3843 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human ABCB1 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4421616
Datasheet
Catalog No. ABIN4421616
Type:
cDNA
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Synonyms:
ABCB1, Abcb1a, abcb1.L, Abcb1b, Abcb1
Insert length:
3843 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human ABCB1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5229491
Datasheet
Catalog No. ABIN5229491
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1)
NCBI Accession:
NM_000927
Species:
Human
Synonyms:
ABCB1, Abcb1a, abcb1.L, Abcb1b, Abcb1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of ABCB1
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
  • Reactivity
    • Human
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • RFP tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
  • Vector Backbone
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pRFP-C-RS
    • pRS
    • pCMV6-AC-GFP
    • pCMV6-XL4
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Retroviral Vector
    • Bacterial Expression Vector
    • Cloning Vector
  • Insert
    • shRNA
    • ORF
    • cDNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to ABCB1

  • ATP binding cassette subfamily B member 1 (ABCB1)
  • ATP binding cassette subfamily B member 1A (Abcb1a)
  • ATP binding cassette subfamily B member 1 L homeolog (abcb1.L)
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b)
  • ATP binding cassette subfamily B member 1 (Abcb1)
  • ABC20
  • Abcb1
  • ABCB1
  • CD243
  • CLCS
  • GP170
  • mdr
  • MDR1
  • Mdr1
  • Mdr1a
  • Mdr1b
  • P-GP
  • p-gp
  • PGP1
  • Pgy-1
  • PGY1
  • Pgy1
  • xemdr

Gene-IDs for different species

Protein level used designations for ABCB1

  • P-glycoprotein 1
  • colchicin sensitivity
  • doxorubicin resistance
  • multidrug resistance protein 1
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1A
  • multiple drug resistant 1a
  • bovine P-glycoprotein
  • ATP-binding cassette, subfamily B, member 1
  • P-glycoprotein
  • multidrug resistance p-glycoprotein
  • multidrug resistance protein
  • ATP-binding cassette sub-family B member 1
  • P glycoprotein 1
  • multidrug resistance protein 1B
Other products related to ABCB1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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