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MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4, MAP4K4)

Short Description: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
More information related to gene MAP4K4.

Products related to MAP4K4 Gene:

73 results :

Rat MAP4K4 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_001106904
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5236178
Datasheet
Catalog No. ABIN5236178
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_001106904
Species:
Rat
Synonyms:
MAP4K4, Map4k4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Map4k4
Format:
Viral Particles
Storage:
-80 °C
Mouse MAP4K4 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_008696
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5236176
Datasheet
Catalog No. ABIN5236176
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_008696
Species:
Mouse
Synonyms:
MAP4K4, Map4k4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Map4k4
Format:
Viral Particles
Storage:
-80 °C
Human MAP4K4 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_145687
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5236174
Datasheet
Catalog No. ABIN5236174
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_145687
Species:
Human
Synonyms:
MAP4K4, Map4k4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of MAP4K4
Format:
Viral Particles
Storage:
-80 °C
Rat MAP4K4 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_001106904
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120814
Datasheet
Catalog No. ABIN5120814
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_001106904
Species:
Rat
Synonyms:
MAP4K4, Map4k4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Map4k4
Format:
Viral Particles
Storage:
-80 °C
Mouse MAP4K4 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_008696
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120812
Datasheet
Catalog No. ABIN5120812
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_008696
Species:
Mouse
Synonyms:
MAP4K4, Map4k4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Map4k4
Format:
Viral Particles
Storage:
-80 °C
Human MAP4K4 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_145687
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120810
Datasheet
Catalog No. ABIN5120810
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_145687
Species:
Human
Synonyms:
MAP4K4, Map4k4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of MAP4K4
Format:
Viral Particles
Storage:
-80 °C
Mouse MAP4K4 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_008696
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5741581
Datasheet
Catalog No. ABIN5741581
Type:
ORF
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_008696
Species:
Mouse
Synonyms:
MAP4K4, Map4k4
Insert length:
3705 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat MAP4K4 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_001106904
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5741585
Datasheet
Catalog No. ABIN5741585
Type:
ORF
Application:
Cloning
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_001106904
Species:
Rat
Synonyms:
MAP4K4, Map4k4
Insert length:
3537 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat MAP4K4 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_001106904
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5236177
Datasheet
Catalog No. ABIN5236177
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_001106904
Species:
Rat
Synonyms:
MAP4K4, Map4k4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Map4k4
Format:
Viral Particles
Storage:
-80 °C
Mouse MAP4K4 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_008696
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5236175
Datasheet
Catalog No. ABIN5236175
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)
NCBI Accession:
NM_008696
Species:
Mouse
Synonyms:
MAP4K4, Map4k4
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Map4k4
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-XL4
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to MAP4K4

  • mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4)
  • mitogen-activated protein kinase kinase kinase kinase 4 (Map4k4)
  • 9430080K19Rik
  • AU043147
  • AU045934
  • AW046177
  • FLH21957
  • HGK
  • MEKKK4
  • NIK
  • Nik

Gene-IDs for different species

Protein level used designations for MAP4K4

  • HPK/GCK-like kinase HGK
  • MAPK/ERK kinase kinase kinase 4
  • MEK kinase kinase 4
  • Ste20 group protein kinase HGK
  • hepatocyte progenitor kinase-like/germinal center kinase-like kinase
  • nck-interacting kinase
  • MEKKK 4
  • NCK interacting kinase
  • mitogen activated protein kinase kinase kinase kinase 4
Other products related to MAP4K4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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