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FGFR1 (Fibroblast Growth Factor Receptor 1, FGFR1)

Short Description: The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described\; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].
More information related to gene FGFR1.

Products related to FGFR1 Gene:

116 results :

cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Fibroblast Growth Factor Receptor 1 (FGFR1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4831577
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Fibroblast Growth Factor Receptor 1 (FGFR1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4702447
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Fibroblast Growth Factor Receptor 1 (FGFR1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4475654
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fibroblast Growth Factor Receptor 1 (FGFR1)
NCBI Accession:
NM_010206
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5081314
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fibroblast Growth Factor Receptor 1 (FGFR1)
NCBI Accession:
NM_024146
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5081316
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fibroblast Growth Factor Receptor 1 (FGFR1)
NCBI Accession:
NM_015850
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5081312
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Fibroblast Growth Factor Receptor 1 (FGFR1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4762029
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Fibroblast Growth Factor Receptor 1 (FGFR1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4831576
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Fibroblast Growth Factor Receptor 1 (FGFR1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4702446
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Fibroblast Growth Factor Receptor 1 (FGFR1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4436749
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • His-GST
    • His-MBP
    • HA tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pcDNA3.1+C-(K)-DYK
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-XL4
    • pCMV6-XL5
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCas-Guide
    • pRFP-C-RS
    • pCMV6-AC
    • pCMV6-Neo
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • T7 Promoter
    • U6 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to FGFR1

  • fibroblast growth factor receptor (FGFR)
  • fibroblast growth factor receptor (fgfr)
  • fibroblast growth factor receptor 1 S homeolog (fgfr1.S)
  • basic fibroblast growth factor receptor 1 (CpipJ_CPIJ005849)
  • heartless (htl)
  • fibroblast growth factor receptor 1 (fgfr1)
  • fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog (fgfr3.L)
  • fibroblast growth factor receptor 1 (FGFR1)
  • fibroblast growth factor receptor 1 (Fgfr1)
  • Fibroblast growth factor receptor 1 (Fgfr1)
  • fibroblast growth factor receptor 1 L homeolog (fgfr1.L)
  • fibroblast growth factor receptor 1a (fgfr1a)
  • ach
  • AW208770
  • bFGF-R-1
  • bfgfr
  • BFGFR
  • cb231
  • cd331
  • CD331
  • cd333
  • cek
  • CEK
  • cek2
  • CG7223
  • CT22273
  • CT39172
  • DFGF-R1
  • DFGF-R2
  • DFR-1
  • Dfr-1
  • DFR1
  • Dfr1
  • DFR1/DFGF-R2
  • Dmel\\CG7223
  • DmHD-38
  • DPR3
  • Dtk1
  • dtk1
  • DTRK(FR1)
  • Eask
  • EMS2
  • FGF-R2
  • fgfbr
  • FGFBR
  • FGFR
  • fgfr
  • fgfr-1
  • FGFR-1
  • Fgfr-1
  • fgfr-3
  • fgfr1
  • FGFR2
  • FGFRI
  • flg
  • FLG
  • FLG-1
  • flt-2
  • FLT-2
  • Flt-2
  • flt2
  • FLT2
  • FR1
  • Fr1
  • hbgfr
  • HBGFR
  • HD-38
  • HH2
  • hsfgfr3ex
  • Hspy
  • Htl
  • HTL/FGFR1
  • i79
  • i100
  • i150
  • j372
  • jtk4
  • kal2
  • KAL2
  • n-sam
  • N-SAM
  • ogd
  • OGD
  • sb:cb231
  • Tk1
  • X1FGFR
  • x1fgfr
  • XFGFR-1
  • xfgfr1
  • XFGFRA2

Gene-IDs for different species

Protein level used designations for FGFR1

  • fibroblast growth factor receptor
  • FGFR-1
  • fibroblast growth factor receptor-1
  • basic fibroblast growth factor receptor 1
  • CG7223-PA
  • CG7223-PB
  • CG7223-PC
  • FGF receptor
  • fibroblast growth factor receptor 1
  • htl-PA
  • htl-PB
  • htl-PC
  • fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
  • ibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
  • basic fibroblast growth factor receptor 1-like
  • FGFR1/PLAG1 fusion
  • FMS-like tyrosine kinase 2
  • fms-related tyrosine kinase 2
  • heparin-binding growth factor receptor
  • hydroxyaryl-protein kinase
  • proto-oncogene c-Fgr
  • MFR
  • bFGF-R-1
  • c-fgr
  • FGF receptor-1
  • bFGF-R
  • cek1 protein
  • tyrosine kinase receptor CEK1
  • FGFR-1-A
  • bFGF-R-1-A
  • basic fibroblast growth factor receptor 1-A
  • fibroblast growth factor receptor 1-A
Other products related to FGFR1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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