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CLCN3 (Chloride Channel 3, CLCN3)

Short Description: This gene encodes a member of the voltage-gated chloride channel (ClC) family. The encoded protein is present in all cell types and localized in plasma membranes and in intracellular vesicles. It is a multi-pass membrane protein which contains a ClC domain and two additional C-terminal CBS (cystathionine beta-synthase) domains. The ClC domain catalyzes the selective flow of Cl- ions across cell membranes, and the CBS domain may have a regulatory function. This protein plays a role in both acidification and transmitter loading of GABAergic synaptic vesicles, and in smooth muscle cell activation and neointima formation. This protein is required for lysophosphatidic acid (LPA)-activated Cl- current activity and fibroblast-to-myofibroblast differentiation. The protein activity is regulated by Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) in glioma cells. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].
More information related to gene CLCN3.

Products related to CLCN3 Gene:

69 results :

Human CLCN3 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Chloride Channel 3 (CLCN3)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4829105
Datasheet
Catalog No. ABIN4829105
Type:
cDNA
Application:
Cloning
Gene:
Chloride Channel 3 (CLCN3)
Species:
Human
Synonyms:
CLCN3, Clcn3, clcn3, PTRG_03131, BDBG_05668, MCYG_04420, clcn3.S
Insert length:
2406 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human CLCN3 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Chloride Channel 3 (CLCN3)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4699976
Datasheet
Catalog No. ABIN4699976
Type:
cDNA
Application:
Cloning
Gene:
Chloride Channel 3 (CLCN3)
Species:
Human
Synonyms:
CLCN3, Clcn3, clcn3, PTRG_03131, BDBG_05668, MCYG_04420, clcn3.S
Insert length:
2406 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human CLCN3 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Chloride Channel 3 (CLCN3)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4487484
Datasheet
Catalog No. ABIN4487484
Type:
cDNA
Application:
Protein Expression
Gene:
Chloride Channel 3 (CLCN3)
Species:
Human
Synonyms:
CLCN3, Clcn3, clcn3, PTRG_03131, BDBG_05668, MCYG_04420, clcn3.S
Insert length:
2406 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human CLCN3 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Chloride Channel 3 (CLCN3)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5722442
Datasheet
Catalog No. ABIN5722442
Type:
ORF
Application:
Cloning
Gene:
Chloride Channel 3 (CLCN3)
Species:
Human
Synonyms:
CLCN3, Clcn3, clcn3, PTRG_03131, BDBG_05668, MCYG_04420, clcn3.S
Insert length:
2406 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat CLCN3 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Chloride Channel 3 (CLCN3)
NCBI Accession:
NM_053363
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5086324
Datasheet
Catalog No. ABIN5086324
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Chloride Channel 3 (CLCN3)
NCBI Accession:
NM_053363
Species:
Rat
Synonyms:
CLCN3, Clcn3, clcn3, PTRG_03131, BDBG_05668, MCYG_04420, clcn3.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Clcn3
Format:
Viral Particles
Storage:
-80 °C
Mouse CLCN3 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Chloride Channel 3 (CLCN3)
NCBI Accession:
NM_173873
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5086322
Datasheet
Catalog No. ABIN5086322
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Chloride Channel 3 (CLCN3)
NCBI Accession:
NM_173873
Species:
Mouse
Synonyms:
CLCN3, Clcn3, clcn3, PTRG_03131, BDBG_05668, MCYG_04420, clcn3.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Clcn3
Format:
Viral Particles
Storage:
-80 °C
Human CLCN3 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Chloride Channel 3 (CLCN3)
NCBI Accession:
NM_001829
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5086320
Datasheet
Catalog No. ABIN5086320
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Chloride Channel 3 (CLCN3)
NCBI Accession:
NM_001829
Species:
Human
Synonyms:
CLCN3, Clcn3, clcn3, PTRG_03131, BDBG_05668, MCYG_04420, clcn3.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of CLCN3
Format:
Viral Particles
Storage:
-80 °C
Human CLCN3 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Chloride Channel 3 (CLCN3)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4630954
Datasheet
Catalog No. ABIN4630954
Type:
cDNA
Application:
Cloning
Gene:
Chloride Channel 3 (CLCN3)
Species:
Human
Synonyms:
CLCN3, Clcn3, clcn3, PTRG_03131, BDBG_05668, MCYG_04420, clcn3.S
Insert length:
2406 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human CLCN3 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Chloride Channel 3 (CLCN3)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4422397
Datasheet
Catalog No. ABIN4422397
Type:
cDNA
Application:
Protein Expression
Gene:
Chloride Channel 3 (CLCN3)
Species:
Human
Synonyms:
CLCN3, Clcn3, clcn3, PTRG_03131, BDBG_05668, MCYG_04420, clcn3.S
Insert length:
2406 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse CLCN3 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Chloride Channel 3 (CLCN3)
NCBI Accession:
NM_007711
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5722443
Datasheet
Catalog No. ABIN5722443
Type:
ORF
Application:
Cloning
Gene:
Chloride Channel 3 (CLCN3)
NCBI Accession:
NM_007711
Species:
Mouse
Synonyms:
CLCN3, Clcn3, clcn3, PTRG_03131, BDBG_05668, MCYG_04420, clcn3.S
Insert length:
2283 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pcDNA3.1+C-(K)-DYK
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pRFP-C-RS
    • pCMV6-XL4
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to CLCN3

  • chloride voltage-gated channel 3 (CLCN3)
  • chloride voltage-gated channel 3 (Clcn3)
  • chloride channel, voltage-sensitive 3 (Clcn3)
  • chloride channel 3 (clcn3)
  • chloride channel protein 3 (PTRG_03131)
  • chloride channel protein 3 (BDBG_05668)
  • chloride channel protein 3 (MCYG_04420)
  • chloride channel, voltage-sensitive 3 (clcn3)
  • chloride channel, voltage-sensitive 3 S homeolog (clcn3.S)
  • ClC-3
  • clc-3
  • CLC3
  • Clc3
  • clc3
  • CLCN3
  • fb78c02
  • wu:fb78c02

Gene-IDs for different species

Protein level used designations for CLCN3

  • H(+)/Cl(-) exchange transporter 3
  • chloride channel 3
  • chloride channel protein 3
  • chloride transporter ClC-3
  • protein kinase C-regulated chloride channel
  • clC-3
  • chloride channel Clc-3
  • Chloride channel protein 3
  • H(+)/Cl(-) exchange transporter 3-like
  • putative chloride channel ClC-3
Other products related to CLCN3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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