CYP27B1 (Cytochrome P450, Family 27, Subfamily B, Polypeptide 1, CYP27B1)
Short Description: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I. [provided by RefSeq, Jul 2008].
More information related to gene CYP27B1.
More information related to gene CYP27B1.
Products related to CYP27B1 Gene:
Recommended next Filters:
58 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1)
- NCBI Accession:
- NM_010009
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1)
- NCBI Accession:
- NM_053763
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1)
- NCBI Accession:
- NM_000785
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1)
- NCBI Accession:
- NM_053763
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1)
- NCBI Accession:
- NM_010009
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1)
- NCBI Accession:
- NM_000785
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
Synonyms and alternative names related to CYP27B1
- cytochrome P450 family 27 subfamily B member 1 (cyp27b1)
- cytochrome P450 family 27 subfamily B member 1 (CYP27B1)
- cytochrome P450, family 27, subfamily B, polypeptide 1 (CYP27B1)
- cytochrome P450, family 27, subfamily b, polypeptide 1 (Cyp27b1)
- cp2b
- CP2B
- Cp2b
- cyp1
- CYP1
- Cyp1
- cyp1alpha
- CYP1alpha
- cyp27b
- CYP27B
- Cyp27b
- Cyp40
- p450c1
- P450c1
- pddr
- PDDR
- Pddr
- vdd1
- VDD1
- Vdd1
- vddr
- VDDR
- Vddr
- vddri
- VDDRI
- VddrI
- vdr
- VDR
- Vdr
Gene-IDs for different species
Protein level used designations for CYP27B1
- cytochrome P450, family 27, subfamily B, polypeptide 1
- 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial
- mitochondrial 25 hydroxyvitamin D3-1alpha-hydroxylase
- 1alpha(OH)ase
- 25 hydroxyvitamin D3-1-alpha hydroxylase
- 25-OHD-1 alpha-hydroxylase
- VD3 1A hydroxylase
- calcidiol 1-monooxygenase
- cytochrome P450 subfamily XXVIIB polypeptide 1
- cytochrome P450C1 alpha
- cytochrome P450VD1-alpha
- cytochrome p450 27B1
- 25-hydroxyvitamin D(3) 1-alpha-hydroxylase
- P450C1 alpha
- P450VD1-alpha
- cytochrome P450 40 (25-hydroxyvitamin D3 1 alpha-hydroxylase)
- cytochrome P450 subfamily XXVIIB (25-hydroxyvitamin D-1-alpha-hydroxylase) polypeptide 1
- cytochrome P450, 40 (25-hydroxyvitamin D3 1 alpha-hydroxylase)
- cytochrome P450, subfamily 27b, polypeptide 1
- 25(OH)D 1alpha-hydroxylase
- 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial precursor (25-OHD-1 alpha-hydroxylase) (25-hydroxyvitamin D3 1-alpha-hydroxylase) (VD3 1A hydroxylase) (P450C1 alpha) (P450VD1-alpha)
- 25-hydroxyvitamin D3 1alpha-hydroxylase
- P450VD1alpha
- cytochrome P450, 27b1
Proteomics products related to CYP27B1 Gene
Other products related to CYP27B1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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