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CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1, CYP46A1)

Short Description: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008].
More information related to gene CYP46A1.

Products related to CYP46A1 Gene:

55 results :

Human CYP46A1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4829860
Datasheet
Catalog No. ABIN4829860
Type:
cDNA
Application:
Cloning
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
Species:
Human
Synonyms:
CYP46A1, cyp46a1.L, cyp46a1.1, cyp46a1, PTRG_08343, PTRG_09667, Cyp46a1, Sgly_1093
Insert length:
1503 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human CYP46A1 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4700731
Datasheet
Catalog No. ABIN4700731
Type:
cDNA
Application:
Cloning
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
Species:
Human
Synonyms:
CYP46A1, cyp46a1.L, cyp46a1.1, cyp46a1, PTRG_08343, PTRG_09667, Cyp46a1, Sgly_1093
Insert length:
1503 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human CYP46A1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4487658
Datasheet
Catalog No. ABIN4487658
Type:
cDNA
Application:
Protein Expression
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
Species:
Human
Synonyms:
CYP46A1, cyp46a1.L, cyp46a1.1, cyp46a1, PTRG_08343, PTRG_09667, Cyp46a1, Sgly_1093
Insert length:
1503 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human CYP46A1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5739388
Datasheet
Catalog No. ABIN5739388
Type:
ORF
Application:
Cloning
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
Species:
Human
Synonyms:
CYP46A1, cyp46a1.L, cyp46a1.1, cyp46a1, PTRG_08343, PTRG_09667, Cyp46a1, Sgly_1093
Insert length:
1503 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat CYP46A1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
NCBI Accession:
NM_001108723
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5232080
Datasheet
Catalog No. ABIN5232080
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
NCBI Accession:
NM_001108723
Species:
Rat
Synonyms:
CYP46A1, cyp46a1.L, cyp46a1.1, cyp46a1, PTRG_08343, PTRG_09667, Cyp46a1, Sgly_1093
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cyp46a1
Format:
Viral Particles
Storage:
-80 °C
Mouse CYP46A1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
NCBI Accession:
NM_010010
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5232078
Datasheet
Catalog No. ABIN5232078
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
NCBI Accession:
NM_010010
Species:
Mouse
Synonyms:
CYP46A1, cyp46a1.L, cyp46a1.1, cyp46a1, PTRG_08343, PTRG_09667, Cyp46a1, Sgly_1093
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cyp46a1
Format:
Viral Particles
Storage:
-80 °C
Human CYP46A1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
NCBI Accession:
NM_006668
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5232076
Datasheet
Catalog No. ABIN5232076
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
NCBI Accession:
NM_006668
Species:
Human
Synonyms:
CYP46A1, cyp46a1.L, cyp46a1.1, cyp46a1, PTRG_08343, PTRG_09667, Cyp46a1, Sgly_1093
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of CYP46A1
Format:
Viral Particles
Storage:
-80 °C
Rat CYP46A1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
NCBI Accession:
NM_001108723
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5116726
Datasheet
Catalog No. ABIN5116726
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
NCBI Accession:
NM_001108723
Species:
Rat
Synonyms:
CYP46A1, cyp46a1.L, cyp46a1.1, cyp46a1, PTRG_08343, PTRG_09667, Cyp46a1, Sgly_1093
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cyp46a1
Format:
Viral Particles
Storage:
-80 °C
Mouse CYP46A1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
NCBI Accession:
NM_010010
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5116724
Datasheet
Catalog No. ABIN5116724
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
NCBI Accession:
NM_010010
Species:
Mouse
Synonyms:
CYP46A1, cyp46a1.L, cyp46a1.1, cyp46a1, PTRG_08343, PTRG_09667, Cyp46a1, Sgly_1093
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cyp46a1
Format:
Viral Particles
Storage:
-80 °C
Human CYP46A1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
NCBI Accession:
NM_006668
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5116722
Datasheet
Catalog No. ABIN5116722
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1)
NCBI Accession:
NM_006668
Species:
Human
Synonyms:
CYP46A1, cyp46a1.L, cyp46a1.1, cyp46a1, PTRG_08343, PTRG_09667, Cyp46a1, Sgly_1093
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of CYP46A1
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pCMV6-AC-GFP
    • pCMV6-XL4
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to CYP46A1

  • cytochrome P450 family 46 subfamily A member 1 (CYP46A1)
  • cytochrome P450 family 46 subfamily A member 1 L homeolog (cyp46a1.L)
  • cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1 (cyp46a1.1)
  • cytochrome P450, family 46 (cyp46a1)
  • cytochrome P450 46A1 (PTRG_08343)
  • cytochrome P450 46A1 (PTRG_09667)
  • cytochrome P450, family 46, subfamily a, polypeptide 1 (Cyp46a1)
  • cholesterol 24-hydroxylase (Sgly_1093)
  • cytochrome P450, family 46, subfamily A, polypeptide 1 (CYP46A1)
  • CP46
  • CYP46
  • Cyp46
  • CYP46A1
  • MGC147389
  • zgc:109896

Gene-IDs for different species

Protein level used designations for CYP46A1

  • CH24H
  • cholesterol 24-hydroxylase
  • cytochrome P450 46A1
  • cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)
  • cytochrome P450, family 46, subfamily A, polypeptide 1
  • cytochrome P450, family 46
  • cholestrol 24-hydroxylase
  • cytochrome P450, 46 (cholesterol 24-hydroxylase)
  • cytochrome P450, 46a1 (cholesterol 24-hydroxylase)
  • cholesterol-24S-hydroxylase
Other products related to CYP46A1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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