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APP (Amyloid beta (A4) Precursor Protein, APP)

Short Description: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene APP.

Products related to APP Gene:

108 results :

Human APP ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Amyloid beta (A4) Precursor Protein (APP)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5734071
Datasheet
Catalog No. ABIN5734071
Type:
ORF
Application:
Cloning
Gene:
Amyloid beta (A4) Precursor Protein (APP)
Species:
Human
Synonyms:
APP, app, Appl, App, appa, app.L
Insert length:
918 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human APP cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA PExp Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Amyloid beta (A4) Precursor Protein (APP)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN5772493
Datasheet
Catalog No. ABIN5772493
Type:
cDNA
Application:
Protein Expression
Gene:
Amyloid beta (A4) Precursor Protein (APP)
Species:
Human
Synonyms:
APP, app, Appl, App, appa, app.L
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human APP cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA PExp Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Amyloid beta (A4) Precursor Protein (APP)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN5772494
Datasheet
Catalog No. ABIN5772494
Type:
cDNA
Application:
Protein Expression
Gene:
Amyloid beta (A4) Precursor Protein (APP)
Species:
Human
Synonyms:
APP, app, Appl, App, appa, app.L
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human APP cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Amyloid beta (A4) Precursor Protein (APP)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4472161
Datasheet
Catalog No. ABIN4472161
Type:
cDNA
Application:
Protein Expression
Gene:
Amyloid beta (A4) Precursor Protein (APP)
Species:
Human
Synonyms:
APP, app, Appl, App, appa, app.L
Insert length:
918 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat APP CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Amyloid beta (A4) Precursor Protein (APP)
NCBI Accession:
NM_019288
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5106577
Datasheet
Catalog No. ABIN5106577
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Amyloid beta (A4) Precursor Protein (APP)
NCBI Accession:
NM_019288
Species:
Rat
Synonyms:
APP, app, Appl, App, appa, app.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of App
Format:
Viral Particles
Storage:
-80 °C
Human APP CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Amyloid beta (A4) Precursor Protein (APP)
NCBI Accession:
NM_000484
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5106573
Datasheet
Catalog No. ABIN5106573
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Amyloid beta (A4) Precursor Protein (APP)
NCBI Accession:
NM_000484
Species:
Human
Synonyms:
APP, app, Appl, App, appa, app.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of APP
Format:
Viral Particles
Storage:
-80 °C
Mouse APP CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Amyloid beta (A4) Precursor Protein (APP)
NCBI Accession:
NM_001198823
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5106575
Datasheet
Catalog No. ABIN5106575
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Amyloid beta (A4) Precursor Protein (APP)
NCBI Accession:
NM_001198823
Species:
Mouse
Synonyms:
APP, app, Appl, App, appa, app.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of App
Format:
Viral Particles
Storage:
-80 °C
Human APP cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Amyloid beta (A4) Precursor Protein (APP)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4826629
Datasheet
Catalog No. ABIN4826629
Type:
cDNA
Application:
Cloning
Gene:
Amyloid beta (A4) Precursor Protein (APP)
Species:
Human
Synonyms:
APP, app, Appl, App, appa, app.L
Insert length:
918 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human APP cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Amyloid beta (A4) Precursor Protein (APP)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4758536
Datasheet
Catalog No. ABIN4758536
Type:
cDNA
Application:
Cloning
Gene:
Amyloid beta (A4) Precursor Protein (APP)
Species:
Human
Synonyms:
APP, app, Appl, App, appa, app.L
Insert length:
918 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human APP cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Amyloid beta (A4) Precursor Protein (APP)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4433256
Datasheet
Catalog No. ABIN4433256
Type:
cDNA
Application:
Protein Expression
Gene:
Amyloid beta (A4) Precursor Protein (APP)
Species:
Human
Synonyms:
APP, app, Appl, App, appa, app.L
Insert length:
918 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • DYKDDDDK Tag
    • His tag
    • His-GST
    • His-MBP
    • HA tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pPB-His-GST
    • pPB-His-MBP
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-XL5
    • pCas-Guide
    • pRFP-C-RS
    • pCMV6-XL6
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
    • SP6 Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to APP

  • amyloid beta precursor protein (APP)
  • amyloid beta (A4) precursor protein (APP)
  • amyloid beta precursor protein (app)
  • beta amyloid protein precursor-like (Appl)
  • amyloid beta precursor protein (App)
  • amyloid beta (A4) precursor protein (App)
  • amyloid beta (A4) precursor protein a (appa)
  • amyloid beta precursor protein L homeolog (app.L)
  • AAA
  • aaa
  • ABETA
  • abeta
  • Abeta
  • ABPP
  • abpp
  • Abpp
  • AD1
  • ad1
  • Adap
  • Ag
  • APP
  • app
  • APP-like
  • APPI
  • appi
  • APPL
  • appl
  • BcDNA:GH04413
  • betaApp
  • CG7727
  • CTFgamma
  • ctfgamma
  • CVAP
  • cvap
  • Cvap
  • Dmel\\CG7727
  • E030013M08Rik
  • EG:65F1.5
  • PN-II
  • PN2
  • pn2
  • wu:fj34d10
  • wu:fk65e12
  • zgc:85740

Gene-IDs for different species

Protein level used designations for APP

  • alzheimer disease amyloid protein
  • amyloid beta A4 protein
  • beta-amyloid peptide
  • cerebral vascular amyloid peptide
  • peptidase nexin-II
  • preA4
  • protease nexin-II
  • amyloid protein
  • ABPP
  • alzheimer disease amyloid A4 protein homolog
  • amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)
  • Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimers disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4)
  • amyloid beta (A4) precursor protein (peptidase nexin-2, Alzheimer disease)
  • amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease)
  • beta-amyloid precursor protein
  • Appl-PA
  • Appl-PB
  • Appl-PC
  • Appl-PD
  • Appl-PE
  • Appl-PF
  • CG7727-PA
  • CG7727-PB
  • CG7727-PC
  • CG7727-PD
  • CG7727-PE
  • CG7727-PF
  • amyloid precursor protein
  • amyloid precursor protein-like
  • beta-amyloid-protein-precursor-like
  • AG
  • amyloid A4
  • amyloidogenic glycoprotein
  • appican
  • protease nexin II
  • amyloid beta precursor protein a
  • beta-amyloid precursor protein A
Other products related to APP such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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