NFkB (Nuclear Factor kappa B, NFkB)
Short Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
More information related to gene NFkB.
More information related to gene NFkB.
Products related to NFkB Gene:
Recommended next Filters:
4 results :
gRNA + Cas9
GEEN, PExp
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases, Protein Expression
- Gene:
- Nuclear Factor kappa B (NFkB)
- NCBI Accession:
- NM_008689
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA
GEEN, PExp
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Genome Editing with Engineered Nucleases, Protein Expression
- Gene:
- Nuclear Factor kappa B (NFkB)
- NCBI Accession:
- NM_008689
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
GEEN, PExp
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases, Protein Expression
- Gene:
- Nuclear Factor kappa B (NFkB)
- NCBI Accession:
- NM_008689
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA
GEEN, PExp
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Genome Editing with Engineered Nucleases, Protein Expression
- Gene:
- Nuclear Factor kappa B (NFkB)
- NCBI Accession:
- NM_008689
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
Synonyms and alternative names related to NFkB
- nuclear factor kappa B subunit 1 (NFKB1)
- nuclear factor kappa B subunit 1 (Nfkb1)
- nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 (Nfkb1)
- EBP-1
- KBF1
- NF-kappa-B
- NF-kappaB
- NF-kappaB1
- NF-kB
- NF-kB1
- NF-KB1
- NFkappaB
- NFKB-p50
- NFKB-p105
- p50
- p50/p105
- p105
Gene-IDs for different species
Protein level used designations for NFkB
- DNA binding factor KBF1
- DNA-binding factor KBF1
- NF-kappabeta
- nuclear factor NF-kappa-B p105 subunit
- nuclear factor NF-kappa-B p50 subunit
- nuclear factor kappa-B DNA binding subunit
- nuclear factor of kappa light chain gene enhancer in B-cells 1, p105
- nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
- NF-kB p50 subunit
- nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)
- nuclear factor kappa-B 1
- EBP-1
- NF kappaB1
- NF-kappa-B1 p84/NF-kappa-B1 p98
- NF-kappaB p50
- nuclear factor kappaB p50
- nuclear factor-kappaB p50
- p50 subunit of NF kappaB
- p50 subunit of NF-kappaB
Proteomics products related to NFkB Gene
Other products related to NFkB such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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