CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4), CDKN2B)
Short Description: This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008].
More information related to gene CDKN2B.
More information related to gene CDKN2B.
Products related to CDKN2B Gene:
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32 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B)
- NCBI Accession:
- NM_130812
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B)
- NCBI Accession:
- NM_007670
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B)
- NCBI Accession:
- NM_004936
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B)
- NCBI Accession:
- NM_007670
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B)
- NCBI Accession:
- NM_004936
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B)
- NCBI Accession:
- NM_130812
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
Synonyms and alternative names related to CDKN2B
- cyclin dependent kinase inhibitor 2B (CDKN2B)
- Cyclin-dependent kinase 4 inhibitor B (cdn2b)
- cyclin-dependent kinase inhibitor 2B (cdkn2b)
- cyclin-dependent kinase inhibitor 2B L homeolog (cdkn2b.L)
- cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) (Cdkn2b)
- cyclin-dependent kinase inhibitor 2B (Cdkn2b)
- AV083695
- CDK4I
- cdk4l
- CDKN2A
- ink4b
- INK4B
- INK4b
- mts2
- MTS2
- p14-INK4b
- p15
- P15
- p15(INK4b)
- p15ink4b
- p15INK4b
- tp15
- TP15
Gene-IDs for different species
Protein level used designations for CDKN2B
- Cyclin-dependent kinase 4 inhibitor B
- CDK inhibitory protein
- CDK4B inhibitor
- MTS-2
- cyclin-dependent kinase 4 inhibitor B
- cyclin-dependent kinases 4 and 6 binding protein
- multiple tumor suppressor 2
- p14-INK4b
- p14_CDK inhibitor
- p14_INK4B
- p15 CDK inhibitor
- p15-INK4b
- p15_INK4B
- cyclin-dependent kinase inhibitor p15
- cyclin-dependent kinase inhibitor p15INK4b
- cyclin-dependent kinase inhibitor protein
- Cyclin dependent kinase inhibitor 2B (p15, inhibits CDK4)
- cyclin dependant kinase inhibitor
- cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
- cyclin-dependent kinase inhibitor 2B
- cyclin-dependent kinase inhibitor 2B (melanoma, p16, inhibits CDK4)
- p15INK4b tumor suppressor
Proteomics products related to CDKN2B Gene
Other products related to CDKN2B such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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