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FAS (TNF Receptor Superfamily, Member 6, FAS)

Short Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. [provided by RefSeq, Mar 2011].
More information related to gene FAS.

Products related to FAS Gene:

74 results :

Human FAS ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5740600
Datasheet
Catalog No. ABIN5740600
Type:
ORF
Application:
Cloning
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
Species:
Human
Synonyms:
FAS, Fas, fas
Insert length:
1008 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse FAS ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NM_007987
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5740601
Datasheet
Catalog No. ABIN5740601
Type:
ORF
Application:
Cloning
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NM_007987
Species:
Mouse
Synonyms:
FAS, Fas, fas
Insert length:
984 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human FAS cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4475543
Datasheet
Catalog No. ABIN4475543
Type:
cDNA
Application:
Protein Expression
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
Species:
Human
Synonyms:
FAS, Fas, fas
Insert length:
1008 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse FAS cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NM_007987
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4443392
Datasheet
Catalog No. ABIN4443392
Type:
cDNA
Application:
Protein Expression
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NM_007987
Species:
Mouse
Synonyms:
FAS, Fas, fas
Insert length:
984 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat FAS CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NM_139194
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5118976
Datasheet
Catalog No. ABIN5118976
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NM_139194
Species:
Rat
Synonyms:
FAS, Fas, fas
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Fas
Format:
Viral Particles
Storage:
-80 °C
Mouse FAS CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NM_007987
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5118974
Datasheet
Catalog No. ABIN5118974
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NM_007987
Species:
Mouse
Synonyms:
FAS, Fas, fas
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Fas
Format:
Viral Particles
Storage:
-80 °C
Human FAS CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NM_000043
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5118972
Datasheet
Catalog No. ABIN5118972
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NM_000043
Species:
Human
Synonyms:
FAS, Fas, fas
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of FAS
Format:
Viral Particles
Storage:
-80 °C
Human FAS cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4761918
Datasheet
Catalog No. ABIN4761918
Type:
cDNA
Application:
Cloning
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
Species:
Human
Synonyms:
FAS, Fas, fas
Insert length:
1008 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human FAS cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4831384
Datasheet
Catalog No. ABIN4831384
Type:
cDNA
Application:
Cloning
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
Species:
Human
Synonyms:
FAS, Fas, fas
Insert length:
1008 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse FAS cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NM_007987
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4642709
Datasheet
Catalog No. ABIN4642709
Type:
cDNA
Application:
Cloning
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NM_007987
Species:
Mouse
Synonyms:
FAS, Fas, fas
Insert length:
984 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pCMV6-AC
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to FAS

  • Fas cell surface death receptor (FAS)
  • Fas (TNF receptor superfamily member 6) (Fas)
  • Fas cell surface death receptor (Fas)
  • Fas cell surface death receptor (fas)
  • AI196731
  • ALPS1A
  • APO-1
  • APO1
  • APT1
  • CD95
  • FAS1
  • FASTM
  • lpr
  • TNFR6
  • TNFRSF6
  • Tnfrsf6

Gene-IDs for different species

Protein level used designations for FAS

  • APO-1 cell surface antigen
  • CD95 antigen
  • Delta Fas/APO-1/CD95
  • FAS 827dupA
  • FASLG receptor
  • Fas (TNF receptor superfamily, member 6)
  • Fas AMA
  • TNF receptor superfamily member 6
  • apoptosis antigen 1
  • apoptosis-mediating surface antigen FAS
  • tumor necrosis factor receptor superfamily member 6
  • tumor necrosis factor receptor superfamily, member 6
  • Fas antigen
  • Fas (TNF receptor superfamily member)
  • apo-1 antigen
  • lymphoproliferation
  • Fas antigen (ATP1)
  • Fas receptor
  • Tumor necrosis factor receptor superfamily, member 6
  • apoptosis (APO-1) antigen 1 ( FAS ), member 6
  • Fas receptor CD95
Other products related to FAS such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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