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CD46 (CD46, CD46)

Short Description: The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010].
More information related to gene CD46.

Products related to CD46 Gene:

112 results :

Human CD46 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5755151
Datasheet
Catalog No. ABIN5755151
Type:
ORF
Application:
Cloning
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
Species:
Human
Synonyms:
CD46, Cd46, LOC100341359, LOC103789310
Insert length:
1155 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human CD46 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4473742
Datasheet
Catalog No. ABIN4473742
Type:
cDNA
Application:
Protein Expression
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
Species:
Human
Synonyms:
CD46, Cd46, LOC100341359, LOC103789310
Insert length:
1155 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat CD46 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
NCBI Accession:
NM_019190
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5262921
Datasheet
Catalog No. ABIN5262921
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
NCBI Accession:
NM_019190
Species:
Rat
Synonyms:
CD46, Cd46, LOC100341359, LOC103789310
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cd46
Format:
Viral Particles
Storage:
-80 °C
Mouse CD46 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
NCBI Accession:
NM_010778
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5262919
Datasheet
Catalog No. ABIN5262919
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
NCBI Accession:
NM_010778
Species:
Mouse
Synonyms:
CD46, Cd46, LOC100341359, LOC103789310
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cd46
Format:
Viral Particles
Storage:
-80 °C
Human CD46 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
NCBI Accession:
NM_172353
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5262917
Datasheet
Catalog No. ABIN5262917
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
NCBI Accession:
NM_172353
Species:
Human
Synonyms:
CD46, Cd46, LOC100341359, LOC103789310
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of CD46
Format:
Viral Particles
Storage:
-80 °C
Rat CD46 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
NCBI Accession:
NM_019190
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5147398
Datasheet
Catalog No. ABIN5147398
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
NCBI Accession:
NM_019190
Species:
Rat
Synonyms:
CD46, Cd46, LOC100341359, LOC103789310
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cd46
Format:
Viral Particles
Storage:
-80 °C
Human CD46 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
NCBI Accession:
NM_172353
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5147394
Datasheet
Catalog No. ABIN5147394
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
NCBI Accession:
NM_172353
Species:
Human
Synonyms:
CD46, Cd46, LOC100341359, LOC103789310
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of CD46
Format:
Viral Particles
Storage:
-80 °C
Mouse CD46 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
NCBI Accession:
NM_010778
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5147396
Datasheet
Catalog No. ABIN5147396
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
NCBI Accession:
NM_010778
Species:
Mouse
Synonyms:
CD46, Cd46, LOC100341359, LOC103789310
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cd46
Format:
Viral Particles
Storage:
-80 °C
Human CD46 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4760117
Datasheet
Catalog No. ABIN4760117
Type:
cDNA
Application:
Cloning
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
Species:
Human
Synonyms:
CD46, Cd46, LOC100341359, LOC103789310
Insert length:
1155 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human CD46 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4828658
Datasheet
Catalog No. ABIN4828658
Type:
cDNA
Application:
Cloning
Gene:
CD46 Molecule, Complement Regulatory Protein (CD46)
Species:
Human
Synonyms:
CD46, Cd46, LOC100341359, LOC103789310
Insert length:
1155 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pcDNA3.1+C-(K)-DYK
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-XL4
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pRFP-C-RS
    • pCMV6-XL5
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • Enhanced CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Viral Particles
    • Liquid

Synonyms and alternative names related to CD46

  • CD46 molecule (CD46)
  • CD46 antigen, complement regulatory protein (Cd46)
  • CD46 molecule (Cd46)
  • CD46 molecule, complement regulatory protein (CD46)
  • membrane cofactor protein-like (LOC100341359)
  • membrane cofactor protein-like (LOC103789310)
  • AHUS2
  • CD46
  • MCP
  • Mcp
  • MIC10
  • TLX
  • TRA2.10

Gene-IDs for different species

Protein level used designations for CD46

  • CD46 antigen, complement regulatory protein
  • antigen identified by monoclonal antibody TRA-2-10
  • complement membrane cofactor protein
  • measles virus receptor
  • membrane cofactor protein
  • membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen)
  • trophoblast leucocyte common antigen
  • trophoblast leukocyte common antigen
  • trophoblast-lymphocyte cross-reactive antigen
  • brain microvascular membrane cofactor
  • membrane cofactor protein(GMP1-full)
  • CD46 molecule
  • Membrane cofactor protein
Other products related to CD46 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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