JNK (Mitogen-Activated Protein Kinase 8, MAPK8)
Short Description: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
More information related to gene JNK.
More information related to gene JNK.
Products related to JNK Gene:
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73 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Mitogen-Activated Protein Kinase 8 (MAPK8)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Mitogen-Activated Protein Kinase 8 (MAPK8)
- NCBI Accession:
- NM_016700
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Mitogen-Activated Protein Kinase 8 (MAPK8)
- NCBI Accession:
- NM_002750
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Mitogen-Activated Protein Kinase 8 (MAPK8)
- NCBI Accession:
- NM_002750
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Mitogen-Activated Protein Kinase 8 (MAPK8)
- NCBI Accession:
- NM_016700
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Mitogen-Activated Protein Kinase 8 (MAPK8)
- NCBI Accession:
- NM_016700
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Mitogen-Activated Protein Kinase 8 (MAPK8)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Mitogen-Activated Protein Kinase 8 (MAPK8)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Mitogen-Activated Protein Kinase 8 (MAPK8)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Mitogen-Activated Protein Kinase 8 (MAPK8)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
Synonyms and alternative names related to JNK
- mitogen-activated protein kinase 8 (MAPK8)
- Stress-activated protein kinase jnk-1 (jnk-1)
- mitogen-activated protein kinase 8 (Mapk8)
- basket (bsk)
- Protein kinase superfamily protein (ATMPK8)
- mitogen-activated protein kinase 8 L homeolog (mapk8.L)
- mitogen-activated protein kinase 8b (mapk8b)
- mitogen-activated protein kinase 8B-like (LOC109094263)
- AI849689
- BSK
- Bsk
- BSK/DJNK
- c-Jun
- CG5680
- D-JNK
- D-junk
- DBSK/JNK
- DJNK
- dJNK
- DJNK/bsk
- Dmel\\CG5680
- JNK
- Jnk
- jnk
- JNK-46
- JNK/SAPK
- JNK1
- jnk1
- JNK1A2
- JNK21B1/2
- JNKb
- Junk
- mapk8
- mapk8b
- PRKM8
- Prkm8
- SAPK1
- sapk1
- SAPK1c
- SAPKa
- T10F20.15
- zgc:112379
Gene-IDs for different species
Protein level used designations for JNK
- JUN N-terminal kinase
- MAP kinase 8
- c-Jun N-terminal kinase 1
- mitogen-activated protein kinase 8 isoform JNK1 alpha1
- mitogen-activated protein kinase 8 isoform JNK1 beta2
- stress-activated protein kinase 1
- stress-activated protein kinase 1c
- JNK1 beta1 protein kinase
- MAPK 8
- mitogen activated protein kinase 8
- protein kinase mitogen-activated 8
- stress-activated protein kinase JNK1
- SAPK gamma
- c-jun NH2-terminal kinase
- p54 gamma
- CG5680-PB
- CG5680-PE
- CG5680-PF
- JNK
- JUN kinase
- Jun N-terminal kinase
- Jun NH2-terminal kinase
- Jun-N-terminal kinase
- Jun-kinase
- bsk-PB
- bsk-PE
- bsk-PF
- c-Jun N-terminal kinase
- c-Jun aminoterminal kinase
- c-Jun-N-terminal kinase
- drosophila JNK
- janus kinase 1
- jnk1a-1
- mitogen-activated protein kinase 8
- LOW QUALITY PROTEIN: mitogen-activated protein kinase 8B-like
- MAP kinase 8B
- MAPK 8B
- Mitogen-activated protein kinase 8B
- Stress-activated protein kinase JNKb
- c-Jun N-terminal kinase B
Proteomics products related to JNK Gene
Other products related to JNK such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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