INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa, INPP5D)
Short Description: This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
More information related to gene INPP5D.
More information related to gene INPP5D.
Products related to INPP5D Gene:
Recommended next Filters:
84 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
- NCBI Accession:
- NM_010566
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
- NCBI Accession:
- NM_010566
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
- NCBI Accession:
- NM_005541
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
- NCBI Accession:
- NM_019311
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
- NCBI Accession:
- NM_010566
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
- NCBI Accession:
- NM_001017915
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
- NCBI Accession:
- NM_010566
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D)
- NCBI Accession:
- NM_010566
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
Synonyms and alternative names related to INPP5D
- inositol polyphosphate-5-phosphatase D (INPP5D)
- phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (LOC100446045)
- inositol polyphosphate-5-phosphatase D (inpp5d)
- inositol polyphosphate 5-phosphatase (EHI_159880)
- inositol polyphosphate 5-phosphatase (EHI_153490)
- inositol polyphosphate-5-phosphatase D L homeolog (inpp5d.L)
- phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (LOC100380693)
- inositol polyphosphate-5-phosphatase D (Inpp5d)
- 13.t00027
- 256.t00004
- AI323613
- hp51CN
- INPP5D
- s-SHIP
- ship
- SHIP
- SHIP-1
- ship1
- SHIP1
- SIP-145
Gene-IDs for different species
Protein level used designations for INPP5D
- inositol polyphosphate-5-phosphatase, 145kDa
- SH2 containing inositol phosphatase
- phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
- phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1-like
- SH2 domain-containing inositol 5'-phosphatase 1
- SH2 domain-containing inositol phosphatase 1
- SH2 domain-containing inositol-5'-phosphatase 1
- SHIP-1
- phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
- Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1
- SH2 containing inositol phosphotase
- SH2-containing inositol phosphatase SHIP
- SIP-145
- Src homology 2 domain-containing inositol-5-phosphatase
- inositol polyphosphate-5-phosphatase of 145 kDa
- inositol polyphosphate-5-phosphatase, 145 kDa
- p150Ship
- Inositol polyphosphate-5-phosphatase 145 kDa
- Inositol polyphosphate-5-phosphatase, 145 kDa
- signaling inositol polyphosphate 5 phosphatase SIP-145
Proteomics products related to INPP5D Gene
Other products related to INPP5D such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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