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Melanoma gp100 (Premelanosome Protein, PMEL)

Short Description: This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011].
More information related to gene Melanoma gp100.

Products related to Melanoma gp100 Gene:

63 results :

Human PMEL ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Premelanosome Protein (PMEL)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5764228
Datasheet
Catalog No. ABIN5764228
Type:
ORF
Application:
Cloning
Gene:
Premelanosome Protein (PMEL)
Species:
Human
Synonyms:
PMEL, Pmel, pmelb, pmela
Insert length:
1986 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human PMEL cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Premelanosome Protein (PMEL)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4481112
Datasheet
Catalog No. ABIN4481112
Type:
cDNA
Application:
Protein Expression
Gene:
Premelanosome Protein (PMEL)
Species:
Human
Synonyms:
PMEL, Pmel, pmelb, pmela
Insert length:
1986 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse PMEL CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Premelanosome Protein (PMEL)
NCBI Accession:
NM_021882
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5164900
Datasheet
Catalog No. ABIN5164900
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Premelanosome Protein (PMEL)
NCBI Accession:
NM_021882
Species:
Mouse
Synonyms:
PMEL, Pmel, pmelb, pmela
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Pmel
Format:
Viral Particles
Storage:
-80 °C
Human PMEL CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Premelanosome Protein (PMEL)
NCBI Accession:
NM_001200053
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5164898
Datasheet
Catalog No. ABIN5164898
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Premelanosome Protein (PMEL)
NCBI Accession:
NM_001200053
Species:
Human
Synonyms:
PMEL, Pmel, pmelb, pmela
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PMEL
Format:
Viral Particles
Storage:
-80 °C
Rat PMEL CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Premelanosome Protein (PMEL)
NCBI Accession:
NM_001108729
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5164902
Datasheet
Catalog No. ABIN5164902
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Premelanosome Protein (PMEL)
NCBI Accession:
NM_001108729
Species:
Rat
Synonyms:
PMEL, Pmel, pmelb, pmela
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Pmel
Format:
Viral Particles
Storage:
-80 °C
Human PMEL CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Premelanosome Protein (PMEL)
NCBI Accession:
NM_006928
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5164896
Datasheet
Catalog No. ABIN5164896
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Premelanosome Protein (PMEL)
NCBI Accession:
NM_006928
Species:
Human
Synonyms:
PMEL, Pmel, pmelb, pmela
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SILV
Format:
Viral Particles
Storage:
-80 °C
Human PMEL cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Premelanosome Protein (PMEL)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4624583
Datasheet
Catalog No. ABIN4624583
Type:
cDNA
Application:
Cloning
Gene:
Premelanosome Protein (PMEL)
Species:
Human
Synonyms:
PMEL, Pmel, pmelb, pmela
Insert length:
1986 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human PMEL cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Premelanosome Protein (PMEL)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4416026
Datasheet
Catalog No. ABIN4416026
Type:
cDNA
Application:
Protein Expression
Gene:
Premelanosome Protein (PMEL)
Species:
Human
Synonyms:
PMEL, Pmel, pmelb, pmela
Insert length:
1986 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse PMEL ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Premelanosome Protein (PMEL)
NCBI Accession:
NM_021882
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5764226
Datasheet
Catalog No. ABIN5764226
Type:
ORF
Application:
Cloning
Gene:
Premelanosome Protein (PMEL)
NCBI Accession:
NM_021882
Species:
Mouse
Synonyms:
PMEL, Pmel, pmelb, pmela
Insert length:
1881 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat PMEL ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Premelanosome Protein (PMEL)
NCBI Accession:
NM_001108729
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5764227
Datasheet
Catalog No. ABIN5764227
Type:
ORF
Application:
Cloning
Gene:
Premelanosome Protein (PMEL)
NCBI Accession:
NM_001108729
Species:
Rat
Synonyms:
PMEL, Pmel, pmelb, pmela
Insert length:
1257 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC-GFP
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pRS
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • gRNA + Cas9
    • gRNA
    • shRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • PGK Promoter
    • SFFV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Viral Particles
    • Liquid

Synonyms and alternative names related to Melanoma gp100

  • premelanosome protein (PMEL)
  • premelanosome protein (Pmel)
  • premelanosome protein b (pmelb)
  • premelanosome protein a (pmela)
  • cb397
  • D10H12S53E
  • D12S53E
  • D12S53Eh
  • fdv
  • gp87
  • gp100
  • ME20
  • ME20-M
  • ME20M
  • MMP115
  • P1
  • P100
  • PMEL17
  • Pmel17
  • pmel17
  • RPE1
  • sb:cb397
  • SI
  • Si
  • SIL
  • SILV
  • Silv
  • silva
  • silver
  • silverb
  • wu:fc11g11
  • wu:fj24g11
  • zgc:136622

Gene-IDs for different species

Protein level used designations for Melanoma gp100

  • melanocyte protein PMEL
  • melanocyte protein Pmel 17
  • melanocyte protein mel 17
  • melanocytes lineage-specific antigen GP100
  • melanoma-associated ME20 antigen
  • melanosomal matrix protein17
  • silver locus protein homolog
  • silver, mouse, homolog of
  • melanocyte protein pmel 17
  • silver locus protein
  • retinal pigment epithelial-specific protein
  • silver homolog
  • 115 kDa melanosomal matrix protein
  • PMEL17 protein
  • melanosome matrix protein
  • melanocyte protein 17
  • premelanosomal protein
  • fading vision
  • melanosomal matrix protein
  • silver homolog a
Other products related to Melanoma gp100 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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