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EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E, EIF3E)

Short Description: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins. {ECO:0000255|HAMAP-Rule:MF_03004}.
More information related to gene EIF3E.

Products related to EIF3E Gene:

76 results :

ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5723358
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5723355
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5723356
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5723357
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4475082
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4475083
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4475084
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4475094
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E)
NCBI Accession:
NM_001011990
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5087948
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E)
NCBI Accession:
NM_008388
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5087946
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • ProteoGenix
    • GenScript
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • His tag
    • GFP tag
    • HA tag
    • Myc-DYKDDDDK Tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pPB-His-GST
    • pPB-His-MBP
    • pDONR223
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC
    • pCMV6-AC-GFP
    • pCMV6-XL6
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Spectinomycin
    • Chloramphenicol
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
    • SP6 Promoter
  • Format
    • Liquid
    • Lyophilized
    • Viral Particles

Synonyms and alternative names related to EIF3E

  • eukaryotic translation initiation factor 3 subunit E (EIF3E)
  • eukaryotic translation initiation factor 3, subunit E (Eif3e)
  • eukaryotic translation initiation factor 3 subunit E (eif3e)
  • eukaryotic translation initiation factor 3 subunit E L homeolog (eif3e.L)
  • eukaryotic translation initiation factor 3 subunit 6 (LOC692936)
  • eukaryotic translation initiation factor 3 subunit E S homeolog (eif3e.S)
  • eukaryotic translation initiation factor 3, subunit E, a (eif3ea)
  • Eukaryotic translation initiation factor 3 subunit E (eif-3.E)
  • eukaryotic translation initiation factor 3, subunit E, b (eif3eb)
  • eukaryotic translation initiation factor 3 subunit E (Eif3e)
  • eukaryotic translation initiation factor 3 subunit E (LOC108348260)
  • eukaryotic translation initiation factor 3 subunit E (int6)
  • 48kDa
  • eIF3-p46
  • EIF3-P48
  • eIF3-p48
  • eif3-p48
  • eIF3-S6
  • eIF3e
  • EIF3S6
  • Eif3s6
  • eif3s6
  • eif3s6-A
  • eif3s6-B
  • eif3s6b
  • EIF3SE
  • im:7147439
  • INT6
  • Int6
  • QtsA-18056

Gene-IDs for different species

Protein level used designations for EIF3E

  • eIF-3 p48
  • eukaryotic translation initiation factor 3 subunit 6
  • eukaryotic translation initiation factor 3 subunit E
  • eukaryotic translation initiation factor 3, subunit 6 (48kD)
  • eukaryotic translation initiation factor 3, subunit 6 48kDa
  • mammary tumor-associated protein INT6
  • murine mammary tumor integration site 6 (oncogene homolog)
  • viral integration site protein INT-6 homolog
  • MMTV integration site 6
  • mammary tumor integration site 6
  • mammary tumor-associated protein INT-6
  • viral integration site protein INT-6
  • eukaryotic translation initiation factor 3, subunit 6
  • eukaryotic translation initiation factor 3 subunit E-A
  • Eukaryotic translation initiation factor 3 subunit 6-A
  • eukaryotic translation initiation factor 3 subunit E-B
  • Eukaryotic translation initiation factor 3 subunit 6-B
  • eukaryotic translation initiation factor 3, subunit E
  • Eukaryotic translation initiation factor 3 subunit 6
  • eukaryotic translation initiation factor 3 subunit E-like
  • eIF3e-B
  • eukaryotic translation initiation factor 3 subunit 6-B
  • eukaryotic translation initiation factor 3, subunit 6b
Other products related to EIF3E such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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