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CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4, CTLA4)

Short Description: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008].
More information related to gene CTLA4.

Products related to CTLA4 Gene:

71 results :

Human CTLA4 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
NCBI Accession:
NM_005214
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5738736
Datasheet
Catalog No. ABIN5738736
Type:
ORF
Application:
Cloning
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
NCBI Accession:
NM_005214
Species:
Human
Synonyms:
CTLA4, Ctla4
Insert length:
672 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse CTLA4 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
NCBI Accession:
NM_009843
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5738737
Datasheet
Catalog No. ABIN5738737
Type:
ORF
Application:
Cloning
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
NCBI Accession:
NM_009843
Species:
Mouse
Synonyms:
CTLA4, Ctla4
Insert length:
672 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human CTLA4 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
NCBI Accession:
NM_005214
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4487619
Datasheet
Catalog No. ABIN4487619
Type:
cDNA
Application:
Protein Expression
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
NCBI Accession:
NM_005214
Species:
Human
Synonyms:
CTLA4, Ctla4
Insert length:
672 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse CTLA4 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
NCBI Accession:
NM_009843
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4441011
Datasheet
Catalog No. ABIN4441011
Type:
cDNA
Application:
Protein Expression
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
NCBI Accession:
NM_009843
Species:
Mouse
Synonyms:
CTLA4, Ctla4
Insert length:
672 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human CTLA4 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5230834
Datasheet
Catalog No. ABIN5230834
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
Species:
Human
Synonyms:
CTLA4, Ctla4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of IDDM12
Format:
Viral Particles
Storage:
-80 °C
Mouse CTLA4 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
NCBI Accession:
NM_009843
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5230830
Datasheet
Catalog No. ABIN5230830
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
NCBI Accession:
NM_009843
Species:
Mouse
Synonyms:
CTLA4, Ctla4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ctla4
Format:
Viral Particles
Storage:
-80 °C
Mouse CTLA4 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
NCBI Accession:
NM_009843
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5230829
Datasheet
Catalog No. ABIN5230829
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
NCBI Accession:
NM_009843
Species:
Mouse
Synonyms:
CTLA4, Ctla4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ctla4
Format:
Viral Particles
Storage:
-80 °C
Rat CTLA4 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
NCBI Accession:
NM_031674
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5230832
Datasheet
Catalog No. ABIN5230832
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
NCBI Accession:
NM_031674
Species:
Rat
Synonyms:
CTLA4, Ctla4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ctla4
Format:
Viral Particles
Storage:
-80 °C
Mouse CTLA4 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
NCBI Accession:
NM_009843
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5230828
Datasheet
Catalog No. ABIN5230828
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
NCBI Accession:
NM_009843
Species:
Mouse
Synonyms:
CTLA4, Ctla4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ctla4
Format:
Viral Particles
Storage:
-80 °C
Human CTLA4 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
NCBI Accession:
NM_005214
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5230826
Datasheet
Catalog No. ABIN5230826
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
NCBI Accession:
NM_005214
Species:
Human
Synonyms:
CTLA4, Ctla4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of CTLA4
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-U6-sgRNA-PGK-Neo
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCMV6-XL6
    • pCas-Guide
    • pcDNA3.1+C-(K)-DYK
    • pRFP-C-RS
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • SFFV Promoter
    • T7 Promoter
    • PGK Promoter
    • Enhanced CMV Promoter
    • SP6 Promoter
  • Format
    • Lyophilized
    • Viral Particles
    • Liquid

Synonyms and alternative names related to CTLA4

  • cytotoxic T-lymphocyte associated protein 4 (CTLA4)
  • cytotoxic T-lymphocyte-associated protein 4 (Ctla4)
  • CD
  • CD152
  • Cd152
  • CELIAC3
  • CTLA-4
  • Ctla-4
  • CTLA4
  • GRD4
  • GSE
  • IDDM12
  • Ly-56
  • sCTLA4

Gene-IDs for different species

Protein level used designations for CTLA4

  • cytotoxic T-lymphocyte-associated protein 4 precursor
  • CD152 protein
  • cytotoxic T-lymphocyte protein 4
  • cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM
  • cytotoxic T-lymphocyte-associated protein 4
  • costimulatory molecule B7 receptor
  • cytotoxic T lymphocyte-associated antigen 4
  • CD152 antigen
  • cytotoxic T-lymphocyte-associated antigen 4
  • CD152 isoform
  • celiac disease 3
  • cytotoxic T lymphocyte associated antigen 4 short spliced form
  • cytotoxic T-lymphocyte antigen 4
  • cytotoxic T-lymphocyte-associated serine esterase-4
  • ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
  • soluble form
  • transmembrane form
  • CTLA-4
  • cytotoxic T lymphocyte-associated protein 4
  • costimulatory molecule B7 receptor CD152
Other products related to CTLA4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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