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AIF (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1, AIFM1)

Short Description: This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, May 2010].
More information related to gene AIF.

Products related to AIF Gene:

81 results :

Mouse AIFM1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_012019
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5737803
Datasheet
Catalog No. ABIN5737803
Type:
ORF
Application:
Cloning
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_012019
Species:
Mouse
Synonyms:
AIFM1, AIF1, AIF, LOC412212, aif, aifm1, Aifm1
Insert length:
1839 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human AIFM1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5737802
Datasheet
Catalog No. ABIN5737802
Type:
ORF
Application:
Cloning
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
Species:
Human
Synonyms:
AIFM1, AIF1, AIF, LOC412212, aif, aifm1, Aifm1
Insert length:
1842 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse AIFM1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_012019
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4493035
Datasheet
Catalog No. ABIN4493035
Type:
cDNA
Application:
Protein Expression
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_012019
Species:
Mouse
Synonyms:
AIFM1, AIF1, AIF, LOC412212, aif, aifm1, Aifm1
Insert length:
1839 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat AIFM1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_031356
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5113646
Datasheet
Catalog No. ABIN5113646
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_031356
Species:
Rat
Synonyms:
AIFM1, AIF1, AIF, LOC412212, aif, aifm1, Aifm1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Aifm1
Format:
Viral Particles
Storage:
-80 °C
Mouse AIFM1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_012019
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5113644
Datasheet
Catalog No. ABIN5113644
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_012019
Species:
Mouse
Synonyms:
AIFM1, AIF1, AIF, LOC412212, aif, aifm1, Aifm1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Aifm1
Format:
Viral Particles
Storage:
-80 °C
Human AIFM1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_145813
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5113642
Datasheet
Catalog No. ABIN5113642
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_145813
Species:
Human
Synonyms:
AIFM1, AIF1, AIF, LOC412212, aif, aifm1, Aifm1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of AIFM1
Format:
Viral Particles
Storage:
-80 °C
Mouse AIFM1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_012019
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4845985
Datasheet
Catalog No. ABIN4845985
Type:
cDNA
Application:
Cloning
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_012019
Species:
Mouse
Synonyms:
AIFM1, AIF1, AIF, LOC412212, aif, aifm1, Aifm1
Insert length:
2115 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse AIFM1 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_012019
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4636504
Datasheet
Catalog No. ABIN4636504
Type:
cDNA
Application:
Cloning
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_012019
Species:
Mouse
Synonyms:
AIFM1, AIF1, AIF, LOC412212, aif, aifm1, Aifm1
Insert length:
1839 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse AIFM1 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_012019
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4716854
Datasheet
Catalog No. ABIN4716854
Type:
cDNA
Application:
Cloning
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_012019
Species:
Mouse
Synonyms:
AIFM1, AIF1, AIF, LOC412212, aif, aifm1, Aifm1
Insert length:
2115 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse AIFM1 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_012019
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4403807
Datasheet
Catalog No. ABIN4403807
Type:
cDNA
Application:
Protein Expression
Gene:
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1)
NCBI Accession:
NM_012019
Species:
Mouse
Synonyms:
AIFM1, AIF1, AIF, LOC412212, aif, aifm1, Aifm1
Insert length:
1839 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-U6-sgRNA-PGK-Neo
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pRS
    • pCas-Guide
    • pCMV6-AC
    • pCMV6-XL4
    • pCMV6-XL5
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • SFFV Promoter
    • PGK Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to AIF

  • apoptosis inducing factor mitochondria associated 1 (AIFM1)
  • allograft inflammatory factor 1 (AIF1)
  • Apoptosis inducing factor (AIF)
  • apoptosis-inducing factor 1, mitochondrial (LOC412212)
  • apoptosis inducing factor (aif)
  • apoptosis inducing factor, mitochondria associated 1 (AIFM1)
  • apoptosis inducing factor, mitochondria associated 1 (aifm1)
  • apoptosis-inducing factor, mitochondrion-associated, 1 (AIFM1)
  • apoptosis inducing factor mitochondria associated 1 (aifm1)
  • apoptosis-inducing factor, mitochondrion-associated 1 (Aifm1)
  • apoptosis inducing factor, mitochondria associated 1 (Aifm1)
  • apoptosis-inducing factor, mitochondrion-associated 1 (aifm1)
  • AIF
  • aif
  • Aif
  • AIFM1
  • AIFsh2
  • CG7263
  • CMTX4
  • COWCK
  • COXPD6
  • DDBDRAFT_0187853
  • DDBDRAFT_0191137
  • DDB_0187853
  • DDB_0191137
  • DmAIF
  • Dmel\\CG7263
  • GB16024
  • Hq
  • mAIF
  • PCD8
  • PDCD8
  • pdcd8
  • Pdcd8
  • zgc:91994

Gene-IDs for different species

Protein level used designations for AIF

  • apoptosis-inducing factor 1, mitochondrial
  • programmed cell death 8 (apoptosis-inducing factor)
  • striatal apoptosis-inducing factor
  • daintain
  • AIF-PA
  • AIF-PB
  • AIF-PC
  • CG7263-PA
  • CG7263-PB
  • CG7263-PC
  • apoptosis inducing factor
  • programmed cell death 8
  • apoptosis-inducing factor, mitochondrion-associated, 1
  • mammary apoptosis inducing factor
  • flavoprotein and apoptosis inductor
  • apoptosis-inducing factor 1, mitochondrial-like
  • harlequin
  • programmed cell death protein 8
Other products related to AIF such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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