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DOT1L (DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae), DOT1L)

Short Description: The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011].
More information related to gene DOT1L.

Products related to DOT1L Gene:

56 results :

Rat DOT1L CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_001108733
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5233398
Datasheet
Catalog No. ABIN5233398
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_001108733
Species:
Rat
Synonyms:
LOC100116648, DOT1L, DOT1, Dot1l
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dot1l
Format:
Viral Particles
Storage:
-80 °C
Mouse DOT1L CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_199322
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5233396
Datasheet
Catalog No. ABIN5233396
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_199322
Species:
Mouse
Synonyms:
LOC100116648, DOT1L, DOT1, Dot1l
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dot1l
Format:
Viral Particles
Storage:
-80 °C
Mouse DOT1L CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_007722
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5233394
Datasheet
Catalog No. ABIN5233394
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_007722
Species:
Mouse
Synonyms:
LOC100116648, DOT1L, DOT1, Dot1l
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dot1L
Format:
Viral Particles
Storage:
-80 °C
Human DOT1L CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_032482
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5233392
Datasheet
Catalog No. ABIN5233392
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_032482
Species:
Human
Synonyms:
LOC100116648, DOT1L, DOT1, Dot1l
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of DOT1L
Format:
Viral Particles
Storage:
-80 °C
Mouse DOT1L CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_199322
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5118036
Datasheet
Catalog No. ABIN5118036
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_199322
Species:
Mouse
Synonyms:
LOC100116648, DOT1L, DOT1, Dot1l
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dot1l
Format:
Viral Particles
Storage:
-80 °C
Rat DOT1L CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_001108733
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5118038
Datasheet
Catalog No. ABIN5118038
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_001108733
Species:
Rat
Synonyms:
LOC100116648, DOT1L, DOT1, Dot1l
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dot1l
Format:
Viral Particles
Storage:
-80 °C
Human DOT1L CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_032482
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5118032
Datasheet
Catalog No. ABIN5118032
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_032482
Species:
Human
Synonyms:
LOC100116648, DOT1L, DOT1, Dot1l
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of DOT1L
Format:
Viral Particles
Storage:
-80 °C
Mouse DOT1L CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_007722
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5118034
Datasheet
Catalog No. ABIN5118034
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_007722
Species:
Mouse
Synonyms:
LOC100116648, DOT1L, DOT1, Dot1l
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dot1L
Format:
Viral Particles
Storage:
-80 °C
Rat DOT1L CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_001108733
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5233397
Datasheet
Catalog No. ABIN5233397
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_001108733
Species:
Rat
Synonyms:
LOC100116648, DOT1L, DOT1, Dot1l
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Dot1l
Format:
Viral Particles
Storage:
-80 °C
Mouse DOT1L CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_199322
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5233395
Datasheet
Catalog No. ABIN5233395
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)
NCBI Accession:
NM_199322
Species:
Mouse
Synonyms:
LOC100116648, DOT1L, DOT1, Dot1l
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Dot1l
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
  • Reactivity
    • Mouse
    • Human
    • Rat
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pORF
    • pRFP-C-RS
    • pCMV6-AC-GFP
    • pCMV6-XL4
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
    • ORF
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to DOT1L

  • histone-lysine N-methyltransferase, H3 lysine-79 specific (LOC100116648)
  • DOT1 like histone lysine methyltransferase (DOT1L)
  • histone methyltransferase (DOT1)
  • DOT1 like histone lysine methyltransferase (Dot1l)
  • DOT1-like, histone H3 methyltransferase (S. cerevisiae) (Dot1l)
  • A630076O07
  • AW907654
  • DOT1
  • Dot1
  • DOT1L
  • KMT4
  • mDot1
  • NV11307

Gene-IDs for different species

Protein level used designations for DOT1L

  • histone-lysine N-methyltransferase, H3 lysine-79 specific
  • DOT1-like, histone H3 methyltransferase (S. cerevisiae)
  • histone-lysine N-methyltransferase, H3 lysine-79 specific-like
  • possible nucleosomal histone methylase
  • DOT1-like protein
  • DOT1-like, histone H3 methyltransferase
  • H3-K79-HMTase
  • histone H3-K79 methyltransferase
  • histone methyltransferase DOT1L
  • lysine N-methyltransferase 4
  • DOT1-like histone H3 methyltransferase
  • histone H3 methyltransferase DOT1
Other products related to DOT1L such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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