HLA-DQA1 (Major Histocompatibility Complex, Class II, DQ alpha 1, HLA-DQA1)
Short Description: HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons\; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq, Jul 2008].
More information related to gene HLA-DQA1.
More information related to gene HLA-DQA1.
Products related to HLA-DQA1 Gene:
Recommended next Filters:
30 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1)
- NCBI Accession:
- NM_002122
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1)
- NCBI Accession:
- NM_002122
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-His
Kanamycin
CMV Promoter
His tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-His
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- His tag
- Expression:
- Stable, Transient
Synonyms and alternative names related to HLA-DQA1
- major histocompatibility complex, class II, DQ alpha 1 (HLA-DQA1)
- major histocompatibility complex, class II, DQ alpha, type 1 (BOLA-DQA1)
- major histocompatibility complex, class II, DQ alpha 1 L homeolog (hla-dqa1.L)
- BoLA-DQA
- CD
- CELIAC1
- DQ-A1
- GSE
- HLA-DQA
- hla-dqa1
Gene-IDs for different species
Protein level used designations for HLA-DQA1
- DC-1 alpha chain
- DC-alpha
- HLA class II histocompatibility antigen, DQ alpha 1 chain
- HLA class II histocompatibility antigen, DQ(W3) alpha chain
- HLA-DCA
- MHC HLA-DQ alpha
- MHC class II DQA1
- MHC class II HLA-D alpha glycoprotein
- MHC class II HLA-DQ-alpha-1
- MHC class II antigen
- MHC class II surface glycoprotein
- leucocyte antigen DQA1
- leukocyte antigen alpha chain
- major histocompatibility complex, class II, DQ alpha, type 1
- major histocompatibility complex, class II, DQ alpha 1 L homeolog
Proteomics products related to HLA-DQA1 Gene
Other products related to HLA-DQA1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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