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EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1, EGLN1)

Short Description: The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). [provided by RefSeq, Nov 2009].
More information related to gene EGLN1.

Products related to EGLN1 Gene:

43 results :

Human EGLN1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4475050
Datasheet
Catalog No. ABIN4475050
Type:
cDNA
Application:
Protein Expression
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
Species:
Human
Synonyms:
EGLN1, egln1.S, egln1b, Egln1
Insert length:
387 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse EGLN1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
NCBI Accession:
NM_053207
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5234150
Datasheet
Catalog No. ABIN5234150
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
NCBI Accession:
NM_053207
Species:
Mouse
Synonyms:
EGLN1, egln1.S, egln1b, Egln1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Egln1
Format:
Viral Particles
Storage:
-80 °C
Human EGLN1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
NCBI Accession:
NM_022051
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5234148
Datasheet
Catalog No. ABIN5234148
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
NCBI Accession:
NM_022051
Species:
Human
Synonyms:
EGLN1, egln1.S, egln1b, Egln1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of EGLN1
Format:
Viral Particles
Storage:
-80 °C
Mouse EGLN1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
NCBI Accession:
NM_053207
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5118792
Datasheet
Catalog No. ABIN5118792
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
NCBI Accession:
NM_053207
Species:
Mouse
Synonyms:
EGLN1, egln1.S, egln1b, Egln1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Egln1
Format:
Viral Particles
Storage:
-80 °C
Human EGLN1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
NCBI Accession:
NM_022051
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5118790
Datasheet
Catalog No. ABIN5118790
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
NCBI Accession:
NM_022051
Species:
Human
Synonyms:
EGLN1, egln1.S, egln1b, Egln1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of EGLN1
Format:
Viral Particles
Storage:
-80 °C
Human EGLN1 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4761425
Datasheet
Catalog No. ABIN4761425
Type:
cDNA
Application:
Cloning
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
Species:
Human
Synonyms:
EGLN1, egln1.S, egln1b, Egln1
Insert length:
387 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human EGLN1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4830660
Datasheet
Catalog No. ABIN4830660
Type:
cDNA
Application:
Cloning
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
Species:
Human
Synonyms:
EGLN1, egln1.S, egln1b, Egln1
Insert length:
387 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human EGLN1 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4701531
Datasheet
Catalog No. ABIN4701531
Type:
cDNA
Application:
Cloning
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
Species:
Human
Synonyms:
EGLN1, egln1.S, egln1b, Egln1
Insert length:
387 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human EGLN1 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4436145
Datasheet
Catalog No. ABIN4436145
Type:
cDNA
Application:
Protein Expression
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
Species:
Human
Synonyms:
EGLN1, egln1.S, egln1b, Egln1
Insert length:
387 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse EGLN1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
NCBI Accession:
NM_053207
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4442519
Datasheet
Catalog No. ABIN4442519
Type:
cDNA
Application:
Protein Expression
Gene:
Egl Nine Homolog 1 (C. Elegans) (EGLN1)
NCBI Accession:
NM_053207
Species:
Mouse
Synonyms:
EGLN1, egln1.S, egln1b, Egln1
Insert length:
1203 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-Entry
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pCMV6-AC-GFP
    • pCMV6-XL6
    • pDONR223
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Retroviral Vector
    • Bacterial Expression Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • shRNA
    • ORF
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
    • SP6 Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to EGLN1

  • egl nine homolog 1 (C. elegans) (EGLN1)
  • egl-9 family hypoxia inducible factor 1 (EGLN1)
  • egl-9 family hypoxia-inducible factor 1 S homeolog (egln1.S)
  • egl-9 family hypoxia-inducible factor 1b (egln1b)
  • egl-9 family hypoxia-inducible factor 1 (Egln1)
  • AI503754
  • C1orf12
  • ECYT3
  • EGLN1
  • egln2
  • Hif-p4h-2
  • HIF-PH2
  • HIFPH2
  • HPH-2
  • HPH2
  • ORF13
  • PHD-2
  • phd2
  • Phd2
  • PHD2
  • SM-20
  • SM20
  • zgc:92314
  • ZMYND6

Gene-IDs for different species

Protein level used designations for EGLN1

  • egl nine homolog 1 (C. elegans)
  • egl nine homolog 1
  • egl nine homolog 1-like
  • egl nine homolog 2
  • Hif-p4h-2
  • HIF-prolyl hydroxylase 2
  • hypoxia-inducible factor prolyl hydroxylase 2
  • prolyl hydroxylase domain-containing protein 2
  • HIF prolyl hydroxylase 2
  • egl nine-like protein 1
  • zinc finger MYND domain-containing protein 6
Other products related to EGLN1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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