Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@genomics-online.com

GNAS (GNAS Complex Locus, GNAS)

Short Description: This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors. [provided by RefSeq, Aug 2012].
More information related to gene GNAS.

Products related to GNAS Gene:

118 results :

ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
GNAS Complex Locus (GNAS)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5724179
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
GNAS Complex Locus (GNAS)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5724180
cDNA PExp Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Protein Expression
Gene:
GNAS Complex Locus (GNAS)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN5772226
cDNA PExp Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Protein Expression
Gene:
GNAS Complex Locus (GNAS)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN5772227
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
GNAS Complex Locus (GNAS)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4476106
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
GNAS Complex Locus (GNAS)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4476107
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
GNAS Complex Locus (GNAS)
NCBI Accession:
NM_001159653
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5089532
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
GNAS Complex Locus (GNAS)
NCBI Accession:
NM_001077510
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5089530
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
GNAS Complex Locus (GNAS)
NCBI Accession:
NM_000516
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5089528
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
GNAS Complex Locus (GNAS)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4762482
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • Myc-DYKDDDDK Tag
    • GFP tag
    • His tag
    • DYKDDDDK Tag
    • His-GST
    • His-MBP
    • HA tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pcDNA3.1+C-(K)-DYK
    • pPB-His-GST
    • pPB-His-MBP
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-XL5
    • pCas-Guide
    • pDONR223
    • pCMV6-XL4
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to GNAS

  • GNAS complex locus (GNAS)
  • guanine nucleotide-binding protein G(s) subunit alpha (LOC694289)
  • guanine nucleotide-binding protein G(s) subunit alpha (LOC469986)
  • GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus (Gnas)
  • GNAS complex locus S homeolog (gnas.S)
  • GNAS complex locus (Gnas)
  • GNAS complex locus (gnas)
  • neuroendocrine secretory protein 55-like (LOC100346323)
  • guanine nucleotide-binding protein G(s) subunit alpha (LOC100442753)
  • guanine nucleotide-binding protein G(s) subunit alpha (LOC100732436)
  • 5530400H20Rik
  • A930027G11Rik
  • AHO
  • C20orf45
  • C130027O20Rik
  • G-alpha-S
  • G-alpha-s
  • Galphas
  • gnal
  • GNAS
  • Gnas
  • gnas-a
  • GNAS1
  • Gnas1
  • Gnasxl
  • Gnpas
  • GPSA
  • GSA
  • Gsa
  • GSP
  • NESP
  • Nesp
  • Nesp55
  • Nespl
  • Oed-Sml
  • Oedsml
  • P1
  • P2
  • P3
  • PHP1A
  • PHP1B
  • PHP1C
  • POH
  • PORGSA1

Gene-IDs for different species

Protein level used designations for GNAS

  • adenylate cyclase-stimulating G alpha protein
  • alternative gene product encoded by XL-exon
  • extra large alphas protein
  • guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1
  • guanine nucleotide regulatory protein
  • guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas
  • neuroendocrine secretory protein
  • protein ALEX
  • secretogranin VI
  • GNAS complex locus
  • GTP-binding regulatory protein alpha subunit exon 1
  • guanine nucleotide binding protein, alpha stimulating activity polypeptide 1
  • guanine nucleotide-binding protein G(s) subunit alpha
  • stimulatory GTP binding protein
  • alpha-stimulatory subunit of GTP-binding protein
  • guanine nucleotide-binding protein, alpha-stimulating activity polypeptide 1
  • Gs alpha subunit
  • neuroendocrine secretory protein 55
  • stimulatory G-protein alpha subunit
  • guanine nucleotide-binding protein G(s) subunit alpha isoforms
  • G-alpha-8
  • GNAS
  • GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
  • guanine nucleotide binding protein alpha s
  • guanine nucleotide-binding protein G-s, alpha subunit
  • guanine nucleotide binding protein, alpha stimulating, olfactory type
  • guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas-like
  • Galpha s
Other products related to GNAS such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
You are here:
Support