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HLA-B (Major Histocompatibility Complex, Class I, B, HLA-B)

Short Description: HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. [provided by RefSeq, Jul 2008].
More information related to gene HLA-B.

Products related to HLA-B Gene:

18 results :

Human HLA-B ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5726600
Datasheet
Catalog No. ABIN5726600
Type:
ORF
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
Species:
Human
Synonyms:
HLA-B, BOLA-B, MAMU-B18, DKFZP469N1225, mhc1b.L
Insert length:
1089 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human HLA-B cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4832942
Datasheet
Catalog No. ABIN4832942
Type:
cDNA
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
Species:
Human
Synonyms:
HLA-B, BOLA-B, MAMU-B18, DKFZP469N1225, mhc1b.L
Insert length:
1101 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human HLA-B cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4703812
Datasheet
Catalog No. ABIN4703812
Type:
cDNA
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
Species:
Human
Synonyms:
HLA-B, BOLA-B, MAMU-B18, DKFZP469N1225, mhc1b.L
Insert length:
1101 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human HLA-B cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4476556
Datasheet
Catalog No. ABIN4476556
Type:
cDNA
Application:
Protein Expression
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
Species:
Human
Synonyms:
HLA-B, BOLA-B, MAMU-B18, DKFZP469N1225, mhc1b.L
Insert length:
1089 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human HLA-B CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
NCBI Accession:
NM_005514
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5092788
Datasheet
Catalog No. ABIN5092788
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
NCBI Accession:
NM_005514
Species:
Human
Synonyms:
HLA-B, BOLA-B, MAMU-B18, DKFZP469N1225, mhc1b.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of HLA-B
Format:
Viral Particles
Storage:
-80 °C
Human HLA-B cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4832943
Datasheet
Catalog No. ABIN4832943
Type:
cDNA
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
Species:
Human
Synonyms:
HLA-B, BOLA-B, MAMU-B18, DKFZP469N1225, mhc1b.L
Insert length:
1089 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human HLA-B cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4762931
Datasheet
Catalog No. ABIN4762931
Type:
cDNA
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
Species:
Human
Synonyms:
HLA-B, BOLA-B, MAMU-B18, DKFZP469N1225, mhc1b.L
Insert length:
1089 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human HLA-B cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4703813
Datasheet
Catalog No. ABIN4703813
Type:
cDNA
Application:
Cloning
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
Species:
Human
Synonyms:
HLA-B, BOLA-B, MAMU-B18, DKFZP469N1225, mhc1b.L
Insert length:
1089 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human HLA-B cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4437651
Datasheet
Catalog No. ABIN4437651
Type:
cDNA
Application:
Protein Expression
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
Species:
Human
Synonyms:
HLA-B, BOLA-B, MAMU-B18, DKFZP469N1225, mhc1b.L
Insert length:
1089 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human HLA-B CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
NCBI Accession:
NM_005514
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5207976
Datasheet
Catalog No. ABIN5207976
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Major Histocompatibility Complex, Class I, B (HLA-B)
NCBI Accession:
NM_005514
Species:
Human
Synonyms:
HLA-B, BOLA-B, MAMU-B18, DKFZP469N1225, mhc1b.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of HLA-B
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • His-GST
    • His-MBP
    • Myc-DYKDDDDK Tag
    • DYKDDDDK Tag
    • HA tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pPB-His-GST
    • pPB-His-MBP
    • pCMV6-AC-GFP
    • pCMV6-Entry
    • pDONR223
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Mammalian Expression Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • gRNA
    • gRNA + Cas9
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • T7 Promoter
    • U6 Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Liquid
    • Lyophilized
    • Viral Particles

Synonyms and alternative names related to HLA-B

  • major histocompatibility complex, class I, B (HLA-B)
  • major histocompatibility complex, class I, B (BOLA-B)
  • major histocompatibility complex, class I, B (MAMU-B18)
  • major histocompatibility complex, class I, B (DKFZP469N1225)
  • major histocompatibility complex nonclassical class Ib L homeolog (mhc1b.L)
  • AS
  • HLAB
  • mhc1b
  • SPDA1

Gene-IDs for different species

Protein level used designations for HLA-B

  • HLA class I histocompatibility antigen, B alpha chain
  • MHC Class I HLA heavy chain
  • MHC HLA-B cell surface glycoprotein
  • MHC HLA-B transmembrane glycoprotein
  • MHC class I antigen GN00104
  • MHC class I antigen HLA-B heavy chain
  • MHC class I antigen SHCHA
  • leukocyte antigen class I-B
  • lymphocyte antigen
  • major histocompatibility complex, class I, B
  • major histocompatibility complex nonclassical class Ib L homeolog
Other products related to HLA-B such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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