IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble, IDH1)
Short Description: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. [provided by RefSeq, Jul 2008].
More information related to gene IDH1.
More information related to gene IDH1.
Products related to IDH1 Gene:
Recommended next Filters:
74 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1)
- NCBI Accession:
- NM_031510
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1)
- NCBI Accession:
- NM_010497
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1)
- NCBI Accession:
- NM_005896
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1)
- NCBI Accession:
- NM_005896
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1)
- NCBI Accession:
- NM_005896
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1)
- NCBI Accession:
- NM_031510
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
Synonyms and alternative names related to IDH1
- isocitrate dehydrogenase (NADP(+)) 1, cytosolic (IDH1)
- isocitrate dehydrogenase 1 (NADP+), soluble (Idh1)
- isocitrate dehydrogenase (NADP(+)) 1, cytosolic (Idh1)
- isocitrate dehydrogenase 1 (NADP+) L homeolog (idh1.L)
- isocitrate dehydrogenase 1 (NADP+), soluble (idh1)
- isocitrate dehydrogenase 1 (IDH1)
- AI314845
- AI788952
- cb876
- E030024J03Rik
- F23E12.180
- F23E12_180
- fm90e09
- Id-1
- IDCD
- IDH
- Idh-1
- IDH-I
- IDP
- IDPC
- Idpc
- im:7143416
- isocitrate dehydrogenase 1
- isocitrate dehydrogenase I
- NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 1
- NADP-CICDH
- PICD
- wu:fm90e09
Gene-IDs for different species
Protein level used designations for IDH1
- NADP(+)-specific ICDH
- NADP-dependent isocitrate dehydrogenase, cytosolic
- NADP-dependent isocitrate dehydrogenase, peroxisomal
- isocitrate dehydrogenase [NADP] cytoplasmic
- oxalosuccinate decarboxylase
- IDH
- IDP
- cytosolic NADP-isocitrate dehydrogenase
- isocitrate dehydrogenase 1 (NADP+), soluble
- isocitrate dehydrogenase [NADP] cytoplasmic-like
- Isocitrate dehydrogenase 1, soluble
- isocitrate dehydrogenase 1
- IDH-I
- Isocitric dehydrogenase 1
- NAD(+)-specific ICDH 1
Proteomics products related to IDH1 Gene
Other products related to IDH1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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