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ASK1 (Mitogen-Activated Protein Kinase Kinase Kinase 5, MAP3K5)

Short Description: Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells\; MAPKKK5 does not activate MAPK/ERK. [provided by RefSeq, Jul 2008].
More information related to gene ASK1.

Products related to ASK1 Gene:

41 results :

Human MAP3K5 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_005923
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5738041
Datasheet
Catalog No. ABIN5738041
Type:
ORF
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_005923
Species:
Human
Synonyms:
MAP3K5, MAPKKK5, Map3k5, map3k5
Insert length:
4125 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human MAP3K5 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_005923
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4488940
Datasheet
Catalog No. ABIN4488940
Type:
cDNA
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_005923
Species:
Human
Synonyms:
MAP3K5, MAPKKK5, Map3k5, map3k5
Insert length:
4125 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse MAP3K5 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_008580
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5114126
Datasheet
Catalog No. ABIN5114126
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_008580
Species:
Mouse
Synonyms:
MAP3K5, MAPKKK5, Map3k5, map3k5
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Map3k5
Format:
Viral Particles
Storage:
-80 °C
Human MAP3K5 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_005923
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5114124
Datasheet
Catalog No. ABIN5114124
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_005923
Species:
Human
Synonyms:
MAP3K5, MAPKKK5, Map3k5, map3k5
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of MAP3K5
Format:
Viral Particles
Storage:
-80 °C
Human MAP3K5 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_005923
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4834980
Datasheet
Catalog No. ABIN4834980
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_005923
Species:
Human
Synonyms:
MAP3K5, MAPKKK5, Map3k5, map3k5
Insert length:
4125 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human MAP3K5 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_005923
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4632409
Datasheet
Catalog No. ABIN4632409
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_005923
Species:
Human
Synonyms:
MAP3K5, MAPKKK5, Map3k5, map3k5
Insert length:
4125 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human MAP3K5 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_005923
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4705850
Datasheet
Catalog No. ABIN4705850
Type:
cDNA
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_005923
Species:
Human
Synonyms:
MAP3K5, MAPKKK5, Map3k5, map3k5
Insert length:
4125 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human MAP3K5 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_005923
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4423852
Datasheet
Catalog No. ABIN4423852
Type:
cDNA
Application:
Protein Expression
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_005923
Species:
Human
Synonyms:
MAP3K5, MAPKKK5, Map3k5, map3k5
Insert length:
4125 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse MAP3K5 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_008580
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5229466
Datasheet
Catalog No. ABIN5229466
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_008580
Species:
Mouse
Synonyms:
MAP3K5, MAPKKK5, Map3k5, map3k5
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Map3k5
Format:
Viral Particles
Storage:
-80 °C
Human MAP3K5 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_005923
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5229464
Datasheet
Catalog No. ABIN5229464
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5)
NCBI Accession:
NM_005923
Species:
Human
Synonyms:
MAP3K5, MAPKKK5, Map3k5, map3k5
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of MAP3K5
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pRS
    • pCMV6-AC-GFP
    • pCMV6-XL4
    • pCMV6-XL5
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to ASK1

  • mitogen-activated protein kinase kinase kinase 5 (MAP3K5)
  • mitogen-activated protein kinase kinase kinase 5 (MAPKKK5)
  • mitogen-activated protein kinase kinase kinase 5 (Map3k5)
  • mitogen-activated protein kinase kinase kinase 5 (map3k5)
  • 7420452D20Rik
  • ASK
  • ASK1
  • Ask1
  • MAPKKK5
  • MEKK5
  • Mekk5
  • mitogen-activated protein kinase kinase kinase 5
  • MUD21.11
  • MUD21_11
  • RGD1306565

Gene-IDs for different species

Protein level used designations for ASK1

  • ASK-1
  • MAP/ERK kinase kinase 5
  • MAPK/ERK kinase kinase 5
  • MEK kinase 5
  • MEKK 5
  • apoptosis signal regulating kinase 1
  • apoptosis signal-regulating kinase 1
  • mitogen activated protein kinase kinase kinase 5
  • mitogen-activated protein kinase kinase kinase 5
  • mitogen-activated protein kinase kinase kinase 5 pseudogene
Other products related to ASK1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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