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BRCC3 (BRCA1/BRCA2-Containing Complex, Subunit 3, BRCC3)

Short Description: This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response, where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains, and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya, a cerebrovascular angiopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jun 2011].
More information related to gene BRCC3.

Products related to BRCC3 Gene:

73 results :

Human BRCC3 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5738359
Datasheet
Catalog No. ABIN5738359
Type:
ORF
Application:
Cloning
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
Species:
Human
Synonyms:
BRCC3, depdc1b, brcc3, Brcc3, brcc3.L
Insert length:
951 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human BRCC3 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4472678
Datasheet
Catalog No. ABIN4472678
Type:
cDNA
Application:
Protein Expression
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
Species:
Human
Synonyms:
BRCC3, depdc1b, brcc3, Brcc3, brcc3.L
Insert length:
951 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat BRCC3 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
NCBI Accession:
NM_001127300
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5114774
Datasheet
Catalog No. ABIN5114774
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
NCBI Accession:
NM_001127300
Species:
Rat
Synonyms:
BRCC3, depdc1b, brcc3, Brcc3, brcc3.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Brcc3
Format:
Viral Particles
Storage:
-80 °C
Mouse BRCC3 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
NCBI Accession:
NM_001166457
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5114772
Datasheet
Catalog No. ABIN5114772
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
NCBI Accession:
NM_001166457
Species:
Mouse
Synonyms:
BRCC3, depdc1b, brcc3, Brcc3, brcc3.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Brcc3
Format:
Viral Particles
Storage:
-80 °C
Human BRCC3 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
NCBI Accession:
NM_024332
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5114770
Datasheet
Catalog No. ABIN5114770
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
NCBI Accession:
NM_024332
Species:
Human
Synonyms:
BRCC3, depdc1b, brcc3, Brcc3, brcc3.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of BRCC3
Format:
Viral Particles
Storage:
-80 °C
Human BRCC3 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4759053
Datasheet
Catalog No. ABIN4759053
Type:
cDNA
Application:
Cloning
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
Species:
Human
Synonyms:
BRCC3, depdc1b, brcc3, Brcc3, brcc3.L
Insert length:
951 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human BRCC3 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4827329
Datasheet
Catalog No. ABIN4827329
Type:
cDNA
Application:
Cloning
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
Species:
Human
Synonyms:
BRCC3, depdc1b, brcc3, Brcc3, brcc3.L
Insert length:
951 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human BRCC3 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4698200
Datasheet
Catalog No. ABIN4698200
Type:
cDNA
Application:
Cloning
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
Species:
Human
Synonyms:
BRCC3, depdc1b, brcc3, Brcc3, brcc3.L
Insert length:
951 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human BRCC3 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4433773
Datasheet
Catalog No. ABIN4433773
Type:
cDNA
Application:
Protein Expression
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
Species:
Human
Synonyms:
BRCC3, depdc1b, brcc3, Brcc3, brcc3.L
Insert length:
951 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse BRCC3 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
NCBI Accession:
NM_001166457
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5738360
Datasheet
Catalog No. ABIN5738360
Type:
ORF
Application:
Cloning
Gene:
BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3)
NCBI Accession:
NM_001166457
Species:
Mouse
Synonyms:
BRCC3, depdc1b, brcc3, Brcc3, brcc3.L
Insert length:
876 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to BRCC3

  • BRCA1/BRCA2-containing complex subunit 3 (BRCC3)
  • DEP domain containing 1B (depdc1b)
  • BRCA1/BRCA2-containing complex subunit 3 (brcc3)
  • BRCA1/BRCA2-containing complex, subunit 3 (Brcc3)
  • BRCA1/BRCA2-containing complex subunit 3 L homeolog (brcc3.L)
  • BRCC3
  • brcc3
  • BRCC36
  • brcc36
  • C6.1A
  • CXorf53
  • xtp1

Gene-IDs for different species

Protein level used designations for BRCC3

  • BRCA1/BRCA2-containing complex, subunit 3
  • c6.1A
  • BRCA1-A complex subunit BRCC36
  • BRCA1/BRCA2-containing complex subunit 3
  • BRCA1/BRCA2-containing complex subunit 36
  • BRISC complex subunit BRCC36
  • lys-63-specific deubiquitinase BRCC36
  • 6.1A protein
Other products related to BRCC3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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