CLP1 (Cleavage and Polyadenylation Factor I Subunit 1, CLP1)
Short Description: Polynucleotide kinase that can phosphorylate the 5'- hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing\; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA- induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing (By similarity).
More information related to gene CLP1.
More information related to gene CLP1.
Products related to CLP1 Gene:
Recommended next Filters:
60 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Cleavage and Polyadenylation Factor I Subunit 1 (CLP1)
- NCBI Accession:
- NM_006831
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Cleavage and Polyadenylation Factor I Subunit 1 (CLP1)
- NCBI Accession:
- NM_001009599
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Cleavage and Polyadenylation Factor I Subunit 1 (CLP1)
- NCBI Accession:
- NM_133840
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Cleavage and Polyadenylation Factor I Subunit 1 (CLP1)
- NCBI Accession:
- NM_006831
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Cleavage and Polyadenylation Factor I Subunit 1 (CLP1)
- NCBI Accession:
- NM_133840
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Cleavage and Polyadenylation Factor I Subunit 1 (CLP1)
- NCBI Accession:
- NM_001009599
- Species:
- Rat
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Cleavage and Polyadenylation Factor I Subunit 1 (CLP1)
- NCBI Accession:
- NM_001009599
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Cleavage and Polyadenylation Factor I Subunit 1 (CLP1)
- NCBI Accession:
- NM_133840
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Cleavage and Polyadenylation Factor I Subunit 1 (CLP1)
- NCBI Accession:
- NM_006831
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Cleavage and Polyadenylation Factor I Subunit 1 (CLP1)
- NCBI Accession:
- NM_006831
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
Synonyms and alternative names related to CLP1
- cleavage and polyadenylation factor I subunit 1 (Clp1)
- CLP1, cleavage and polyadenylation factor I subunit (Clp1)
- cyclin and CBS domain divalent metal cation transport mediator 1 (CNNM1)
- chitinase 3-like 1 (cartilage glycoprotein-39) (CHI3L1)
- cleavage and polyadenylation factor I subunit 1 (CLP1)
- cleavage and polyadenylation factor I subunit 1 (clp1)
- cleavage and polyadenylation factor I subunit 1 L homeolog (clp1.L)
- ACDP1
- AI462438
- CGP-39
- CLP-1
- clp1
- fa28a12
- GP-39
- hClp1
- Heab
- HEAB
- RGD1307679
- SPC-40
- SPS-40
- wu:fa28a12
- YKL-40
Gene-IDs for different species
Protein level used designations for CLP1
- ATP/GTP-binding protein
- CLP1, cleavage and polyadenylation factor I subunit, homolog
- polyadenylation factor Clp1
- polynucleotide kinase Clp1
- polyribonucleotide 5'-hydroxyl-kinase Clp1
- pre-mRNA cleavage complex II protein Clp1
- ancient conserved domain protein 1
- ancient conserved domain-containing protein 1
- cyclin-M1
- metal transporter CNNM1
- 39 kDa whey protein
- 40 kDa secretory signalling glycoprotein
- cartilage glycoprotein 39
- cartilage glycoprotein-39
- chitinase-3-like protein 1
- chitinase-like protein 1
- signal processing protein
- signal-processing protein
- homolog of yeast CFIA subunit Clp1p
- Polyadenylation factor Clp1
- Polynucleotide kinase Clp1
- Pre-mRNA cleavage complex II protein Clp1
Proteomics products related to CLP1 Gene
Other products related to CLP1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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