OAS1B (2'-5' Oligoadenylate Synthetase 1B, OAS1B)
Short Description: This gene is a member of the 2'-5' oligoA synthetase family, which are clustered on chromosome 5. The encoded protein functions in the interferon-regulated OAS/RNase L system, which mediates RNA decay as part of the innate antiviral immunity pathway. The protein binds double-stranded RNA and oligomerizes ATP, which activate the single-stranded RNA cleavage enzyme RNase L. This protein mediates resistance to flaviviruses such as West Nile virus. The majority of wild mouse strains produce a functional protein and are resistant to flavivirus infection, whereas some inbred mouse strains including the strain of the reference genome, C57BL/6J, contain a premature stop codon that inactivates this gene product. [provided by RefSeq, Jul 2008].
More information related to gene OAS1B.
More information related to gene OAS1B.
Products related to OAS1B Gene:
Recommended next Filters:
34 results :
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- 2'-5' Oligoadenylate Synthetase 1B (OAS1B)
- NCBI Accession:
- NM_144752
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- 2'-5' Oligoadenylate Synthetase 1B (OAS1B)
- NCBI Accession:
- NM_001083925
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- 2'-5' Oligoadenylate Synthetase 1B (OAS1B)
- NCBI Accession:
- NM_144752
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- 2'-5' Oligoadenylate Synthetase 1B (OAS1B)
- NCBI Accession:
- NM_001083925
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- 2'-5' Oligoadenylate Synthetase 1B (OAS1B)
- NCBI Accession:
- NM_001083925
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- 2'-5' Oligoadenylate Synthetase 1B (OAS1B)
- NCBI Accession:
- NM_144752
- Species:
- Rat
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- 2'-5' Oligoadenylate Synthetase 1B (OAS1B)
- NCBI Accession:
- NM_144752
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- 2'-5' Oligoadenylate Synthetase 1B (OAS1B)
- NCBI Accession:
- NM_001083925
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- 2'-5' Oligoadenylate Synthetase 1B (OAS1B)
- NCBI Accession:
- NM_144752
- Species:
- Rat
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- 2'-5' Oligoadenylate Synthetase 1B (OAS1B)
- NCBI Accession:
- NM_001083925
- Species:
- Mouse
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
Synonyms and alternative names related to OAS1B
- 2'-5' oligoadenylate synthetase 1B (Oas1b)
- 2-5 oligoadenylate synthetase 1B (Oas1b)
- (2-5')oligo(A) synthase 1B
- 2-5A synthase 1B
- Flv
- L1
- Mmu-L1
- Oas1
- Oias-2
- Oias2
- Wnv
Gene-IDs for different species
Protein level used designations for OAS1B
- (2-5')oligo(A) synthase 1B
- (2-5')oligo(A) synthetase 1b
- 2',5'-oligoadenylate synthetase-like 1
- 2'-5'-oligoadenylate synthase 1B
- 2'-5'-oligoadenylate synthase-like protein 1
- 2'-5'-oligoadenylate synthetase-like protein 1
- 2-5A synthase 1B
- 2-5A synthetase 1B
- Flavivirus resistance
- inactive 2'-5'-oligoadenylate synthase 1B
- 2'5' oligoadenylate synthetase-2
- 25 oligoadenylate synthetase-2
Proteomics products related to OAS1B Gene
Other products related to OAS1B such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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