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CLCN1 (Chloride Channel 1, Skeletal Muscle, CLCN1)

Short Description: The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012].
More information related to gene CLCN1.

Products related to CLCN1 Gene:

59 results :

Human CLCN1 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA PExp Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN5772798
Datasheet
Catalog No. ABIN5772798
Type:
cDNA
Application:
Protein Expression
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
Species:
Human
Synonyms:
CLCN1, clcn1a, LOC100550479, LOC703944, Clcn1
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human CLCN1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA PExp Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN5772797
Datasheet
Catalog No. ABIN5772797
Type:
cDNA
Application:
Protein Expression
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
Species:
Human
Synonyms:
CLCN1, clcn1a, LOC100550479, LOC703944, Clcn1
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human CLCN1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5744272
Datasheet
Catalog No. ABIN5744272
Type:
ORF
Application:
Cloning
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
Species:
Human
Synonyms:
CLCN1, clcn1a, LOC100550479, LOC703944, Clcn1
Insert length:
2967 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse CLCN1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
NCBI Accession:
NM_013491
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5241305
Datasheet
Catalog No. ABIN5241305
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
NCBI Accession:
NM_013491
Species:
Mouse
Synonyms:
CLCN1, clcn1a, LOC100550479, LOC703944, Clcn1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Clcn1
Format:
Viral Particles
Storage:
-80 °C
Human CLCN1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
NCBI Accession:
NM_000083
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5241303
Datasheet
Catalog No. ABIN5241303
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
NCBI Accession:
NM_000083
Species:
Human
Synonyms:
CLCN1, clcn1a, LOC100550479, LOC703944, Clcn1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of CLCN1
Format:
Viral Particles
Storage:
-80 °C
Rat CLCN1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
NCBI Accession:
NM_013147
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5241307
Datasheet
Catalog No. ABIN5241307
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
NCBI Accession:
NM_013147
Species:
Rat
Synonyms:
CLCN1, clcn1a, LOC100550479, LOC703944, Clcn1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Clcn1
Format:
Viral Particles
Storage:
-80 °C
Rat CLCN1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
NCBI Accession:
NM_013147
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5125896
Datasheet
Catalog No. ABIN5125896
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
NCBI Accession:
NM_013147
Species:
Rat
Synonyms:
CLCN1, clcn1a, LOC100550479, LOC703944, Clcn1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Clcn1
Format:
Viral Particles
Storage:
-80 °C
Mouse CLCN1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
NCBI Accession:
NM_013491
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5125894
Datasheet
Catalog No. ABIN5125894
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
NCBI Accession:
NM_013491
Species:
Mouse
Synonyms:
CLCN1, clcn1a, LOC100550479, LOC703944, Clcn1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Clcn1
Format:
Viral Particles
Storage:
-80 °C
Human CLCN1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
NCBI Accession:
NM_000083
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5125892
Datasheet
Catalog No. ABIN5125892
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
NCBI Accession:
NM_000083
Species:
Human
Synonyms:
CLCN1, clcn1a, LOC100550479, LOC703944, Clcn1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of CLCN1
Format:
Viral Particles
Storage:
-80 °C
Rat CLCN1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
NCBI Accession:
NM_013147
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5744274
Datasheet
Catalog No. ABIN5744274
Type:
ORF
Application:
Cloning
Gene:
Chloride Channel 1, Skeletal Muscle (CLCN1)
NCBI Accession:
NM_013147
Species:
Rat
Synonyms:
CLCN1, clcn1a, LOC100550479, LOC703944, Clcn1
Insert length:
2985 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • His-GST
    • His-MBP
    • HA tag
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pPB-His-GST
    • pPB-His-MBP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to CLCN1

  • chloride voltage-gated channel 1 (CLCN1)
  • chloride channel, voltage-sensitive 1a (clcn1a)
  • chloride channel protein 1 (LOC100550479)
  • chloride channel protein 1 (LOC703944)
  • chloride channel, voltage-sensitive 1 (Clcn1)
  • chloride voltage-gated channel 1 (Clcn1)
  • adr
  • Clc-1
  • Clc1
  • CLC1
  • CLCN1
  • mto
  • myotonia
  • nmf355
  • si:dkey-14o18.5
  • SMCC
  • SMCC1

Gene-IDs for different species

Protein level used designations for CLCN1

  • chloride channel 1, skeletal muscle
  • chloride channel 1, skeletal muscle (Thomsen disease, autosomal dominant)
  • chloride channel protein 1-like
  • similar to chloride channel 1, skeletal muscle (Thomsen disease, autosomal dominant)
  • arrested development of righting response
  • chloride channel protein 1
  • chloride channel protein, skeletal muscle
  • chloride channel 1, skeletal muscle C-type
  • clC-1
  • skeletal muscle chloride channel 1
  • skeletal muscle chloride channel ClC-1
Other products related to CLCN1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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