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CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2, CBFA2T2)

Short Description: In acute myeloid leukemia, especially in the M2 subtype, the t(8\;21)(q22\;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described. [provided by RefSeq, Jul 2008].
More information related to gene CBFA2T2.

Products related to CBFA2T2 Gene:

69 results :

Human CBFA2T2 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5733220
Datasheet
Catalog No. ABIN5733220
Type:
ORF
Application:
Cloning
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
Species:
Human
Synonyms:
Cbfa2t2, CBFA2T2, cbfa2t2.L
Insert length:
1845 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human CBFA2T2 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5733221
Datasheet
Catalog No. ABIN5733221
Type:
ORF
Application:
Cloning
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
Species:
Human
Synonyms:
Cbfa2t2, CBFA2T2, cbfa2t2.L
Insert length:
792 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human CBFA2T2 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4473521
Datasheet
Catalog No. ABIN4473521
Type:
cDNA
Application:
Protein Expression
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
Species:
Human
Synonyms:
Cbfa2t2, CBFA2T2, cbfa2t2.L
Insert length:
1845 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human CBFA2T2 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4473520
Datasheet
Catalog No. ABIN4473520
Type:
cDNA
Application:
Protein Expression
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
Species:
Human
Synonyms:
Cbfa2t2, CBFA2T2, cbfa2t2.L
Insert length:
1845 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat CBFA2T2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
NCBI Accession:
NM_001168542
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5105091
Datasheet
Catalog No. ABIN5105091
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
NCBI Accession:
NM_001168542
Species:
Rat
Synonyms:
Cbfa2t2, CBFA2T2, cbfa2t2.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cbfa2t2
Format:
Viral Particles
Storage:
-80 °C
Mouse CBFA2T2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
NCBI Accession:
NM_172860
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5105089
Datasheet
Catalog No. ABIN5105089
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
NCBI Accession:
NM_172860
Species:
Mouse
Synonyms:
Cbfa2t2, CBFA2T2, cbfa2t2.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cbfa2t2
Format:
Viral Particles
Storage:
-80 °C
Human CBFA2T2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
NCBI Accession:
NM_005093
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5105087
Datasheet
Catalog No. ABIN5105087
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
NCBI Accession:
NM_005093
Species:
Human
Synonyms:
Cbfa2t2, CBFA2T2, cbfa2t2.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of CBFA2T2
Format:
Viral Particles
Storage:
-80 °C
Human CBFA2T2 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4759896
Datasheet
Catalog No. ABIN4759896
Type:
cDNA
Application:
Cloning
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
Species:
Human
Synonyms:
Cbfa2t2, CBFA2T2, cbfa2t2.L
Insert length:
1845 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human CBFA2T2 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4759895
Datasheet
Catalog No. ABIN4759895
Type:
cDNA
Application:
Cloning
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
Species:
Human
Synonyms:
Cbfa2t2, CBFA2T2, cbfa2t2.L
Insert length:
1845 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human CBFA2T2 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4828324
Datasheet
Catalog No. ABIN4828324
Type:
cDNA
Application:
Cloning
Gene:
Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2)
Species:
Human
Synonyms:
Cbfa2t2, CBFA2T2, cbfa2t2.L
Insert length:
1845 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • His tag
    • GFP tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pDONR223
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-XL5
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Lentiviral Vector
    • Cloning Vector
    • Retroviral Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Spectinomycin
    • Chloramphenicol
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Liquid
    • Lyophilized
    • Viral Particles

Synonyms and alternative names related to CBFA2T2

  • CBFA2/RUNX1 translocation partner 2 (Cbfa2t2)
  • CBFA2/RUNX1 translocation partner 2 (CBFA2T2)
  • core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human) (Cbfa2t2)
  • CBFA2/RUNX1 translocation partner 2 L homeolog (cbfa2t2.L)
  • A430091M07
  • C330013D05Rik
  • cbfa2t2-a
  • Cbfa2t2h
  • EHT
  • MTGR1
  • p85
  • XETOR
  • ZMYND3

Gene-IDs for different species

Protein level used designations for CBFA2T2

  • translocated to, 2
  • myeloid translocation gene-related protein 1
  • protein CBFA2T2
  • CBFA2T2 identified gene homolog
  • MTG8-like protein
  • MTG8-related protein 1
  • core-binding factor runt domain alpha subunit 2 translocated to 2 homolog
  • core-binding factor, runt domain, alpha subunit 2, translocated to, 2 homolog
  • ETO homolog on chromosome 20
  • ETO homologous on chromosome 20
  • myeloid translocation-related protein 1
  • a subunit 2; translocated to, 2
  • expressed during neurogenesis
Other products related to CBFA2T2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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