BRAF (B-Raf proto-oncogene, serine/threonine kinase, BRAF)
Short Description: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008].
More information related to gene BRAF.
More information related to gene BRAF.
Products related to BRAF Gene:
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44 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF)
- NCBI Accession:
- NM_004333
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF)
- NCBI Accession:
- NM_004333
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF)
- NCBI Accession:
- NM_139294
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF)
- NCBI Accession:
- NM_004333
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF)
- NCBI Accession:
- NM_139294
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF)
- NCBI Accession:
- NM_004333
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF)
- NCBI Accession:
- NM_004333
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF)
- NCBI Accession:
- NM_004333
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF)
- NCBI Accession:
- NM_004333
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-His
Kanamycin
CMV Promoter
His tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF)
- NCBI Accession:
- NM_004333
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-His
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- His tag
- Expression:
- Stable, Transient
Synonyms and alternative names related to BRAF
- B-Raf proto-oncogene, serine/threonine kinase (BRAF)
- B-Raf proto-oncogene, serine/threonine kinase (Braf)
- B-Raf proto-oncogene, serine/threonine kinase S homeolog (braf.S)
- B-Raf proto-oncogene, serine/threonine kinase (braf)
- Braf transforming gene (Braf)
- si:dkey-222f8.3 (si:dkey-222f8.3)
- 9930012E13Rik
- AA120551
- AA387315
- AA473386
- B-Raf
- B-raf
- B-RAF1
- b-raf1
- BRAF
- braf
- Braf-2
- BRAF1
- braf1
- Braf2
- C-RMIL
- C87398
- C230098H17
- D6Ertd631e
- fc48g01
- NS7
- RAFB1
- rafb1
- RMIL
- sierrabraf
- wu:fc48g01
Gene-IDs for different species
Protein level used designations for BRAF
- 94 kDa B-raf protein
- B-Raf proto-oncogene serine/threonine-protein kinase (p94)
- murine sarcoma viral (v-raf) oncogene homolog B1
- proto-oncogene B-Raf
- serine/threonine-protein kinase B-raf
- v-raf murine sarcoma viral oncogene homolog B1
- B-Raf
- B-Raf proto-oncogene serine/threonine-protein kinase
- proto-oncogene c-Rmil
- rmil serine/threonine-protein kinase
- serine/threonine kinase
- serine/threonine-protein kinase Rmil
- serine/threonine protein kinase BRAF
- serine/threonine-protein kinase B-raf-like
- B-raf protein
- uncharacterized protein LOC561722
Proteomics products related to BRAF Gene
Other products related to BRAF such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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