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COMT (Catechol-O-Methyltransferase, COMT)

Short Description: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008].
More information related to gene COMT.

Products related to COMT Gene:

86 results :

Human COMT ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Catechol-O-Methyltransferase (COMT)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5739103
Datasheet
Catalog No. ABIN5739103
Type:
ORF
Application:
Cloning
Gene:
Catechol-O-Methyltransferase (COMT)
Species:
Human
Synonyms:
COMT, Comt, MIR4761, comt, comt.2, comt.S, Rv1703c, Mb1729c, comta, comtb, LOC100354142
Insert length:
816 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human COMT ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Catechol-O-Methyltransferase (COMT)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5739104
Datasheet
Catalog No. ABIN5739104
Type:
ORF
Application:
Cloning
Gene:
Catechol-O-Methyltransferase (COMT)
Species:
Human
Synonyms:
COMT, Comt, MIR4761, comt, comt.2, comt.S, Rv1703c, Mb1729c, comta, comtb, LOC100354142
Insert length:
549 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat COMT ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Catechol-O-Methyltransferase (COMT)
NCBI Accession:
NM_012531
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5739108
Datasheet
Catalog No. ABIN5739108
Type:
ORF
Application:
Cloning
Gene:
Catechol-O-Methyltransferase (COMT)
NCBI Accession:
NM_012531
Species:
Rat
Synonyms:
COMT, Comt, MIR4761, comt, comt.2, comt.S, Rv1703c, Mb1729c, comta, comtb, LOC100354142
Insert length:
795 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat COMT cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Catechol-O-Methyltransferase (COMT)
NCBI Accession:
NM_012531
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4430098
Datasheet
Catalog No. ABIN4430098
Type:
cDNA
Application:
Protein Expression
Gene:
Catechol-O-Methyltransferase (COMT)
NCBI Accession:
NM_012531
Species:
Rat
Synonyms:
COMT, Comt, MIR4761, comt, comt.2, comt.S, Rv1703c, Mb1729c, comta, comtb, LOC100354142
Insert length:
795 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human COMT cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Catechol-O-Methyltransferase (COMT)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4474173
Datasheet
Catalog No. ABIN4474173
Type:
cDNA
Application:
Protein Expression
Gene:
Catechol-O-Methyltransferase (COMT)
Species:
Human
Synonyms:
COMT, Comt, MIR4761, comt, comt.2, comt.S, Rv1703c, Mb1729c, comta, comtb, LOC100354142
Insert length:
816 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human COMT cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Catechol-O-Methyltransferase (COMT)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4474174
Datasheet
Catalog No. ABIN4474174
Type:
cDNA
Application:
Protein Expression
Gene:
Catechol-O-Methyltransferase (COMT)
Species:
Human
Synonyms:
COMT, Comt, MIR4761, comt, comt.2, comt.S, Rv1703c, Mb1729c, comta, comtb, LOC100354142
Insert length:
816 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat COMT CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Catechol-O-Methyltransferase (COMT)
NCBI Accession:
NM_012531
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5116176
Datasheet
Catalog No. ABIN5116176
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Catechol-O-Methyltransferase (COMT)
NCBI Accession:
NM_012531
Species:
Rat
Synonyms:
COMT, Comt, MIR4761, comt, comt.2, comt.S, Rv1703c, Mb1729c, comta, comtb, LOC100354142
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Comt
Format:
Viral Particles
Storage:
-80 °C
Mouse COMT CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Catechol-O-Methyltransferase (COMT)
NCBI Accession:
NM_007744
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5116174
Datasheet
Catalog No. ABIN5116174
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Catechol-O-Methyltransferase (COMT)
NCBI Accession:
NM_007744
Species:
Mouse
Synonyms:
COMT, Comt, MIR4761, comt, comt.2, comt.S, Rv1703c, Mb1729c, comta, comtb, LOC100354142
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Comt
Format:
Viral Particles
Storage:
-80 °C
Human COMT CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Catechol-O-Methyltransferase (COMT)
NCBI Accession:
NM_007310
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5116172
Datasheet
Catalog No. ABIN5116172
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Catechol-O-Methyltransferase (COMT)
NCBI Accession:
NM_007310
Species:
Human
Synonyms:
COMT, Comt, MIR4761, comt, comt.2, comt.S, Rv1703c, Mb1729c, comta, comtb, LOC100354142
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of COMT
Format:
Viral Particles
Storage:
-80 °C
Human COMT cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Catechol-O-Methyltransferase (COMT)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4760549
Datasheet
Catalog No. ABIN4760549
Type:
cDNA
Application:
Cloning
Gene:
Catechol-O-Methyltransferase (COMT)
Species:
Human
Synonyms:
COMT, Comt, MIR4761, comt, comt.2, comt.S, Rv1703c, Mb1729c, comta, comtb, LOC100354142
Insert length:
816 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-AC
    • pCas-Guide
    • pDONR223
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL5
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to COMT

  • catechol-O-methyltransferase (COMT)
  • catechol-O-methyltransferase (Comt)
  • microRNA 4761 (MIR4761)
  • catechol-O-methyltransferase (comt)
  • catechol-O-methyltransferase (comt.2)
  • catechol-O-methyltransferase S homeolog (comt.S)
  • methyltransferase (Rv1703c)
  • catechol-o-methyltransferase (Mb1729c)
  • catechol-O-methyltransferase a (comta)
  • catechol-O-methyltransferase b (comtb)
  • catechol O-methyltransferase (LOC100354142)
  • COMT
  • comt
  • Comt1
  • D16Wsu103e
  • D330014B15Rik
  • mb-comt
  • MGC154444
  • s-comt
  • si:dkey-13a21.15
  • zgc:114157
  • zgc:162236
  • zK13A21.15

Gene-IDs for different species

Protein level used designations for COMT

  • catechol O-methyltransferase
  • catechol-O-methyltransferase 1
  • catecholamine-O-methyltransferase
  • catechol-O-methyltransferase
  • O-methyltransferase
  • catechol-o-methyltransferase
  • catechol O-methyltransferase, soluble form
  • catechol O-methyltransferase, membrane-bound form
  • catechol-O-methyltransferase a
Other products related to COMT such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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