FBXW7 (F-Box and WD Repeat Domain Containing 7, FBXW7)
Short Description: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class\; in addition to an F-box, this protein contains 7 tandem WD40 repeats. This protein binds directly to cyclin E and probably targets cyclin E for ubiquitin-mediated degradation. Mutations in this gene are detected in ovarian and breast cancer cell lines, implicating the gene's potential role in the pathogenesis of human cancers. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012].
More information related to gene FBXW7.
More information related to gene FBXW7.
Products related to FBXW7 Gene:
Recommended next Filters:
67 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- F-Box and WD Repeat Domain Containing 7 (FBXW7)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- F-Box and WD Repeat Domain Containing 7 (FBXW7)
- NCBI Accession:
- NM_001177773
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- F-Box and WD Repeat Domain Containing 7 (FBXW7)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- F-Box and WD Repeat Domain Containing 7 (FBXW7)
- NCBI Accession:
- NM_001177773
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- F-Box and WD Repeat Domain Containing 7 (FBXW7)
- NCBI Accession:
- NM_001177773
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- F-Box and WD Repeat Domain Containing 7 (FBXW7)
- NCBI Accession:
- NM_018315
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- F-Box and WD Repeat Domain Containing 7 (FBXW7)
- NCBI Accession:
- NM_001177773
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- F-Box and WD Repeat Domain Containing 7 (FBXW7)
- NCBI Accession:
- NM_018315
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- F-Box and WD Repeat Domain Containing 7 (FBXW7)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- F-Box and WD Repeat Domain Containing 7 (FBXW7)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
Synonyms and alternative names related to FBXW7
- F-box and WD repeat domain containing 7 (Fbxw7)
- F-box and WD repeat domain containing 7 (FBXW7)
- F-box and WD repeat domain containing 7 (fbxw7)
- F-box and WD-40 domain protein 7 (Fbxw7)
- 1110001A17Rik
- AGO
- cdc4
- CDC4
- Cdc4
- FBW6
- FBW7
- Fbw7
- Fbwd6
- FBX30
- Fbx30
- FBXO30
- Fbxo30
- FBXW6
- Fbxw6
- hAgo
- hCdc4
- SEL-10
- SEL10
Gene-IDs for different species
Protein level used designations for FBXW7
- F-box and WD-40 domain protein 7
- F-box/WD repeat-containing protein 7
- F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila)
- F-box protein FBW7
- F-box protein FBX30
- F-box protein SEL-10
- archipelago
- homolog of C elegans sel-10
- F-box and WD-40 domain protein 7, archipelago homolog
- F-box and WD-40 domain-containing protein 7
- F-box protein Fbxw6
- F-box-WD40 repeat protein 6
- f-box only protein 30
Proteomics products related to FBXW7 Gene
Other products related to FBXW7 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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