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ITPK1 (Inositol-Tetrakisphosphate 1-Kinase, ITPK1)

Short Description: Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconverts the inositol tetrakisphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. Probably acts as the rate-limiting enzyme of the InsP6 pathway. Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain (By similarity). Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway.
More information related to gene ITPK1.

Products related to ITPK1 Gene:

66 results :

Human ITPK1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5751070
Datasheet
Catalog No. ABIN5751070
Type:
ORF
Application:
Cloning
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
Species:
Human
Synonyms:
ITPK1, Itpk1, itpk1.L, itpk1a
Insert length:
945 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human ITPK1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5751071
Datasheet
Catalog No. ABIN5751071
Type:
ORF
Application:
Cloning
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
Species:
Human
Synonyms:
ITPK1, Itpk1, itpk1.L, itpk1a
Insert length:
1245 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human ITPK1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4477078
Datasheet
Catalog No. ABIN4477078
Type:
cDNA
Application:
Protein Expression
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
Species:
Human
Synonyms:
ITPK1, Itpk1, itpk1.L, itpk1a
Insert length:
945 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human ITPK1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4477079
Datasheet
Catalog No. ABIN4477079
Type:
cDNA
Application:
Protein Expression
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
Species:
Human
Synonyms:
ITPK1, Itpk1, itpk1.L, itpk1a
Insert length:
945 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat ITPK1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
NCBI Accession:
NM_001191985
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5254649
Datasheet
Catalog No. ABIN5254649
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
NCBI Accession:
NM_001191985
Species:
Rat
Synonyms:
ITPK1, Itpk1, itpk1.L, itpk1a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Itpk1
Format:
Viral Particles
Storage:
-80 °C
Human ITPK1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
NCBI Accession:
XM_001726235
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5254645
Datasheet
Catalog No. ABIN5254645
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
NCBI Accession:
XM_001726235
Species:
Human
Synonyms:
ITPK1, Itpk1, itpk1.L, itpk1a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ITPK1
Format:
Viral Particles
Storage:
-80 °C
Mouse ITPK1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
NCBI Accession:
NM_172584
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5254647
Datasheet
Catalog No. ABIN5254647
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
NCBI Accession:
NM_172584
Species:
Mouse
Synonyms:
ITPK1, Itpk1, itpk1.L, itpk1a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Itpk1
Format:
Viral Particles
Storage:
-80 °C
Rat ITPK1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
NCBI Accession:
NM_001191985
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5139168
Datasheet
Catalog No. ABIN5139168
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
NCBI Accession:
NM_001191985
Species:
Rat
Synonyms:
ITPK1, Itpk1, itpk1.L, itpk1a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Itpk1
Format:
Viral Particles
Storage:
-80 °C
Human ITPK1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
NCBI Accession:
XM_001726235
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5139164
Datasheet
Catalog No. ABIN5139164
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
NCBI Accession:
XM_001726235
Species:
Human
Synonyms:
ITPK1, Itpk1, itpk1.L, itpk1a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ITPK1
Format:
Viral Particles
Storage:
-80 °C
Mouse ITPK1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
NCBI Accession:
NM_172584
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5139166
Datasheet
Catalog No. ABIN5139166
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
NCBI Accession:
NM_172584
Species:
Mouse
Synonyms:
ITPK1, Itpk1, itpk1.L, itpk1a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Itpk1
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pCas-Guide
    • pDONR223
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC
    • pCMV6-XL4
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to ITPK1

  • inositol-tetrakisphosphate 1-kinase (ITPK1)
  • inositol 1,3,4-triphosphate 5/6 kinase (Itpk1)
  • inositol-tetrakisphosphate 1-kinase L homeolog (itpk1.L)
  • inositol-tetrakisphosphate 1-kinase a (itpk1a)
  • inositol-tetrakisphosphate 1-kinase (Itpk1)
  • BC031182
  • ITRPK1
  • wu:fj15d08
  • zgc:56075

Gene-IDs for different species

Protein level used designations for ITPK1

  • inositol 1,3,4-triphosphate 5/6 kinase
  • inositol 1,3,4-trisphosphate 5/6 kinase
  • inositol 1,3,4-trisphosphate 5/6-kinase
  • inositol-triphosphate 5/6-kinase
  • ins(1,3,4)P(3) 5/6-kinase
  • inositol-tetrakisphosphate 1-kinase
Other products related to ITPK1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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