Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@genomics-online.com

LIG4 (Ligase IV, DNA, ATP-Dependent, LIG4)

Short Description: The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008].
More information related to gene LIG4.

Products related to LIG4 Gene:

65 results :

Human LIG4 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4477524
Datasheet
Catalog No. ABIN4477524
Type:
cDNA
Application:
Protein Expression
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
Species:
Human
Synonyms:
lig4, LIG4, LOC100212302, CpipJ_CPIJ005161, PTRG_09982, MCYG_05151, LOC657210, ATLIG4, lig4.L, Lig4
Insert length:
2736 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat LIG4 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
NCBI Accession:
NM_001106095
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5233238
Datasheet
Catalog No. ABIN5233238
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
NCBI Accession:
NM_001106095
Species:
Rat
Synonyms:
lig4, LIG4, LOC100212302, CpipJ_CPIJ005161, PTRG_09982, MCYG_05151, LOC657210, ATLIG4, lig4.L, Lig4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Lig4
Format:
Viral Particles
Storage:
-80 °C
Mouse LIG4 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
NCBI Accession:
NM_176953
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5233236
Datasheet
Catalog No. ABIN5233236
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
NCBI Accession:
NM_176953
Species:
Mouse
Synonyms:
lig4, LIG4, LOC100212302, CpipJ_CPIJ005161, PTRG_09982, MCYG_05151, LOC657210, ATLIG4, lig4.L, Lig4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Lig4
Format:
Viral Particles
Storage:
-80 °C
Human LIG4 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
NCBI Accession:
NM_001098268
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5233234
Datasheet
Catalog No. ABIN5233234
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
NCBI Accession:
NM_001098268
Species:
Human
Synonyms:
lig4, LIG4, LOC100212302, CpipJ_CPIJ005161, PTRG_09982, MCYG_05151, LOC657210, ATLIG4, lig4.L, Lig4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of LIG4
Format:
Viral Particles
Storage:
-80 °C
Rat LIG4 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
NCBI Accession:
NM_001106095
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5117878
Datasheet
Catalog No. ABIN5117878
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
NCBI Accession:
NM_001106095
Species:
Rat
Synonyms:
lig4, LIG4, LOC100212302, CpipJ_CPIJ005161, PTRG_09982, MCYG_05151, LOC657210, ATLIG4, lig4.L, Lig4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Lig4
Format:
Viral Particles
Storage:
-80 °C
Mouse LIG4 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
NCBI Accession:
NM_176953
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5117876
Datasheet
Catalog No. ABIN5117876
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
NCBI Accession:
NM_176953
Species:
Mouse
Synonyms:
lig4, LIG4, LOC100212302, CpipJ_CPIJ005161, PTRG_09982, MCYG_05151, LOC657210, ATLIG4, lig4.L, Lig4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Lig4
Format:
Viral Particles
Storage:
-80 °C
Human LIG4 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
NCBI Accession:
NM_001098268
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5117874
Datasheet
Catalog No. ABIN5117874
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
NCBI Accession:
NM_001098268
Species:
Human
Synonyms:
lig4, LIG4, LOC100212302, CpipJ_CPIJ005161, PTRG_09982, MCYG_05151, LOC657210, ATLIG4, lig4.L, Lig4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of LIG4
Format:
Viral Particles
Storage:
-80 °C
Human LIG4 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4834531
Datasheet
Catalog No. ABIN4834531
Type:
cDNA
Application:
Cloning
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
Species:
Human
Synonyms:
lig4, LIG4, LOC100212302, CpipJ_CPIJ005161, PTRG_09982, MCYG_05151, LOC657210, ATLIG4, lig4.L, Lig4
Insert length:
2736 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human LIG4 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4620995
Datasheet
Catalog No. ABIN4620995
Type:
cDNA
Application:
Cloning
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
Species:
Human
Synonyms:
lig4, LIG4, LOC100212302, CpipJ_CPIJ005161, PTRG_09982, MCYG_05151, LOC657210, ATLIG4, lig4.L, Lig4
Insert length:
2736 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human LIG4 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4705401
Datasheet
Catalog No. ABIN4705401
Type:
cDNA
Application:
Cloning
Gene:
Ligase IV, DNA, ATP-Dependent (LIG4)
Species:
Human
Synonyms:
lig4, LIG4, LOC100212302, CpipJ_CPIJ005161, PTRG_09982, MCYG_05151, LOC657210, ATLIG4, lig4.L, Lig4
Insert length:
2736 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pRFP-C-RS
    • pCMV6-XL5
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Viral Particles
    • Liquid

Synonyms and alternative names related to LIG4

  • ligase IV, DNA, ATP-dependent (lig4)
  • DNA ligase 4 (LIG4)
  • DNA ligase 4 (LOC100212302)
  • DNA ligase 4 (CpipJ_CPIJ005161)
  • DNA ligase 4 (PTRG_09982)
  • DNA ligase 4 (MCYG_05151)
  • DNA ligase 4 (LOC657210)
  • ATP-dependent DNA ligase implicated in dsDNA break repair via nonhomologous end-joining (LIG4)
  • DNA ligase IV (ATLIG4)
  • ligase IV, DNA, ATP-dependent L homeolog (lig4.L)
  • ligase IV, DNA, ATP-dependent (Lig4)
  • DNA ligase 4 (Lig4)
  • 5830471N16Rik
  • DNA LIGASE IV
  • DNL4
  • lig4
  • LIG4
  • lig4-A
  • tiny
  • zgc:165595

Gene-IDs for different species

Protein level used designations for LIG4

  • DNA ligase 4
  • ligase IV, DNA, ATP-dependent
  • DNA ligase IV
  • DNA ligase (ATP) 4
  • GLEAN_12219
  • ligase4-like protein
  • DNA ligase 4-like
  • dsDNA break repair ligase
  • polydeoxyribonucleotide synthase [ATP] 4
  • DNA joinase
  • DNA repair enzyme
  • polynucleotide ligase
  • sealase
Other products related to LIG4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
You are here:

antibodies-online

german

german (deutsch) antikoerper-online.de

english

english (english) antibodies-online.com

french

french (français) anticorps-enligne.fr

chinese

chinese (中文) antibodies-online.cn

genomics-online

english

english (english) genomics-online.com

Support