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MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor, MANF)

Short Description: The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors\; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related. [provided by RefSeq, Jun 2010].
More information related to gene MANF.

Products related to MANF Gene:

65 results :

Human MANF ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5735357
Datasheet
Catalog No. ABIN5735357
Type:
ORF
Application:
Cloning
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
Species:
Human
Synonyms:
MANF, Manf, RBM15B, manf, manf.S
Insert length:
549 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse MANF ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
NCBI Accession:
NM_029103
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5735359
Datasheet
Catalog No. ABIN5735359
Type:
ORF
Application:
Cloning
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
NCBI Accession:
NM_029103
Species:
Mouse
Synonyms:
MANF, Manf, RBM15B, manf, manf.S
Insert length:
540 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human MANF ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5735358
Datasheet
Catalog No. ABIN5735358
Type:
ORF
Application:
Cloning
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
Species:
Human
Synonyms:
MANF, Manf, RBM15B, manf, manf.S
Insert length:
558 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human MANF cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4472261
Datasheet
Catalog No. ABIN4472261
Type:
cDNA
Application:
Protein Expression
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
Species:
Human
Synonyms:
MANF, Manf, RBM15B, manf, manf.S
Insert length:
549 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse MANF cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
NCBI Accession:
NM_029103
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4448459
Datasheet
Catalog No. ABIN4448459
Type:
cDNA
Application:
Protein Expression
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
NCBI Accession:
NM_029103
Species:
Mouse
Synonyms:
MANF, Manf, RBM15B, manf, manf.S
Insert length:
540 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat MANF CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
NCBI Accession:
NM_001108183
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5108951
Datasheet
Catalog No. ABIN5108951
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
NCBI Accession:
NM_001108183
Species:
Rat
Synonyms:
MANF, Manf, RBM15B, manf, manf.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Manf
Format:
Viral Particles
Storage:
-80 °C
Mouse MANF CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
NCBI Accession:
NM_029103
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5108949
Datasheet
Catalog No. ABIN5108949
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
NCBI Accession:
NM_029103
Species:
Mouse
Synonyms:
MANF, Manf, RBM15B, manf, manf.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Manf
Format:
Viral Particles
Storage:
-80 °C
Human MANF CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
NCBI Accession:
NM_006010
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5108945
Datasheet
Catalog No. ABIN5108945
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
NCBI Accession:
NM_006010
Species:
Human
Synonyms:
MANF, Manf, RBM15B, manf, manf.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ARMET
Format:
Viral Particles
Storage:
-80 °C
Human MANF CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
NCBI Accession:
NM_006010
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5108947
Datasheet
Catalog No. ABIN5108947
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
NCBI Accession:
NM_006010
Species:
Human
Synonyms:
MANF, Manf, RBM15B, manf, manf.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of MANF
Format:
Viral Particles
Storage:
-80 °C
Human MANF cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4758636
Datasheet
Catalog No. ABIN4758636
Type:
cDNA
Application:
Cloning
Gene:
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF)
Species:
Human
Synonyms:
MANF, Manf, RBM15B, manf, manf.S
Insert length:
549 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • ProteoGenix
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCas-Guide
    • pDONR223
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pPB-His-GST
    • pPB-His-MBP
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to MANF

  • mesencephalic astrocyte derived neurotrophic factor (MANF)
  • mesencephalic astrocyte-derived neurotrophic factor (Manf)
  • RNA binding motif protein 15B (RBM15B)
  • Mesencephalic astrocyte-derived neurotrophic factor (Manf)
  • mesencephalic astrocyte-derived neurotrophic factor (manf)
  • mesencephalic astrocyte derived neurotrophic factor (Manf)
  • mesencephalic astrocyte-derived neurotrophic factor S homeolog (manf.S)
  • 3230402M22Rik
  • AA407711
  • AA408789
  • AA673178
  • anon-EST:ParkEST188
  • ARMET
  • Armet
  • armet
  • ARP
  • arp
  • ARP-like
  • CG7013
  • D18Mgi17
  • D17914
  • Dmel\\CG7013
  • DmMANF
  • im:6909481
  • MANF
  • manf
  • RBM15B
  • zgc:153327

Gene-IDs for different species

Protein level used designations for MANF

  • arginine-rich, mutated in early stage tumors
  • arginine-rich protein
  • mesencephalic astrocyte-derived neurotrophic factor
  • RNA binding motif protein 15B
  • chromosome 3p21.1 gene sequence
  • CG7013-PA
  • Manf-PA
  • ARP-like
  • LOW QUALITY PROTEIN: mesencephalic astrocyte-derived neurotrophic factor
  • mesencephalic astrocyte-derived neurotrophic factor S homeolog
Other products related to MANF such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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