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NEDD4-2 (E3 ubiquitin-protein ligase NEDD4-like, NEDD4L)

Short Description: This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012].
More information related to gene NEDD4-2.

Products related to NEDD4-2 Gene:

81 results :

Human NEDD4L ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5756163
Datasheet
Catalog No. ABIN5756163
Type:
ORF
Application:
Cloning
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
Species:
Human
Synonyms:
NEDD4L, LOC776799, nedd4l.S, Nedd4l
Insert length:
2736 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human NEDD4L cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4478602
Datasheet
Catalog No. ABIN4478602
Type:
cDNA
Application:
Protein Expression
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
Species:
Human
Synonyms:
NEDD4L, LOC776799, nedd4l.S, Nedd4l
Insert length:
2736 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat NEDD4L CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_001008300
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5264887
Datasheet
Catalog No. ABIN5264887
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_001008300
Species:
Rat
Synonyms:
NEDD4L, LOC776799, nedd4l.S, Nedd4l
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Nedd4l
Format:
Viral Particles
Storage:
-80 °C
Mouse NEDD4L CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_031881
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5264885
Datasheet
Catalog No. ABIN5264885
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_031881
Species:
Mouse
Synonyms:
NEDD4L, LOC776799, nedd4l.S, Nedd4l
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Nedd4l
Format:
Viral Particles
Storage:
-80 °C
Human NEDD4L CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_015277
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5264883
Datasheet
Catalog No. ABIN5264883
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_015277
Species:
Human
Synonyms:
NEDD4L, LOC776799, nedd4l.S, Nedd4l
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of NEDD4L
Format:
Viral Particles
Storage:
-80 °C
Rat NEDD4L CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_001008300
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5149341
Datasheet
Catalog No. ABIN5149341
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_001008300
Species:
Rat
Synonyms:
NEDD4L, LOC776799, nedd4l.S, Nedd4l
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Nedd4l
Format:
Viral Particles
Storage:
-80 °C
Human NEDD4L CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_015277
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5149337
Datasheet
Catalog No. ABIN5149337
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_015277
Species:
Human
Synonyms:
NEDD4L, LOC776799, nedd4l.S, Nedd4l
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of NEDD4L
Format:
Viral Particles
Storage:
-80 °C
Mouse NEDD4L CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_031881
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5149339
Datasheet
Catalog No. ABIN5149339
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
NCBI Accession:
NM_031881
Species:
Mouse
Synonyms:
NEDD4L, LOC776799, nedd4l.S, Nedd4l
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Nedd4l
Format:
Viral Particles
Storage:
-80 °C
Human NEDD4L cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4836039
Datasheet
Catalog No. ABIN4836039
Type:
cDNA
Application:
Cloning
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
Species:
Human
Synonyms:
NEDD4L, LOC776799, nedd4l.S, Nedd4l
Insert length:
2736 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human NEDD4L cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4622073
Datasheet
Catalog No. ABIN4622073
Type:
cDNA
Application:
Cloning
Gene:
Neural Precursor Cell Expressed, Developmentally Down-Regulated 4-Like (NEDD4L)
Species:
Human
Synonyms:
NEDD4L, LOC776799, nedd4l.S, Nedd4l
Insert length:
2736 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCas-Guide
    • pCMV6-XL4
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Spectinomycin
    • Chloramphenicol
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to NEDD4-2

  • neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase (NEDD4L)
  • NEDD4L (LOC776799)
  • neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase S homeolog (nedd4l.S)
  • neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase (Nedd4l)
  • neural precursor cell expressed, developmentally down-regulated gene 4-like (Nedd4l)
  • 1300012C07Rik
  • hNEDD4-2
  • nedd4
  • NEDD4
  • NEDD4-2
  • nedd4-2
  • Nedd4-2
  • NEDD4.2
  • Nedd4b
  • RSP5

Gene-IDs for different species

Protein level used designations for NEDD4-2

  • E3 ubiquitin-protein ligase NEDD4-like
  • E3 ubiquitin-protein ligase NEDD4-like protein
  • ubiquitin-protein ligase Rsp5
  • neural precursor cell expressed, developmentally down-regulated 4
  • NEDD4.2
  • neural precursor cell expressed, developmentally down-regulated gene 4b
Other products related to NEDD4-2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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