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HECW1 (HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1, HECW1)

Short Description: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.
More information related to gene HECW1.

Products related to HECW1 Gene:

57 results :

Rat HECW1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_001106117
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5288757
Datasheet
Catalog No. ABIN5288757
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_001106117
Species:
Rat
Synonyms:
HECW1, Hecw1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Hecw1
Format:
Viral Particles
Storage:
-80 °C
Mouse HECW1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_001081348
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5288755
Datasheet
Catalog No. ABIN5288755
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_001081348
Species:
Mouse
Synonyms:
HECW1, Hecw1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Hecw1
Format:
Viral Particles
Storage:
-80 °C
Human HECW1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_015052
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5288753
Datasheet
Catalog No. ABIN5288753
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_015052
Species:
Human
Synonyms:
HECW1, Hecw1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of HECW1
Format:
Viral Particles
Storage:
-80 °C
Rat HECW1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_001106117
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5173162
Datasheet
Catalog No. ABIN5173162
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_001106117
Species:
Rat
Synonyms:
HECW1, Hecw1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Hecw1
Format:
Viral Particles
Storage:
-80 °C
Mouse HECW1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_001081348
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5173160
Datasheet
Catalog No. ABIN5173160
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_001081348
Species:
Mouse
Synonyms:
HECW1, Hecw1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Hecw1
Format:
Viral Particles
Storage:
-80 °C
Human HECW1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_015052
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5173158
Datasheet
Catalog No. ABIN5173158
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_015052
Species:
Human
Synonyms:
HECW1, Hecw1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of HECW1
Format:
Viral Particles
Storage:
-80 °C
Human HECW1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_015052
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5768029
Datasheet
Catalog No. ABIN5768029
Type:
ORF
Application:
Cloning
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_015052
Species:
Human
Synonyms:
HECW1, Hecw1
Insert length:
4821 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat HECW1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_001106117
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5288756
Datasheet
Catalog No. ABIN5288756
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_001106117
Species:
Rat
Synonyms:
HECW1, Hecw1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Hecw1
Format:
Viral Particles
Storage:
-80 °C
Mouse HECW1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_001081348
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5288754
Datasheet
Catalog No. ABIN5288754
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_001081348
Species:
Mouse
Synonyms:
HECW1, Hecw1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Hecw1
Format:
Viral Particles
Storage:
-80 °C
Human HECW1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_015052
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5288752
Datasheet
Catalog No. ABIN5288752
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
HECT, C2 and WW Domain Containing E3 Ubiquitin Protein Ligase 1 (HECW1)
NCBI Accession:
NM_015052
Species:
Human
Synonyms:
HECW1, Hecw1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of HECW1
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC-GFP
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • shRNA
    • ORF
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to HECW1

  • HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 (HECW1)
  • HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 (Hecw1)
  • 9330116H24Rik
  • AV273951
  • E130207I19Rik
  • NEDL1
  • Nedl1

Gene-IDs for different species

Protein level used designations for HECW1

  • E3 ubiquitin-protein ligase HECW1
  • HECT type E3 ubiquitin ligase
  • HECT, C2 and WW domain-containing protein 1
  • NEDD4-like E3 ubiquitin-protein ligase 1
  • NEDD4-like ubiquitin-protein ligase 1
  • mNEDL1
Other products related to HECW1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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