Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@genomics-online.com

GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit, GCLC)

Short Description: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010].
More information related to gene GCLC.

Products related to GCLC Gene:

66 results :

Human GCLC ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5740968
Datasheet
Catalog No. ABIN5740968
Type:
ORF
Application:
Cloning
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
Species:
Human
Synonyms:
GCLC, gclc, Gclc, LbGCS, gcsA, gclc.L, gclc.S, GSH1
Insert length:
759 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human GCLC ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5740969
Datasheet
Catalog No. ABIN5740969
Type:
ORF
Application:
Cloning
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
Species:
Human
Synonyms:
GCLC, gclc, Gclc, LbGCS, gcsA, gclc.L, gclc.S, GSH1
Insert length:
1914 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse GCLC ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
NCBI Accession:
NM_010295
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5740970
Datasheet
Catalog No. ABIN5740970
Type:
ORF
Application:
Cloning
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
NCBI Accession:
NM_010295
Species:
Mouse
Synonyms:
GCLC, gclc, Gclc, LbGCS, gcsA, gclc.L, gclc.S, GSH1
Insert length:
1914 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human GCLC cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4475953
Datasheet
Catalog No. ABIN4475953
Type:
cDNA
Application:
Protein Expression
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
Species:
Human
Synonyms:
GCLC, gclc, Gclc, LbGCS, gcsA, gclc.L, gclc.S, GSH1
Insert length:
759 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human GCLC cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4475954
Datasheet
Catalog No. ABIN4475954
Type:
cDNA
Application:
Protein Expression
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
Species:
Human
Synonyms:
GCLC, gclc, Gclc, LbGCS, gcsA, gclc.L, gclc.S, GSH1
Insert length:
759 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse GCLC cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
NCBI Accession:
NM_010295
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4444181
Datasheet
Catalog No. ABIN4444181
Type:
cDNA
Application:
Protein Expression
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
NCBI Accession:
NM_010295
Species:
Mouse
Synonyms:
GCLC, gclc, Gclc, LbGCS, gcsA, gclc.L, gclc.S, GSH1
Insert length:
1914 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat GCLC CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
NCBI Accession:
NM_012815
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5235004
Datasheet
Catalog No. ABIN5235004
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
NCBI Accession:
NM_012815
Species:
Rat
Synonyms:
GCLC, gclc, Gclc, LbGCS, gcsA, gclc.L, gclc.S, GSH1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Gclc
Format:
Viral Particles
Storage:
-80 °C
Mouse GCLC CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
NCBI Accession:
NM_010295
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5235002
Datasheet
Catalog No. ABIN5235002
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
NCBI Accession:
NM_010295
Species:
Mouse
Synonyms:
GCLC, gclc, Gclc, LbGCS, gcsA, gclc.L, gclc.S, GSH1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Gclc
Format:
Viral Particles
Storage:
-80 °C
Human GCLC CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
NCBI Accession:
NM_001498
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5235000
Datasheet
Catalog No. ABIN5235000
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
NCBI Accession:
NM_001498
Species:
Human
Synonyms:
GCLC, gclc, Gclc, LbGCS, gcsA, gclc.L, gclc.S, GSH1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of GCLC
Format:
Viral Particles
Storage:
-80 °C
Rat GCLC CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
NCBI Accession:
NM_012815
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5119644
Datasheet
Catalog No. ABIN5119644
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC)
NCBI Accession:
NM_012815
Species:
Rat
Synonyms:
GCLC, gclc, Gclc, LbGCS, gcsA, gclc.L, gclc.S, GSH1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Gclc
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pDONR223
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL4
    • pRFP-C-RS
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to GCLC

  • glutamate-cysteine ligase catalytic subunit (GCLC)
  • glutamate-cysteine ligase, catalytic subunit (gclc)
  • Glutamate-cysteine ligase catalytic subunit (Gclc)
  • gamma glutamylcysteine synthetase (LbGCS)
  • gamma glutamylcysteine synthetase (gcsA)
  • glutamate-cysteine ligase, catalytic subunit L homeolog (gclc.L)
  • glutamate-cysteine ligase, catalytic subunit S homeolog (gclc.S)
  • gamma-glutamylcysteine synthetase (GSH1)
  • glutamate-cysteine ligase, catalytic subunit (Gclc)
  • glutamate-cysteine ligase catalytic subunit (Gclc)
  • 2259
  • cb1049
  • CG2259
  • D9Wsu168e
  • DDBDRAFT_0186120
  • DDBDRAFT_0231403
  • DDB_0186120
  • DDB_0231403
  • Dmel\\CG2259
  • DmGCLC
  • DmGCS
  • DmGCSh
  • fe36e11
  • GCL
  • GCLC
  • gclc
  • GCLc
  • Gcs
  • GCS
  • GCSh
  • Gcsh
  • Ggcs-hs
  • GLCL
  • GLCL-H
  • GLCLC
  • Glclc
  • MGC146287
  • wu:fe36e11

Gene-IDs for different species

Protein level used designations for GCLC

  • glutamate--cysteine ligase catalytic subunit
  • glutamate-cysteine ligase, catalytic subunit
  • CG2259-PA
  • CG2259-PB
  • Gclc-PA
  • Gclc-PB
  • gamma-Glutamylcysteine synthetase
  • gamma-Glutamylcysteine synthetase catalytic subunit
  • gamma-glutamylcysteine ligase
  • glutamate cysteine ligase
  • glutamate-cysteine ligase
  • gamma glutamylcysteine synthetase
  • gamma-ECS
  • glutamate--cysteine ligase, chloroplastic
  • GCS heavy chain
  • gamma-glutamylcysteine synthetase
  • gamma GCS-HS
  • gamma-glutamylcysteine synthetase heavy subunit
  • Glutamylcysteine gamma synthetase light chain
  • glutamate-cysteine ligase catalytic subunit
Other products related to GCLC such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
You are here:

antibodies-online

german

german (deutsch) antikoerper-online.de

english

english (english) antibodies-online.com

french

french (français) anticorps-enligne.fr

chinese

chinese (中文) antibodies-online.cn

genomics-online

english

english (english) genomics-online.com

Support