Mre11 (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae), MRE11A)
Short Description: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog\; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
More information related to gene Mre11.
More information related to gene Mre11.
Products related to Mre11 Gene:
Recommended next Filters:
63 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A)
- NCBI Accession:
- NM_022279
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A)
- NCBI Accession:
- NM_018736
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A)
- NCBI Accession:
- NM_005590
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A)
- NCBI Accession:
- NM_022279
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A)
- NCBI Accession:
- NM_018736
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A)
- NCBI Accession:
- NM_005590
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
Synonyms and alternative names related to Mre11
- MRE11 homolog A, double strand break repair nuclease (mre11a)
- MRE11 homolog, double strand break repair nuclease (MRE11)
- MRE11A homolog A, double strand break repair nuclease (Mre11a)
- MRE11 homolog A, double strand break repair nuclease (Mre11a)
- ATLD
- HNGS1
- Mre11
- MRE11
- Mre11b
- MRE11B
- wu:faa63d12
- zgc:64018
Gene-IDs for different species
Protein level used designations for Mre11
- meiotic recombination 11 homolog A
- MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
- MRE11 homolog 1
- MRE11 homolog A
- double-strand break repair protein MRE11A
- meiotic recombination 11 homolog 1
- mmMRE11A
- AT-like disease
- DNA recombination and repair protein
- endo/exonuclease Mre11
- meiotic recombination 11-like protein
Proteomics products related to Mre11 Gene
Other products related to Mre11 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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