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GALE (UDP-Galactose-4-Epimerase, GALE)

Short Description: This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Jul 2008].
More information related to gene GALE.

Products related to GALE Gene:

63 results :

Human GALE ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
UDP-Galactose-4-Epimerase (GALE)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5755355
Datasheet
Catalog No. ABIN5755355
Type:
ORF
Application:
Cloning
Gene:
UDP-Galactose-4-Epimerase (GALE)
Species:
Human
Synonyms:
GALE, gale, RHD1, ECs0787, galE, galE1, galE2, STY0809, galE-2, SG0897, galD, Ent638_1250, Gale, gale.L
Insert length:
1047 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human GALE cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
UDP-Galactose-4-Epimerase (GALE)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4475892
Datasheet
Catalog No. ABIN4475892
Type:
cDNA
Application:
Protein Expression
Gene:
UDP-Galactose-4-Epimerase (GALE)
Species:
Human
Synonyms:
GALE, gale, RHD1, ECs0787, galE, galE1, galE2, STY0809, galE-2, SG0897, galD, Ent638_1250, Gale, gale.L
Insert length:
1047 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat GALE CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
UDP-Galactose-4-Epimerase (GALE)
NCBI Accession:
NM_080783
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5263341
Datasheet
Catalog No. ABIN5263341
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
UDP-Galactose-4-Epimerase (GALE)
NCBI Accession:
NM_080783
Species:
Rat
Synonyms:
GALE, gale, RHD1, ECs0787, galE, galE1, galE2, STY0809, galE-2, SG0897, galD, Ent638_1250, Gale, gale.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Gale
Format:
Viral Particles
Storage:
-80 °C
Mouse GALE CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
UDP-Galactose-4-Epimerase (GALE)
NCBI Accession:
NM_178389
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5263339
Datasheet
Catalog No. ABIN5263339
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
UDP-Galactose-4-Epimerase (GALE)
NCBI Accession:
NM_178389
Species:
Mouse
Synonyms:
GALE, gale, RHD1, ECs0787, galE, galE1, galE2, STY0809, galE-2, SG0897, galD, Ent638_1250, Gale, gale.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Gale
Format:
Viral Particles
Storage:
-80 °C
Human GALE CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
UDP-Galactose-4-Epimerase (GALE)
NCBI Accession:
NM_000403
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5263337
Datasheet
Catalog No. ABIN5263337
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
UDP-Galactose-4-Epimerase (GALE)
NCBI Accession:
NM_000403
Species:
Human
Synonyms:
GALE, gale, RHD1, ECs0787, galE, galE1, galE2, STY0809, galE-2, SG0897, galD, Ent638_1250, Gale, gale.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of GALE
Format:
Viral Particles
Storage:
-80 °C
Rat GALE CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
UDP-Galactose-4-Epimerase (GALE)
NCBI Accession:
NM_080783
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5147810
Datasheet
Catalog No. ABIN5147810
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
UDP-Galactose-4-Epimerase (GALE)
NCBI Accession:
NM_080783
Species:
Rat
Synonyms:
GALE, gale, RHD1, ECs0787, galE, galE1, galE2, STY0809, galE-2, SG0897, galD, Ent638_1250, Gale, gale.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Gale
Format:
Viral Particles
Storage:
-80 °C
Mouse GALE CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
UDP-Galactose-4-Epimerase (GALE)
NCBI Accession:
NM_178389
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5147808
Datasheet
Catalog No. ABIN5147808
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
UDP-Galactose-4-Epimerase (GALE)
NCBI Accession:
NM_178389
Species:
Mouse
Synonyms:
GALE, gale, RHD1, ECs0787, galE, galE1, galE2, STY0809, galE-2, SG0897, galD, Ent638_1250, Gale, gale.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Gale
Format:
Viral Particles
Storage:
-80 °C
Human GALE CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
UDP-Galactose-4-Epimerase (GALE)
NCBI Accession:
NM_000403
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5147806
Datasheet
Catalog No. ABIN5147806
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
UDP-Galactose-4-Epimerase (GALE)
NCBI Accession:
NM_000403
Species:
Human
Synonyms:
GALE, gale, RHD1, ECs0787, galE, galE1, galE2, STY0809, galE-2, SG0897, galD, Ent638_1250, Gale, gale.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of GALE
Format:
Viral Particles
Storage:
-80 °C
Human GALE cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
UDP-Galactose-4-Epimerase (GALE)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4831920
Datasheet
Catalog No. ABIN4831920
Type:
cDNA
Application:
Cloning
Gene:
UDP-Galactose-4-Epimerase (GALE)
Species:
Human
Synonyms:
GALE, gale, RHD1, ECs0787, galE, galE1, galE2, STY0809, galE-2, SG0897, galD, Ent638_1250, Gale, gale.L
Insert length:
1047 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human GALE cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
UDP-Galactose-4-Epimerase (GALE)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4762267
Datasheet
Catalog No. ABIN4762267
Type:
cDNA
Application:
Cloning
Gene:
UDP-Galactose-4-Epimerase (GALE)
Species:
Human
Synonyms:
GALE, gale, RHD1, ECs0787, galE, galE1, galE2, STY0809, galE-2, SG0897, galD, Ent638_1250, Gale, gale.L
Insert length:
1047 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC
    • pCMV6-XL4
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to GALE

  • UDP-galactose-4-epimerase (GALE)
  • UDP-galactose-4-epimerase (gale)
  • NAD(P)-binding Rossmann-fold superfamily protein (RHD1)
  • UDP-galactose-4-epimerase (ECs0787)
  • UDP-galactose-4-epimerase (galE)
  • UDP-galactose 4-epimerase GalE (galE)
  • UDP-glucose 4-epimerase (galE1)
  • UDP-glucose 4-epimerase (galE2)
  • UDP-glucose 4-epimerase GalE (galE)
  • UDP-glucose 4-epimerase (STY0809)
  • UDP-glucose 4-epimerase (galE)
  • UDP-glucose/UDP-N-acetylglucosamine 4-epimerase (galE)
  • UDP-glucose 4-epimerase (galE-2)
  • UDP-galactose-4-epimerase (SG0897)
  • UDP-galactose-4-epimerase (galD)
  • UDP-galactose-4-epimerase (Ent638_1250)
  • galactose-4-epimerase, UDP (Gale)
  • UDP-galactose-4-epimerase L homeolog (gale.L)
  • UDP-galactose-4-epimerase (Gale)
  • 1n569
  • 2310002A12Rik
  • AI323962
  • BA5505
  • BA5700
  • ECK0748
  • F15H21.11
  • F15H21_11
  • galD
  • GALE
  • galE
  • im:7147391
  • JW0742
  • REB1
  • ROOT EPIDERMAL BULGER1
  • ROOT HAIR DEFECTIVE 1
  • SDR1E1
  • SMU.888
  • UDP-GLUCOSE 4-EPIMERASE
  • UGE4
  • VFA0352
  • wu:fb05f01
  • xgale
  • zgc:136578

Gene-IDs for different species

Protein level used designations for GALE

  • UDP-galactose-4-epimerase
  • UDP-glucose 4-epimerase
  • fb05f01
  • UDP-galactose 4-epimerase
  • galactowaldenase
  • UDP-glucose (37.7 kD) (1N569)
  • UDP galactose-4'-epimerase
  • galactose-4-epimerase, UDP-
  • short chain dehydrogenase/reductase family 1E, member 1
  • galactose-4-epimerase, UDP
Other products related to GALE such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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