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ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog, ITCH)

Short Description: This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012].
More information related to gene ITCH.

Products related to ITCH Gene:

69 results :

Human ITCH ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5746996
Datasheet
Catalog No. ABIN5746996
Type:
ORF
Application:
Cloning
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
Species:
Human
Synonyms:
ITCH, Itch
Insert length:
2589 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse ITCH CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
NCBI Accession:
NM_001243712
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5246483
Datasheet
Catalog No. ABIN5246483
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
NCBI Accession:
NM_001243712
Species:
Mouse
Synonyms:
ITCH, Itch
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Itch
Format:
Viral Particles
Storage:
-80 °C
Rat ITCH CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
NCBI Accession:
NM_001005887
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5246485
Datasheet
Catalog No. ABIN5246485
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
NCBI Accession:
NM_001005887
Species:
Rat
Synonyms:
ITCH, Itch
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Itch
Format:
Viral Particles
Storage:
-80 °C
Human ITCH CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
NCBI Accession:
NM_031483
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5246481
Datasheet
Catalog No. ABIN5246481
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
NCBI Accession:
NM_031483
Species:
Human
Synonyms:
ITCH, Itch
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ITCH
Format:
Viral Particles
Storage:
-80 °C
Rat ITCH CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
NCBI Accession:
NM_001005887
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5131032
Datasheet
Catalog No. ABIN5131032
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
NCBI Accession:
NM_001005887
Species:
Rat
Synonyms:
ITCH, Itch
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Itch
Format:
Viral Particles
Storage:
-80 °C
Mouse ITCH CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
NCBI Accession:
NM_001243712
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5131030
Datasheet
Catalog No. ABIN5131030
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
NCBI Accession:
NM_001243712
Species:
Mouse
Synonyms:
ITCH, Itch
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Itch
Format:
Viral Particles
Storage:
-80 °C
Human ITCH CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
NCBI Accession:
NM_031483
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5131028
Datasheet
Catalog No. ABIN5131028
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
NCBI Accession:
NM_031483
Species:
Human
Synonyms:
ITCH, Itch
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ITCH
Format:
Viral Particles
Storage:
-80 °C
Mouse ITCH ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
NCBI Accession:
NM_008395
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5746997
Datasheet
Catalog No. ABIN5746997
Type:
ORF
Application:
Cloning
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
NCBI Accession:
NM_008395
Species:
Mouse
Synonyms:
ITCH, Itch
Insert length:
2595 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse ITCH ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
NCBI Accession:
NM_001243712
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5746998
Datasheet
Catalog No. ABIN5746998
Type:
ORF
Application:
Cloning
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
NCBI Accession:
NM_001243712
Species:
Mouse
Synonyms:
ITCH, Itch
Insert length:
2595 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat ITCH ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
NCBI Accession:
NM_001005887
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5746999
Datasheet
Catalog No. ABIN5746999
Type:
ORF
Application:
Cloning
Gene:
Itchy E3 Ubiquitin Protein Ligase Homolog (Mouse) (ITCH)
NCBI Accession:
NM_001005887
Species:
Rat
Synonyms:
ITCH, Itch
Insert length:
2565 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pCMV6-XL5
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to ITCH

  • itchy E3 ubiquitin protein ligase (ITCH)
  • itchy, E3 ubiquitin protein ligase (Itch)
  • itchy E3 ubiquitin protein ligase (Itch)
  • 6720481N21Rik
  • 8030492O04Rik
  • A130065M08
  • AIF4
  • AIP4
  • C230047C07Rik
  • dJ468O1.1
  • NAPP1

Gene-IDs for different species

Protein level used designations for ITCH

  • E3 ubiquitin-protein ligase Itchy homolog
  • NFE2-associated polypeptide 1
  • atrophin-1 interacting protein 4
  • dJ468O1.1 (atrophin 1 interacting protein 4 (AIP4))
  • itchy E3 ubiquitin protein ligase homolog
  • E3 ubiquitin-protein ligase Itchy
  • itch E3 ubiquitin ligase
  • itchy homolog E3 ubiquitin protein ligase
Other products related to ITCH such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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