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CACNA1A (Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit, CACNA1A)

Short Description: Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas, the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1A subunit, which is predominantly expressed in neuronal tissue. Mutations in this gene are associated with 2 neurologic disorders, familial hemiplegic migraine and episodic ataxia 2. This gene also exhibits polymorphic variation due to (CAG)n-repeats. Multiple transcript variants encoding different isoforms have been found for this gene. In one set of transcript variants, the (CAG)n-repeats occur in the 3' UTR, and are not associated with any disease. But in another set of variants, an insertion extends the coding region to include the (CAG)n-repeats which encode a polyglutamine tract. Expansion of the (CAG)n-repeats from the normal 4-16 to 21-28 in the coding region is associated with spinocerebellar ataxia 6. [provided by RefSeq, Mar 2010].
More information related to gene CACNA1A.

Products related to CACNA1A Gene:

68 results :

Mouse CACNA1A CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_007578
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5115024
Datasheet
Catalog No. ABIN5115024
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_007578
Species:
Mouse
Synonyms:
cacna1a.S, cacna1aa, CACNA1A, Cacna1a, LOC395892
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cacna1a
Format:
Viral Particles
Storage:
-80 °C
Human CACNA1A CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_000068
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5115022
Datasheet
Catalog No. ABIN5115022
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_000068
Species:
Human
Synonyms:
cacna1a.S, cacna1aa, CACNA1A, Cacna1a, LOC395892
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of CACNA1A
Format:
Viral Particles
Storage:
-80 °C
Rat CACNA1A CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_012918
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5115026
Datasheet
Catalog No. ABIN5115026
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_012918
Species:
Rat
Synonyms:
cacna1a.S, cacna1aa, CACNA1A, Cacna1a, LOC395892
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cacna1a
Format:
Viral Particles
Storage:
-80 °C
Rat CACNA1A CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_012918
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5230372
Datasheet
Catalog No. ABIN5230372
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_012918
Species:
Rat
Synonyms:
cacna1a.S, cacna1aa, CACNA1A, Cacna1a, LOC395892
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cacna1a
Format:
Viral Particles
Storage:
-80 °C
Mouse CACNA1A CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_007578
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5230370
Datasheet
Catalog No. ABIN5230370
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_007578
Species:
Mouse
Synonyms:
cacna1a.S, cacna1aa, CACNA1A, Cacna1a, LOC395892
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cacna1a
Format:
Viral Particles
Storage:
-80 °C
Human CACNA1A CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_000068
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5230368
Datasheet
Catalog No. ABIN5230368
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_000068
Species:
Human
Synonyms:
cacna1a.S, cacna1aa, CACNA1A, Cacna1a, LOC395892
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of CACNA1A
Format:
Viral Particles
Storage:
-80 °C
Rat CACNA1A CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_012918
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5115025
Datasheet
Catalog No. ABIN5115025
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_012918
Species:
Rat
Synonyms:
cacna1a.S, cacna1aa, CACNA1A, Cacna1a, LOC395892
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Cacna1a
Format:
Viral Particles
Storage:
-80 °C
Mouse CACNA1A CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_007578
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5115023
Datasheet
Catalog No. ABIN5115023
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_007578
Species:
Mouse
Synonyms:
cacna1a.S, cacna1aa, CACNA1A, Cacna1a, LOC395892
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Cacna1a
Format:
Viral Particles
Storage:
-80 °C
Human CACNA1A CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_000068
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5115021
Datasheet
Catalog No. ABIN5115021
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_000068
Species:
Human
Synonyms:
cacna1a.S, cacna1aa, CACNA1A, Cacna1a, LOC395892
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of CACNA1A
Format:
Viral Particles
Storage:
-80 °C
Rat CACNA1A CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_012918
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5230371
Datasheet
Catalog No. ABIN5230371
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A)
NCBI Accession:
NM_012918
Species:
Rat
Synonyms:
cacna1a.S, cacna1aa, CACNA1A, Cacna1a, LOC395892
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Cacna1a
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
  • Reactivity
    • Mouse
    • Human
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • Myc-DYKDDDDK Tag
    • GFP tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pLenti-C-Myc-DDK
    • pORF
    • pCMV6-XL5
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to CACNA1A

  • calcium channel, voltage-dependent, P/Q type, alpha 1A subunit S homeolog (cacna1a.S)
  • calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a (cacna1aa)
  • calcium voltage-gated channel subunit alpha1 A (CACNA1A)
  • calcium voltage-gated channel subunit alpha1 A (Cacna1a)
  • calcium channel, voltage-dependent, P/Q type, alpha 1A subunit (Cacna1a)
  • P/Q-type voltage-gated calcium channel alpha1A subunit ChCaChA1A (LOC395892)
  • alpha1A
  • APCA
  • BccA1
  • BI
  • ca(v)2.1
  • Caca1a
  • CACH4
  • CACN3
  • cacna-a
  • cacna1a
  • CACNL1A4
  • Cacnl1a4
  • cav2.1
  • Cav2.1
  • CAV2.1
  • Ccha1a
  • EA2
  • FHM
  • HPCA
  • la
  • leaner
  • MHP
  • MHP1
  • nmf352
  • rbA-1
  • rkr
  • rocker
  • SCA6
  • si:ch211-237k17.1
  • tg
  • tottering

Gene-IDs for different species

Protein level used designations for CACNA1A

  • calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
  • voltage-dependent calcium ion channel alpha subunit
  • ZfCav2.1
  • BI
  • RBA-I
  • brain calcium channel 1
  • brain calcium channel I
  • brain class A
  • calcium channel alpha 1A
  • calcium channel, L type, alpha-1 polypeptide
  • calcium channel, voltage-dependent, alpha 1A subunit
  • voltage-dependent P/Q-type calcium channel subunit alpha-1A
  • voltage-gated calcium channel subunit alpha Cav2.1
  • P/Q-type calcium channel alpha1A subunit
  • calcium channel, P/Q type, alpha 1A
  • calcium channel, alpha 1A subunit
  • voltage-gated calcium channel alpha 1A subunit
  • calcium channel BI-1
  • calcium channel BI-2
Other products related to CACNA1A such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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