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MECOM (MDS1 and EVI1 Complex Locus, MECOM)

Short Description: The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].
More information related to gene MECOM.

Products related to MECOM Gene:

103 results :

Human MECOM ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5756931
Datasheet
Catalog No. ABIN5756931
Type:
ORF
Application:
Cloning
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
Species:
Human
Synonyms:
MECOM, Mecom, mecom, mecom.L, mecom.S
Insert length:
510 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human MECOM cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4477945
Datasheet
Catalog No. ABIN4477945
Type:
cDNA
Application:
Protein Expression
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
Species:
Human
Synonyms:
MECOM, Mecom, mecom, mecom.L, mecom.S
Insert length:
510 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human MECOM CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
NCBI Accession:
NM_001105077
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150727
Datasheet
Catalog No. ABIN5150727
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
NCBI Accession:
NM_001105077
Species:
Human
Synonyms:
MECOM, Mecom, mecom, mecom.L, mecom.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of MECOM
Format:
Viral Particles
Storage:
-80 °C
Human MECOM CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
NCBI Accession:
NM_005241
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150723
Datasheet
Catalog No. ABIN5150723
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
NCBI Accession:
NM_005241
Species:
Human
Synonyms:
MECOM, Mecom, mecom, mecom.L, mecom.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of EVI1
Format:
Viral Particles
Storage:
-80 °C
Rat MECOM CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
NCBI Accession:
NM_001106423
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150731
Datasheet
Catalog No. ABIN5150731
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
NCBI Accession:
NM_001106423
Species:
Rat
Synonyms:
MECOM, Mecom, mecom, mecom.L, mecom.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Mecom
Format:
Viral Particles
Storage:
-80 °C
Mouse MECOM CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
NCBI Accession:
NM_007963
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150729
Datasheet
Catalog No. ABIN5150729
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
NCBI Accession:
NM_007963
Species:
Mouse
Synonyms:
MECOM, Mecom, mecom, mecom.L, mecom.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Mecom
Format:
Viral Particles
Storage:
-80 °C
Human MECOM CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
NCBI Accession:
NM_004991
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150725
Datasheet
Catalog No. ABIN5150725
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
NCBI Accession:
NM_004991
Species:
Human
Synonyms:
MECOM, Mecom, mecom, mecom.L, mecom.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of MDS1
Format:
Viral Particles
Storage:
-80 °C
Human MECOM cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4621416
Datasheet
Catalog No. ABIN4621416
Type:
cDNA
Application:
Cloning
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
Species:
Human
Synonyms:
MECOM, Mecom, mecom, mecom.L, mecom.S
Insert length:
510 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human MECOM cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4439040
Datasheet
Catalog No. ABIN4439040
Type:
cDNA
Application:
Protein Expression
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
Species:
Human
Synonyms:
MECOM, Mecom, mecom, mecom.L, mecom.S
Insert length:
510 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat MECOM ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
NCBI Accession:
NM_001106423
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5756934
Datasheet
Catalog No. ABIN5756934
Type:
ORF
Application:
Cloning
Gene:
MDS1 and EVI1 Complex Locus (MECOM)
NCBI Accession:
NM_001106423
Species:
Rat
Synonyms:
MECOM, Mecom, mecom, mecom.L, mecom.S
Insert length:
2754 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pRS
    • pCMV6-XL5
    • pCas-Guide
    • pRFP-C-RS
    • pCMV6-XL6
    • pDONR223
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
    • SP6 Promoter
  • Format
    • Lyophilized
    • Viral Particles
    • Liquid

Synonyms and alternative names related to MECOM

  • MDS1 and EVI1 complex locus (MECOM)
  • MDS1 and EVI1 complex locus (Mecom)
  • MDS1 and EVI1 complex locus (mecom)
  • MDS1 and EVI1 complex locus L homeolog (mecom.L)
  • MDS1 and EVI1 complex locus S homeolog (mecom.S)
  • AML1-EVI-1
  • D630039M04Rik
  • Evi-1
  • evi-1
  • EVI1
  • Evi1
  • evi1
  • evi1-B
  • im:7140716
  • Jbo
  • Mds
  • MDS1
  • Mds1
  • MDS1-EVI1
  • Mds1-Evi1
  • mecom
  • mecom-a
  • mecom-b
  • PRDM3
  • Prdm3
  • prdm3
  • xEvi-1
  • Znfpr1b1

Gene-IDs for different species

Protein level used designations for MECOM

  • AML1-EVI-1 fusion protein
  • MDS1 and EVI1 complex locus protein EVI1
  • MDS1 and EVI1 complex locus protein MDS1
  • ecotropic virus integration site 1 protein homolog
  • myelodysplasia syndrome-associated protein 1
  • oncogene EVI1
  • zinc finger protein Evi1
  • ecotropic viral integration site 1
  • ecotropic virus integration site 1 protein
  • myelodysplasia syndrome 1 homolog
  • myelodysplasia syndrome 1 protein homolog
  • PR domain containing 3
  • MDS1 and EVI1 complex locus
  • MDS1 and EVI1 complex locus protein EVI1-like
  • MDS1 and EVI1 complex locus protein EVI1-A
  • ecotropic virus integration site 1 protein homolog-A
  • myelodysplasia syndrome 1-ectopic viral integration site 1
  • Ecotropic virus integration site 1 protein homolog-B
  • MDS1 and EVI1 complex locus protein EVI1-B
Other products related to MECOM such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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