Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@genomics-online.com

DIO1 (Deiodinase, Iodothyronine, Type I, DIO1)

Short Description: The protein encoded by this gene is a thiol-requiring propylthiouracil-sensitive oxidoreductase. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It also degrades both hormones by inner ring deiodination (IRD). Alternative splicing results in multiple transcript variants encoding different isoforms. Some, but not all, isoforms contain a selenocysteine (Sec) residue encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Additional transcript variants have been described but are not supported by experimental evidence. [provided by RefSeq, Jul 2008].
More information related to gene DIO1.

Products related to DIO1 Gene:

64 results :

Human DIO1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5736503
Datasheet
Catalog No. ABIN5736503
Type:
ORF
Application:
Cloning
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
Species:
Human
Synonyms:
DIO1, LOC100231867, Dio1, dio1.L, dio1
Insert length:
750 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat DIO1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
NCBI Accession:
NM_021653
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5111217
Datasheet
Catalog No. ABIN5111217
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
NCBI Accession:
NM_021653
Species:
Rat
Synonyms:
DIO1, LOC100231867, Dio1, dio1.L, dio1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dio1
Format:
Viral Particles
Storage:
-80 °C
Mouse DIO1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
NCBI Accession:
NM_007860
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5111215
Datasheet
Catalog No. ABIN5111215
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
NCBI Accession:
NM_007860
Species:
Mouse
Synonyms:
DIO1, LOC100231867, Dio1, dio1.L, dio1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dio1
Format:
Viral Particles
Storage:
-80 °C
Human DIO1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
NCBI Accession:
NM_001039715
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5111213
Datasheet
Catalog No. ABIN5111213
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
NCBI Accession:
NM_001039715
Species:
Human
Synonyms:
DIO1, LOC100231867, Dio1, dio1.L, dio1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of DIO1
Format:
Viral Particles
Storage:
-80 °C
Mouse DIO1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
NCBI Accession:
NM_007860
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5736504
Datasheet
Catalog No. ABIN5736504
Type:
ORF
Application:
Cloning
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
NCBI Accession:
NM_007860
Species:
Mouse
Synonyms:
DIO1, LOC100231867, Dio1, dio1.L, dio1
Insert length:
774 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat DIO1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
NCBI Accession:
NM_021653
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5736505
Datasheet
Catalog No. ABIN5736505
Type:
ORF
Application:
Cloning
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
NCBI Accession:
NM_021653
Species:
Rat
Synonyms:
DIO1, LOC100231867, Dio1, dio1.L, dio1
Insert length:
774 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat DIO1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
NCBI Accession:
NM_021653
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5226528
Datasheet
Catalog No. ABIN5226528
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
NCBI Accession:
NM_021653
Species:
Rat
Synonyms:
DIO1, LOC100231867, Dio1, dio1.L, dio1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dio1
Format:
Viral Particles
Storage:
-80 °C
Human DIO1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
NCBI Accession:
NM_001039715
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5226524
Datasheet
Catalog No. ABIN5226524
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
NCBI Accession:
NM_001039715
Species:
Human
Synonyms:
DIO1, LOC100231867, Dio1, dio1.L, dio1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of DIO1
Format:
Viral Particles
Storage:
-80 °C
Mouse DIO1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
NCBI Accession:
NM_007860
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5226526
Datasheet
Catalog No. ABIN5226526
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
NCBI Accession:
NM_007860
Species:
Mouse
Synonyms:
DIO1, LOC100231867, Dio1, dio1.L, dio1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dio1
Format:
Viral Particles
Storage:
-80 °C
Human DIO1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4484416
Datasheet
Catalog No. ABIN4484416
Type:
cDNA
Application:
Protein Expression
Gene:
Deiodinase, Iodothyronine, Type I (DIO1)
Species:
Human
Synonyms:
DIO1, LOC100231867, Dio1, dio1.L, dio1
Insert length:
750 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pRFP-C-RS
    • pCMV6-XL5
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to DIO1

  • iodothyronine deiodinase 1 (DIO1)
  • type I iodothyronine deiodinase-like (LOC100231867)
  • deiodinase, iodothyronine, type I (Dio1)
  • deiodinase, iodothyronine type 1 L homeolog (dio1.L)
  • iodothyronine deiodinase 1 (dio1)
  • 5DI
  • cb685
  • D1
  • Deio1
  • DIOI
  • ITDI1
  • TXDI1
  • zgc:92323

Gene-IDs for different species

Protein level used designations for DIO1

  • DIOI
  • thyroxine deiodinase type I (selenoprotein)
  • type 1 DI
  • type I iodothyronine deiodinase
  • type-I 5'-deiodinase
  • thyroxine deiodinase, type I
  • 5DI
  • thyroxine deiodinase type 1
  • Type 1 DI
  • Type-I 5'-deiodinase
  • deiodinase, iodothyronine, type I
  • type 1 deiodinase
Other products related to DIO1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
You are here:

antibodies-online

german

german (deutsch) antikoerper-online.de

english

english (english) antibodies-online.com

french

french (français) anticorps-enligne.fr

chinese

chinese (中文) antibodies-online.cn

genomics-online

english

english (english) genomics-online.com

Support