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FZR1 (Fizzy/cell Division Cycle 20 Related 1, FZR1)

Short Description: Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA damage, it is required for the G2 DNA damage leads to the ubiquitination of PLK1, preventing entry into mitosis (By similarity).
More information related to gene FZR1.

Products related to FZR1 Gene:

63 results :

Human FZR1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5740668
Datasheet
Catalog No. ABIN5740668
Type:
ORF
Application:
Cloning
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
Species:
Human
Synonyms:
Fzr1, CDH1-C, FZR1, LOC100027495, LOC100179951, fzr1a
Insert length:
1482 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human FZR1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4475854
Datasheet
Catalog No. ABIN4475854
Type:
cDNA
Application:
Protein Expression
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
Species:
Human
Synonyms:
Fzr1, CDH1-C, FZR1, LOC100027495, LOC100179951, fzr1a
Insert length:
1482 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat FZR1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
NCBI Accession:
NM_001108074
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5234458
Datasheet
Catalog No. ABIN5234458
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
NCBI Accession:
NM_001108074
Species:
Rat
Synonyms:
Fzr1, CDH1-C, FZR1, LOC100027495, LOC100179951, fzr1a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Fzr1
Format:
Viral Particles
Storage:
-80 °C
Mouse FZR1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
NCBI Accession:
NM_019757
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5234456
Datasheet
Catalog No. ABIN5234456
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
NCBI Accession:
NM_019757
Species:
Mouse
Synonyms:
Fzr1, CDH1-C, FZR1, LOC100027495, LOC100179951, fzr1a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Fzr1
Format:
Viral Particles
Storage:
-80 °C
Human FZR1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
NCBI Accession:
NM_016263
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5234454
Datasheet
Catalog No. ABIN5234454
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
NCBI Accession:
NM_016263
Species:
Human
Synonyms:
Fzr1, CDH1-C, FZR1, LOC100027495, LOC100179951, fzr1a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of FZR1
Format:
Viral Particles
Storage:
-80 °C
Rat FZR1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
NCBI Accession:
NM_001108074
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5119100
Datasheet
Catalog No. ABIN5119100
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
NCBI Accession:
NM_001108074
Species:
Rat
Synonyms:
Fzr1, CDH1-C, FZR1, LOC100027495, LOC100179951, fzr1a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Fzr1
Format:
Viral Particles
Storage:
-80 °C
Mouse FZR1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
NCBI Accession:
NM_019757
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5119098
Datasheet
Catalog No. ABIN5119098
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
NCBI Accession:
NM_019757
Species:
Mouse
Synonyms:
Fzr1, CDH1-C, FZR1, LOC100027495, LOC100179951, fzr1a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Fzr1
Format:
Viral Particles
Storage:
-80 °C
Human FZR1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
NCBI Accession:
NM_016263
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5119096
Datasheet
Catalog No. ABIN5119096
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
NCBI Accession:
NM_016263
Species:
Human
Synonyms:
Fzr1, CDH1-C, FZR1, LOC100027495, LOC100179951, fzr1a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of FZR1
Format:
Viral Particles
Storage:
-80 °C
Human FZR1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4831855
Datasheet
Catalog No. ABIN4831855
Type:
cDNA
Application:
Cloning
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
Species:
Human
Synonyms:
Fzr1, CDH1-C, FZR1, LOC100027495, LOC100179951, fzr1a
Insert length:
1482 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human FZR1 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4762229
Datasheet
Catalog No. ABIN4762229
Type:
cDNA
Application:
Cloning
Gene:
Fizzy/cell Division Cycle 20 Related 1 (Drosophila) (FZR1)
Species:
Human
Synonyms:
Fzr1, CDH1-C, FZR1, LOC100027495, LOC100179951, fzr1a
Insert length:
1482 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to FZR1

  • fizzy and cell division cycle 20 related 1 (Fzr1)
  • fizzy/cell division cycle 20 related 1 (CDH1-C)
  • fizzy and cell division cycle 20 related 1 (FZR1)
  • fizzy-related protein homolog (LOC100027495)
  • fizzy-related protein homolog (LOC100179951)
  • fizzy/cell division cycle 20 related 1 (Drosophila) (Fzr1)
  • fizzy/cell division cycle 20 related 1a (fzr1a)
  • AW108046
  • CDC20C
  • CDH1
  • Cdh1
  • CDH1-C
  • FYR
  • Fyr
  • FZR
  • fzr1
  • FZR2
  • HCDH
  • HCDH1
  • zgc:55450

Gene-IDs for different species

Protein level used designations for FZR1

  • fizzy-related protein homolog
  • fizzy/cell division cycle 20 related 1 (Drosophila)
  • fizzy-related protein FZR
  • Fizzy-related protein-like protein
  • fizzy/cell division cycle 20 related 1
  • CDC20-like 1b
  • CDC20-like protein 1
  • cdh1/Hct1 homolog
  • cell division cycle 20 related 1
Other products related to FZR1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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