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HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial), HMGCS2)

Short Description: The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
More information related to gene HMGCS2.

Products related to HMGCS2 Gene:

53 results :

Mouse HMGCS2 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_008256
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4446044
Datasheet
Catalog No. ABIN4446044
Type:
cDNA
Application:
Protein Expression
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_008256
Species:
Mouse
Synonyms:
HMGCS2, Hmgcs2, mvaS, CNC05080, HMCS1, hgsA, MFER_RS00425, LOC100285783, ECU10_0510, Eint_100450
Insert length:
1527 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat HMGCS2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_173094
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5235148
Datasheet
Catalog No. ABIN5235148
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_173094
Species:
Rat
Synonyms:
HMGCS2, Hmgcs2, mvaS, CNC05080, HMCS1, hgsA, MFER_RS00425, LOC100285783, ECU10_0510, Eint_100450
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Hmgcs2
Format:
Viral Particles
Storage:
-80 °C
Human HMGCS2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_005518
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5235144
Datasheet
Catalog No. ABIN5235144
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_005518
Species:
Human
Synonyms:
HMGCS2, Hmgcs2, mvaS, CNC05080, HMCS1, hgsA, MFER_RS00425, LOC100285783, ECU10_0510, Eint_100450
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of HMGCS2
Format:
Viral Particles
Storage:
-80 °C
Mouse HMGCS2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_008256
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5235146
Datasheet
Catalog No. ABIN5235146
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_008256
Species:
Mouse
Synonyms:
HMGCS2, Hmgcs2, mvaS, CNC05080, HMCS1, hgsA, MFER_RS00425, LOC100285783, ECU10_0510, Eint_100450
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Hmgcs2
Format:
Viral Particles
Storage:
-80 °C
Rat HMGCS2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_173094
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5119786
Datasheet
Catalog No. ABIN5119786
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_173094
Species:
Rat
Synonyms:
HMGCS2, Hmgcs2, mvaS, CNC05080, HMCS1, hgsA, MFER_RS00425, LOC100285783, ECU10_0510, Eint_100450
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Hmgcs2
Format:
Viral Particles
Storage:
-80 °C
Mouse HMGCS2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_008256
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5119784
Datasheet
Catalog No. ABIN5119784
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_008256
Species:
Mouse
Synonyms:
HMGCS2, Hmgcs2, mvaS, CNC05080, HMCS1, hgsA, MFER_RS00425, LOC100285783, ECU10_0510, Eint_100450
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Hmgcs2
Format:
Viral Particles
Storage:
-80 °C
Human HMGCS2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_005518
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5119782
Datasheet
Catalog No. ABIN5119782
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_005518
Species:
Human
Synonyms:
HMGCS2, Hmgcs2, mvaS, CNC05080, HMCS1, hgsA, MFER_RS00425, LOC100285783, ECU10_0510, Eint_100450
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of HMGCS2
Format:
Viral Particles
Storage:
-80 °C
Mouse HMGCS2 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_008256
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4645361
Datasheet
Catalog No. ABIN4645361
Type:
cDNA
Application:
Cloning
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_008256
Species:
Mouse
Synonyms:
HMGCS2, Hmgcs2, mvaS, CNC05080, HMCS1, hgsA, MFER_RS00425, LOC100285783, ECU10_0510, Eint_100450
Insert length:
1527 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse HMGCS2 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_008256
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4854841
Datasheet
Catalog No. ABIN4854841
Type:
cDNA
Application:
Cloning
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_008256
Species:
Mouse
Synonyms:
HMGCS2, Hmgcs2, mvaS, CNC05080, HMCS1, hgsA, MFER_RS00425, LOC100285783, ECU10_0510, Eint_100450
Insert length:
3294 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse HMGCS2 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_008256
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4412664
Datasheet
Catalog No. ABIN4412664
Type:
cDNA
Application:
Protein Expression
Gene:
3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2)
NCBI Accession:
NM_008256
Species:
Mouse
Synonyms:
HMGCS2, Hmgcs2, mvaS, CNC05080, HMCS1, hgsA, MFER_RS00425, LOC100285783, ECU10_0510, Eint_100450
Insert length:
1527 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL5
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
  • Insert
    • cDNA
    • shRNA
    • gRNA + Cas9
    • ORF
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to HMGCS2

  • 3-hydroxy-3-methylglutaryl-CoA synthase 2 (HMGCS2)
  • 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (Hmgcs2)
  • hydroxymethylglutaryl-CoA synthase (mvaS)
  • hydroxymethylglutaryl-CoA synthase (CNC05080)
  • hydroxymethylglutaryl-coa synthase (HMCS1)
  • hydroxymethylglutaryl-CoA synthase (hgsA)
  • hydroxymethylglutaryl-CoA synthase (MFER_RS00425)
  • hydroxymethylglutaryl-CoA synthase (LOC100285783)
  • 3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE 2 (ECU10_0510)
  • 3-hydroxy-3-methylglutaryl-CoA synthase 2 (Eint_100450)
  • 3-hydroxy-3-methylglutaryl-CoA synthase 2 (Hmgcs2)
  • 1300002P16
  • DDBDRAFT_0219349
  • DDBDRAFT_0219924
  • DDB_0219349
  • DDB_0219924
  • hmgCoA
  • Hmgcs1
  • mHS
  • Mt3h3mg

Gene-IDs for different species

Protein level used designations for HMGCS2

  • 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)
  • HMG-CoA synthase
  • hydroxymethylglutaryl-CoA synthase, mitochondrial
  • 3-hydroxy-3-methylglutaryl coenzyme A synthase
  • 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
  • hydroxymethylglutaryl-CoA synthase 2
  • hydroxymethylglutaryl-CoA synthase, mitochondrial-like
  • hydroxymethylglutaryl-CoA synthase
  • hydroxymethylglutaryl-coa synthase
  • GRMZM2G106263
  • putative hydroxymethylglutaryl-CoA synthase family protein
  • 3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE 2
  • 3-hydroxy-3-methylglutaryl-CoA synthase 2
  • 3-hydroxy-3-methylglutary-Coenzyme A synthase 2
Other products related to HMGCS2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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