OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa, OAS1)
Short Description: This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
More information related to gene OAS1.
More information related to gene OAS1.
Products related to OAS1 Gene:
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38 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- 2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- 2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- 2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- 2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- 2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1)
- NCBI Accession:
- NM_016816
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- 2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- 2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- 2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-His
Kanamycin
CMV Promoter
His tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- 2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-His
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- His tag
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- 2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1)
- NCBI Accession:
- NM_016816
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Synonyms and alternative names related to OAS1
- 2',5'-oligoadenylate synthetase 1 (OAS1)
- 2'-5'-oligoadenylate synthetase 1 (OAS1)
- 2'-5' oligoadenylate synthetase 1A (Oas1a)
- protein phosphatase 2 catalytic subunit beta (Ppp2cb)
- 2'-5'-oligoadenylate synthetase 1 (Oas1)
- IFI-4
- L3
- OAS1
- OIAS
- OIASI
- Pp2a2
Gene-IDs for different species
Protein level used designations for OAS1
- 2',5'-oligoadenylate synthetase 1
- 2',5'-oligoadenylate synthetase 1, 40/46kDa
- 2'-5'-oligoadenylate synthase 1
- (2-5')oligo(A) synthase 1
- (2-5')oligo(A) synthetase 1
- 2'-5' oligoadenylate synthetase
- 2-5A synthase 1
- 2-5A synthetase 1
- p42 OAS
- 2-5-oligoadenylate synthetase 1
- 2'-5' oligoadenylate synthetase 1
- 2',5'-oligo A synthetase 1
- 2'-5' oligoadenylate synthetase 1 p48 isoform
- 2'-5' oligoadenylate synthetase 1 p52 isoform
- 2'-5'-oligoisoadenylate synthetase 1
- E18/E16
- p46/p42 OAS
- 2'-5'-oligoadenylate synthetase 1-like
- 2'-5'-oligoadenylate synthetase 1, 40/46kDa
- (2-5')oligo(A) synthase 1A
- (2-5')oligo(A) synthetase 1A
- 2'-5'-oligoadenylate synthase 1A
- 2-5A synthase 1A
- 2-5A synthetase 1A
- PP2A-beta
- protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
- protein phosphatase 2, catalytic subunit, beta isoform
- protein phosphatase 2A catalytic alpha subunit
- protein phosphatase 2a, catalytic subunit, beta isoform
- protein phosphatase-2A-beta
- serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
- LOW QUALITY PROTEIN: 2'-5'-oligoadenylate synthase 1
Proteomics products related to OAS1 Gene
Other products related to OAS1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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