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OPA1 (Optic Atrophy 1 (Autosomal Dominant), OPA1)

Short Description: This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
More information related to gene OPA1.

Products related to OPA1 Gene:

92 results :

Rat OPA1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_133585
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5734512
Datasheet
Catalog No. ABIN5734512
Type:
ORF
Application:
Cloning
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_133585
Species:
Rat
Synonyms:
Opa1, OPA1, opa1
Insert length:
3200 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human OPA1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_130837
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5734509
Datasheet
Catalog No. ABIN5734509
Type:
ORF
Application:
Cloning
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_130837
Species:
Human
Synonyms:
Opa1, OPA1, opa1
Insert length:
831 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat OPA1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_133585
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4468099
Datasheet
Catalog No. ABIN4468099
Type:
cDNA
Application:
Protein Expression
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_133585
Species:
Rat
Synonyms:
Opa1, OPA1, opa1
Insert length:
3200 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human OPA1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_130837
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4489349
Datasheet
Catalog No. ABIN4489349
Type:
cDNA
Application:
Protein Expression
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_130837
Species:
Human
Synonyms:
Opa1, OPA1, opa1
Insert length:
831 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat OPA1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_022260
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5107431
Datasheet
Catalog No. ABIN5107431
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_022260
Species:
Rat
Synonyms:
Opa1, OPA1, opa1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Opa1
Format:
Viral Particles
Storage:
-80 °C
Mouse OPA1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_133752
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5107429
Datasheet
Catalog No. ABIN5107429
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_133752
Species:
Mouse
Synonyms:
Opa1, OPA1, opa1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Opa1
Format:
Viral Particles
Storage:
-80 °C
Human OPA1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_015560
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5107427
Datasheet
Catalog No. ABIN5107427
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_015560
Species:
Human
Synonyms:
Opa1, OPA1, opa1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of OPA1
Format:
Viral Particles
Storage:
-80 °C
Rat OPA1 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_133585
Species:
Rat
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4751294
Datasheet
Catalog No. ABIN4751294
Type:
cDNA
Application:
Cloning
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_133585
Species:
Rat
Synonyms:
Opa1, OPA1, opa1
Insert length:
3200 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human OPA1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_130837
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4836619
Datasheet
Catalog No. ABIN4836619
Type:
cDNA
Application:
Cloning
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_130837
Species:
Human
Synonyms:
Opa1, OPA1, opa1
Insert length:
831 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat OPA1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_133585
Species:
Rat
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4690037
Datasheet
Catalog No. ABIN4690037
Type:
cDNA
Application:
Cloning
Gene:
Optic Atrophy 1 (Autosomal Dominant) (OPA1)
NCBI Accession:
NM_133585
Species:
Rat
Synonyms:
Opa1, OPA1, opa1
Insert length:
3200 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL4
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-C-Myc-DDK
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pLenti-C-mGFP
    • pRS
    • pCas-Guide
    • pCMV6-XL5
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to OPA1

  • OPA1, mitochondrial dynamin like GTPase (Opa1)
  • OPA1, mitochondrial dynamin like GTPase (OPA1)
  • optic atrophy 1 (autosomal dominant) (opa1)
  • 1200011N24Rik
  • AI225888
  • AI847218
  • fk62d06
  • largeG
  • lilr3
  • MGM1
  • mKIAA0567
  • NPG
  • NTG
  • wu:fb77a10
  • wu:fk62d06
  • zgc:92092

Gene-IDs for different species

Protein level used designations for OPA1

  • dynamin-like 120 kDa protein, mitochondrial
  • large GTP-binding protein
  • largeG
  • optic atrophy 1 homolog
  • optic atrophy protein 1 homolog
  • RN protein
  • optic atrophy 1 (autosomal dominant)
  • optic atrophy 1-like protein
  • dynamin-like guanosine triphosphatase
  • mitochondrial dynamin-like GTPase
  • optic atrophy protein 1
Other products related to OPA1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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