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CHEK1 (Checkpoint Kinase 1, CHEK1)

Short Description: The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011].
More information related to gene CHEK1.

Products related to CHEK1 Gene:

67 results :

Human CHEK1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_001274
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5755167
Datasheet
Catalog No. ABIN5755167
Type:
ORF
Application:
Cloning
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_001274
Species:
Human
Synonyms:
CHEK1, ANI_1_2436074, AOR_1_768154, PTRG_04183, SJAG_01680, PAAG_04978, MCYG_03290, VDBG_03742, chek1.S, Chek1, chek1
Insert length:
1431 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human CHEK1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_001274
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4487442
Datasheet
Catalog No. ABIN4487442
Type:
cDNA
Application:
Protein Expression
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_001274
Species:
Human
Synonyms:
CHEK1, ANI_1_2436074, AOR_1_768154, PTRG_04183, SJAG_01680, PAAG_04978, MCYG_03290, VDBG_03742, chek1.S, Chek1, chek1
Insert length:
1431 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat CHEK1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_080400
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5262949
Datasheet
Catalog No. ABIN5262949
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_080400
Species:
Rat
Synonyms:
CHEK1, ANI_1_2436074, AOR_1_768154, PTRG_04183, SJAG_01680, PAAG_04978, MCYG_03290, VDBG_03742, chek1.S, Chek1, chek1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Chek1
Format:
Viral Particles
Storage:
-80 °C
Mouse CHEK1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_007691
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5262947
Datasheet
Catalog No. ABIN5262947
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_007691
Species:
Mouse
Synonyms:
CHEK1, ANI_1_2436074, AOR_1_768154, PTRG_04183, SJAG_01680, PAAG_04978, MCYG_03290, VDBG_03742, chek1.S, Chek1, chek1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Chek1
Format:
Viral Particles
Storage:
-80 °C
Human CHEK1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_001114121
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5262945
Datasheet
Catalog No. ABIN5262945
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_001114121
Species:
Human
Synonyms:
CHEK1, ANI_1_2436074, AOR_1_768154, PTRG_04183, SJAG_01680, PAAG_04978, MCYG_03290, VDBG_03742, chek1.S, Chek1, chek1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of CHEK1
Format:
Viral Particles
Storage:
-80 °C
Rat CHEK1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_080400
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5147426
Datasheet
Catalog No. ABIN5147426
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_080400
Species:
Rat
Synonyms:
CHEK1, ANI_1_2436074, AOR_1_768154, PTRG_04183, SJAG_01680, PAAG_04978, MCYG_03290, VDBG_03742, chek1.S, Chek1, chek1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Chek1
Format:
Viral Particles
Storage:
-80 °C
Mouse CHEK1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_007691
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5147424
Datasheet
Catalog No. ABIN5147424
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_007691
Species:
Mouse
Synonyms:
CHEK1, ANI_1_2436074, AOR_1_768154, PTRG_04183, SJAG_01680, PAAG_04978, MCYG_03290, VDBG_03742, chek1.S, Chek1, chek1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Chek1
Format:
Viral Particles
Storage:
-80 °C
Human CHEK1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_001114121
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5147422
Datasheet
Catalog No. ABIN5147422
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_001114121
Species:
Human
Synonyms:
CHEK1, ANI_1_2436074, AOR_1_768154, PTRG_04183, SJAG_01680, PAAG_04978, MCYG_03290, VDBG_03742, chek1.S, Chek1, chek1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of CHEK1
Format:
Viral Particles
Storage:
-80 °C
Human CHEK1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_001274
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4828965
Datasheet
Catalog No. ABIN4828965
Type:
cDNA
Application:
Cloning
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_001274
Species:
Human
Synonyms:
CHEK1, ANI_1_2436074, AOR_1_768154, PTRG_04183, SJAG_01680, PAAG_04978, MCYG_03290, VDBG_03742, chek1.S, Chek1, chek1
Insert length:
1431 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human CHEK1 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_001274
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4630912
Datasheet
Catalog No. ABIN4630912
Type:
cDNA
Application:
Cloning
Gene:
Checkpoint Kinase 1 (CHEK1)
NCBI Accession:
NM_001274
Species:
Human
Synonyms:
CHEK1, ANI_1_2436074, AOR_1_768154, PTRG_04183, SJAG_01680, PAAG_04978, MCYG_03290, VDBG_03742, chek1.S, Chek1, chek1
Insert length:
1431 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL4
    • pCMV6-XL5
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to CHEK1

  • checkpoint kinase 1 (CHEK1)
  • serine/threonine-protein kinase chk1 (ANI_1_2436074)
  • serine/threonine-protein kinase chk1 (AOR_1_768154)
  • serine/threonine-protein kinase Chk1 (PTRG_04183)
  • CAMK/CAMKL/CHK1 protein kinase Chk1 (SJAG_01680)
  • serine/threonine-protein kinase chk1 (PAAG_04978)
  • serine/threonine-protein kinase chk1 (MCYG_03290)
  • serine/threonine-protein kinase chk1 (VDBG_03742)
  • checkpoint kinase 1 S homeolog (chek1.S)
  • checkpoint kinase 1 (Chek1)
  • checkpoint kinase 1 (chek1)
  • An08g10320
  • AO090003000441
  • C85740
  • CHEK1
  • CHK1
  • chk1
  • Chk1
  • id:ibd2720
  • rad27
  • zgc:56093

Gene-IDs for different species

Protein level used designations for CHEK1

  • CHK1 checkpoint homolog
  • Serine/threonine-protein kinase Chk1-like protein
  • serine/threonine-protein kinase Chk1
  • serine/threonine-protein kinase chk1
  • Checkpoint, S. pombe, homolog of, 1
  • Chk1-S
  • cell cycle checkpoint kinase
  • checkpoint kinase-1
  • Chk1 checkpoint kinase
  • xChk1
  • checkpoint kinase 1 homolog
  • rad27 homolog
  • 2720
  • integral membrane protein 1
Other products related to CHEK1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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