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BIM (BCL2-Like 11 (Apoptosis Facilitator), BCL2L11)

Short Description: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jul 2008].
More information related to gene BIM.

Products related to BIM Gene:

134 results :

Human BCL2L11 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5745005
Datasheet
Catalog No. ABIN5745005
Type:
ORF
Application:
Cloning
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
Species:
Human
Synonyms:
bcl2l11, BCL2L11, Bcl2l11
Insert length:
597 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human BCL2L11 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4472600
Datasheet
Catalog No. ABIN4472600
Type:
cDNA
Application:
Protein Expression
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
Species:
Human
Synonyms:
bcl2l11, BCL2L11, Bcl2l11
Insert length:
597 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse BCL2L11 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
NCBI Accession:
NM_009754
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5242669
Datasheet
Catalog No. ABIN5242669
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
NCBI Accession:
NM_009754
Species:
Mouse
Synonyms:
bcl2l11, BCL2L11, Bcl2l11
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Bcl2l11
Format:
Viral Particles
Storage:
-80 °C
Rat BCL2L11 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
NCBI Accession:
NM_171988
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5242671
Datasheet
Catalog No. ABIN5242671
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
NCBI Accession:
NM_171988
Species:
Rat
Synonyms:
bcl2l11, BCL2L11, Bcl2l11
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Bcl2l11
Format:
Viral Particles
Storage:
-80 °C
Human BCL2L11 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
NCBI Accession:
NM_138621
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5242667
Datasheet
Catalog No. ABIN5242667
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
NCBI Accession:
NM_138621
Species:
Human
Synonyms:
bcl2l11, BCL2L11, Bcl2l11
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of BCL2L11
Format:
Viral Particles
Storage:
-80 °C
Mouse BCL2L11 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
NCBI Accession:
NM_009754
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5127244
Datasheet
Catalog No. ABIN5127244
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
NCBI Accession:
NM_009754
Species:
Mouse
Synonyms:
bcl2l11, BCL2L11, Bcl2l11
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Bcl2l11
Format:
Viral Particles
Storage:
-80 °C
Human BCL2L11 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
NCBI Accession:
NM_138621
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5127240
Datasheet
Catalog No. ABIN5127240
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
NCBI Accession:
NM_138621
Species:
Human
Synonyms:
bcl2l11, BCL2L11, Bcl2l11
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of BCL2L11
Format:
Viral Particles
Storage:
-80 °C
Human BCL2L11 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
NCBI Accession:
NM_138621
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5127241
Datasheet
Catalog No. ABIN5127241
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
NCBI Accession:
NM_138621
Species:
Human
Synonyms:
bcl2l11, BCL2L11, Bcl2l11
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of BCL2L11
Format:
Viral Particles
Storage:
-80 °C
Human BCL2L11 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
NCBI Accession:
NM_138621
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5127242
Datasheet
Catalog No. ABIN5127242
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
NCBI Accession:
NM_138621
Species:
Human
Synonyms:
bcl2l11, BCL2L11, Bcl2l11
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of BCL2L11
Format:
Viral Particles
Storage:
-80 °C
Rat BCL2L11 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
NCBI Accession:
NM_171988
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5127246
Datasheet
Catalog No. ABIN5127246
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)
NCBI Accession:
NM_171988
Species:
Rat
Synonyms:
bcl2l11, BCL2L11, Bcl2l11
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Bcl2l11
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-XL5
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pCMV6-XL4
    • pCMV6-XL6
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA
    • gRNA + Cas9
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
    • SP6 Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to BIM

  • BCL2-like 11 (bcl2l11)
  • BCL2 like 11 (BCL2L11)
  • BCL2-like 11 (apoptosis facilitator) (Bcl2l11)
  • BCL2 like 11 (Bcl2l11)
  • 1500006F24Rik
  • BAM
  • bim
  • BIM
  • Bim
  • BIMEL
  • BimL
  • BOD
  • Bod

Gene-IDs for different species

Protein level used designations for BIM

  • BCL2-like 11
  • Bcl-2 interacting mediator of cell death
  • bcl-2 interacting mediator of cell death
  • bcl-2 interacting protein Bim
  • bcl-2-like protein 11
  • bcl-2-related ovarian death agonist
  • Bcl2 interacting mediator of cell death
  • bcl2-L-11
  • bcl2-interacting mediator of cell death
  • Bcl-2 related apoptotic gene product BimL
  • bcl-2-related ovarian death protein
Other products related to BIM such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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